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Mouse models

A phosphorous-based dendrimer targets mitochondria and normalizes the keratinocyte proliferation/differentiation balance to improve psoriasis

Emily Clement, Ranime Jebbawi, Abdelouahd Oukhrib, Hélène Labie, Maëlys Le Moal, Séverine Fruchon, Stéphanie Cassel, Anne-Marie Caminade, Cédric-Olivier Turrin, Muriel Blanzat, Michel Simon, Rémy Poupot

published 31 Mar 2026

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A novel genetic strategy to interrogate an unknown phenotypic modifier: Sdhc KO-Robertsonian mice develop frequent thyroid abnormalities with papillary thyroid carcinoma-like features

Jean-Pierre Bayley, Heggert G. Rebel, Peter Devilee

published 31 Mar 2026

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5-HT1B receptor agonists promote Schwann cell myelination

Yuka Kobayashi-Ujiie, Keiko Hiraki-Kamon, Shuji Wakatsuki, Toshiyuki Araki

published 27 Mar 2026

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STING pathway contributes to Steroid-Hyporesponsive Lung Inflammation in DSS-induced colitis mice model

Mariam Wed Eladham, Narjes Saheb Sharif-Askari, Bushra Mdkhana, Shirin Ali, Baraa Khalid Salah Al-Sheakly, Nival Ali, Balachandar Selvakumar, Fatemeh Saheb Sharif-Askari, Ibrahim Hachim, Rabih Halwani

published 27 Mar 2026

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APOE4 and doxorubicin impair inhibitory interneuron function and homeostatic regulation in the entorhinal cortex

Nancy Luo, Harshul Pandit, Shreya Kalra, Erin Tran, Jeanne Mandelblatt, Stefano Vicini, G. William Rebeck

published 26 Mar 2026

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Inhibition of transient receptor potential vanilloid 1 (TRPV1) by a novel selective antagonist for anti-nociceptive effect on inflammatory pain without hyperthermia

Jialiang Guan, Chenru Zhao, Qiqi Zhou, Chao Zhu

published 25 Mar 2026

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M₅ positive allosteric modulation alleviates parkinsonian motor deficits

Nicole E. Chambers, Dominic Hall, Morgan Kaplan, Sarah Garan, Tyler Eichner, Mark S. Moehle

published 25 Mar 2026

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Impact of blast exposure on visual pathway: Mechanism exploration and novel diagnostic perspectives

Yue Wang, Nan Yang, Xiaofan Chen, Xing Chen, Yalei Ning, Rongdi Yuan

published 25 Mar 2026

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The METTL3 inhibitor STM2457 suppresses gastric cancer progression by modulating m⁶A RNA modification

Hang Sun, Haozhi Xu, Junying Li, Xiaoman Xie, Junmei Zhang, Hongjie Dong, Huanhuan Xie, Qi Wang, Guihua Zhao, Kun Yin, Jingyu Yang, Jianwei Zhou, Ruili Wu, Chao Xu

published 24 Mar 2026

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Effects of GABAAR modulators CL218872 and MRK-016 on neural repair and synaptic plasticity in mice with Intracerebral hemorrhage

Tingting Chen, Hongxia He, Fei Huang, Junwu Liu, Hongli Zhou, Lei Xu

published 23 Mar 2026

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Internal gene segments from a mouse-adapted influenza B virus confer increased pathogenicity to mice

Arne Matthys, Laura Amelinck, Anouk Smet, Tine Ysenbaert, Thorsten U. Vogel, Xavier Saelens, João Paulo Portela Catani

published 23 Mar 2026

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GBP2 promotes podocyte pyroptosis and contributes to the pathogenesis of pediatric lupus nephritis

Yu Sun, Jiahui Wei, Yanjun Zhao, Xingbo Jiang, Chao He, Xianhui Huang, Fengying Lei, Yuanhan Qin

published 19 Mar 2026

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Evaluation of a commercial AI-assisted cell counting software for dopaminergic neurons across species

Ken Kunugitani, Masanori Sawamura, Tomoyuki Taguchi, Tetsuya Hirato, Norihito Uemura, Takashi Ayaki, Etsuro Nakanishi, Hodaka Yamakado, Tomoyuki Ishimoto, Hirotaka Onoe, Tadashi Isa, Riki Matsumoto, Ryosuke Takahashi

published 17 Mar 2026

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