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Mouse models

Idebenone Protects against Retinal Damage and Loss of Vision in a Mouse Model of Leber’s Hereditary Optic Neuropathy

Fabrice D. Heitz, Michael Erb, Corinne Anklin, Dimitri Robay, Vincent Pernet, Nuri Gueven

published 18 Sep 2012

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Low Bone Strength Is a Manifestation of Phenylketonuria in Mice and Is Attenuated by a Glycomacropeptide Diet

Patrick Solverson, Sangita G. Murali, Suzanne J. Litscher, Robert D. Blank, Denise M. Ney

published 18 Sep 2012

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Global Renal Gene Expression Profiling Analysis in B₂-Kinin Receptor Null Mice: Impact of Diabetes

Miran A. Jaffa, Firas Kobeissy, Moustafa Al Hariri, Hussein Chalhoub, Assaad Eid, Fuad N. Ziyadeh, Ayad A. Jaffa

published 18 Sep 2012

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Tumor Selective Cytotoxic Action of a Thiomorpholin Hydroxamate Inhibitor (TMI-1) in Breast Cancer

Lynda Mezil, Carole Berruyer-Pouyet, Olivier Cabaud, Emmanuelle Josselin, Sébastien Combes, Jean-Michel Brunel, Patrice Viens, Yves Collette, Daniel Birnbaum, Marc Lopez

published 18 Sep 2012

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Metformin Prevents and Reverses Inflammation in a Non-Diabetic Mouse Model of Nonalcoholic Steatohepatitis

Yuki Kita, Toshinari Takamura, Hirofumi Misu, Tsuguhito Ota, Seiichiro Kurita, Yumie Takeshita, Masafumi Uno, Naoto Matsuzawa-Nagata, Ken-ichiro Kato, Hitoshi Ando, Akio Fujimura, Koji Hayashi, Toru Kimura, Yinhua Ni, Toshiki Otoda, Ken-ichi Miyamoto, Yoh Zen, Yasuni Nakanuma, Shuichi Kaneko

published 18 Sep 2012

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Characteristics of Multi-Organ Lymphangiectasia Resulting from Temporal Deletion of Calcitonin Receptor-Like Receptor in Adult Mice

Samantha L. Hoopes, Helen H. Willcockson, Kathleen M. Caron

published 17 Sep 2012

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EZN-2208 (PEG-SN38) Overcomes ABCG2-Mediated Topotecan Resistance in BRCA1-Deficient Mouse Mammary Tumors

Serge A. L. Zander, Wendy Sol, Lee Greenberger, Yixian Zhang, Olaf van Tellingen, Jos Jonkers, Piet Borst, Sven Rottenberg

published 17 Sep 2012

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Local Effects of Regulatory T Cells in MUC1 Transgenic Mice Potentiate Growth of MUC1 Expressing Tumor Cells In Vivo

Daisuke Sugiura, Kaori Denda-Nagai, Mitsuyo Takashima, Ryuichi Murakami, Shigenori Nagai, Kazuyoshi Takeda, Tatsuro Irimura

published 17 Sep 2012

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Reduced BMP Signaling Results in Hindlimb Fusion with Lethal Pelvic/Urogenital Organ Aplasia: A New Mouse Model of Sirenomelia

Kentaro Suzuki, Yasuha Adachi, Tomokazu Numata, Shoko Nakada, Motoko Yanagita, Naomi Nakagata, Sylvia M. Evans, Daniel Graf, Aris Economides, Ryuma Haraguchi, Anne M. Moon, Gen Yamada

published 17 Sep 2012

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A Mouse Model of Early-Onset Renal Failure Due to a Xanthine Dehydrogenase Nonsense Mutation

Sian E. Piret, Christopher T. Esapa, Caroline M. Gorvin, Rosie Head, Nellie Y. Loh, Olivier Devuyst, Gethin Thomas, Steve D. M. Brown, Matthew Brown, Peter Croucher, Roger Cox, Rajesh V. Thakker

published 14 Sep 2012

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Inhibition of the HCV Core Protein on the Immune Response to HBV Surface Antigen and on HBV Gene Expression and Replication In Vivo

Wenbo Zhu, Chunchen Wu, Wanyu Deng, Rongjun Pei, Yun Wang, Liang Cao, Bo Qin, Mengji Lu, Xinwen Chen

published 14 Sep 2012

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SIRT1 and c-Myc Promote Liver Tumor Cell Survival and Predict Poor Survival of Human Hepatocellular Carcinomas

Kyu Yun Jang, Sang Jae Noh, Nadja Lehwald, Guo-Zhong Tao, David I. Bellovin, Ho Sung Park, Woo Sung Moon, Dean W. Felsher, Karl G. Sylvester

published 14 Sep 2012

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Development of Transgenic Mice Containing an Introduced Stop Codon on the Human Methylmalonyl-CoA Mutase Locus

Nicole E. Buck, Harriet Dashnow, James J. Pitt, Leonie R. Wood, Heidi L. Peters

published 14 Sep 2012

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