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Mouse models

KCN1, a Novel Synthetic Sulfonamide Anticancer Agent: In Vitro and In Vivo Anti-Pancreatic Cancer Activities and Preclinical Pharmacology

Wei Wang, Lin Ao, [ ... ], Ruiwen Zhang

Keratinocyte Growth Factor Improves Epithelial Structure and Function in a Mouse Model of Intestinal Ischemia/Reperfusion

Yujiao Cai, Wensheng Wang, [ ... ], Hua Yang

The mTOR Inhibitor Rapamycin Has Limited Acute Anticonvulsant Effects in Mice

Adam L. Hartman, Polan Santos, Alison Dolce, J. Marie Hardwick

Fragments of HdhQ150 Mutant Huntingtin Form a Soluble Oligomer Pool That Declines with Aggregate Deposition upon Aging

David Marcellin, Dorothee Abramowski, [ ... ], Gregor P. Lotz

Norcantharidin Facilitates LPS-Mediated Immune Responses by Up-Regulation of AKT/NF-κB Signaling in Macrophages

Qufei Zhao, Yu Qian, [ ... ], Bing Du

Comprehensive Analysis of Ultrasonic Vocalizations in a Mouse Model of Fragile X Syndrome Reveals Limited, Call Type Specific Deficits

Snigdha Roy, Nick Watkins, Detlef Heck

Multi-Scale Biomechanical Remodeling in Aging and Genetic Mutant Murine Mitral Valve Leaflets: Insights into Marfan Syndrome

Russell A. Gould, Ravi Sinha, [ ... ], Jonathan Butcher

Anti-Tumor Effects of the Peptide TMTP1-GG-_D(KLAKLAK)² on Highly Metastatic Cancers

Xiangyi Ma, Ling Xi, [ ... ], Ding Ma

Msh2 Acts in Medium-Spiny Striatal Neurons as an Enhancer of CAG Instability and Mutant Huntingtin Phenotypes in Huntington’s Disease Knock-In Mice

Marina Kovalenko, Ella Dragileva, [ ... ], Vanessa C. Wheeler

Re-Expression of IGF-II Is Important for Beta Cell Regeneration in Adult Mice

Luxian Zhou, Stella Pelengaris, [ ... ], Michael Khan

Breaking Tolerance in Transgenic Mice Expressing the Human TSH Receptor A-Subunit: Thyroiditis, Epitope Spreading and Adjuvant as a ‘Double Edged Sword’

Sandra M. McLachlan, Holly A. Aliesky, [ ... ], Basil Rapoport

Potential Role of Estrogen Receptor Beta as a Tumor Suppressor of Epithelial Ovarian Cancer

Carine Bossard, Muriel Busson, [ ... ], Gwendal Lazennec

The Hsp90 Co-Chaperone Sgt1 Governs Candida albicans Morphogenesis and Drug Resistance

Rebecca S. Shapiro, Aimee K. Zaas, [ ... ], Leah E. Cowen

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