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Mouse models

Immunomodulation of Antigen Presenting Cells Promotes Natural Regulatory T Cells That Prevent Autoimmune Diabetes in NOD Mice

Martin J. Richer, Danielle J. Lavallée, Iryna Shanina, Marc S. Horwitz

published 15 Feb 2012

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Identification of Stk25 as a Genetic Modifier of Tau Phosphorylation in Dab1-Mutant Mice

Tohru Matsuki, Mariam Zaka, Rita Guerreiro, Marcel P. van der Brug, Jonathan A. Cooper, Mark R. Cookson, John A. Hardy, Brian W. Howell

published 15 Feb 2012

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Nanobiopolymer for Direct Targeting and Inhibition of EGFR Expression in Triple Negative Breast Cancer

Satoshi Inoue, Rameshwar Patil, Jose Portilla-Arias, Hui Ding, Bindu Konda, Andres Espinoza, Dmitriy Mongayt, Janet L. Markman, Adam Elramsisy, H. Westley Phillips, Keith L. Black, Eggehard Holler, Julia Y. Ljubimova

published 15 Feb 2012

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Morphological and Functional Changes in the Retina after Chronic Oxygen-Induced Retinopathy

Shinsuke Nakamura, Shunsuke Imai, Hiromi Ogishima, Kazuhiro Tsuruma, Masamitsu Shimazawa, Hideaki Hara

published 14 Feb 2012

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PKC Theta Ablation Improves Healing in a Mouse Model of Muscular Dystrophy

Luca Madaro, Andrea Pelle, Carmine Nicoletti, Annunziata Crupi, Valeria Marrocco, Gianluca Bossi, Silvia Soddu, Marina Bouché

published 14 Feb 2012

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Auditory Function in the Tc1 Mouse Model of Down Syndrome Suggests a Limited Region of Human Chromosome 21 Involved in Otitis Media

Stephanie Kuhn, Neil Ingham, Selina Pearson, Susan M. Gribble, Stephen Clayton, Karen P. Steel, Walter Marcotti

published 14 Feb 2012

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Losartan Slows Pancreatic Tumor Progression and Extends Survival of SPARC-Null Mice by Abrogating Aberrant TGFβ Activation

Shanna A. Arnold, Lee B. Rivera, Juliet G. Carbon, Jason E. Toombs, Chi-Lun Chang, Amy D. Bradshaw, Rolf A. Brekken

published 14 Feb 2012

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Nilotinib and Imatinib Are Comparably Effective in Reducing Growth of Human Eosinophil Leukemia Cells in a Newly Established Xenograft Model

Daniel Wicklein, Nuno Ramos Leal, Johannes Salamon, Mohammed Thamer, Harald Herrmann, Peter Valent, Udo Schumacher, Sebastian Ullrich

published 14 Feb 2012

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Fetal Radiation Exposure Induces Testicular Cancer in Genetically Susceptible Mice

Gunapala Shetty, Paul B. Comish, Connie C. Y. Weng, Angabin Matin, Marvin L. Meistrich

published 13 Feb 2012

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Contrasting Roles for CD4 vs. CD8 T-Cells in a Murine Model of Virally Induced “T1 Black Hole” Formation

Istvan Pirko, Yi Chen, Anne K. Lohrey, Jeremiah McDole, Jeffrey D. Gamez, Kathleen S. Allen, Kevin D. Pavelko, Diana M. Lindquist, R. Scott Dunn, Slobodan I. Macura, Aaron J. Johnson

published 13 Feb 2012

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Allele-Specific Deletions in Mouse Tumors Identify Fbxw7 as Germline Modifier of Tumor Susceptibility

Jesus Perez-Losada, Di Wu, Reyno DelRosario, Allan Balmain, Jian-Hua Mao

published 13 Feb 2012

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PGC-1α Determines Light Damage Susceptibility of the Murine Retina

Anna Egger, Marijana Samardzija, Vithiyanjali Sothilingam, Naoyuki Tanimoto, Christina Lange, Silvia Salatino, Lei Fang, Marina Garcia-Garrido, Susanne Beck, Michal J. Okoniewski, Albert Neutzner, Mathias W. Seeliger, Christian Grimm, Christoph Handschin

published 13 Feb 2012

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Analysis of the Fibroblast Growth Factor System Reveals Alterations in a Mouse Model of Spinal Muscular Atrophy

Niko Hensel, Andreas Ratzka, Hella Brinkmann, Lars Klimaschewski, Claudia Grothe, Peter Claus

published 13 Feb 2012

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