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Mouse models

Humanized Mouse Model of Skin Inflammation Is Characterized by Disturbed Keratinocyte Differentiation and Influx of IL-17A Producing T Cells

Vivian L. de Oliveira, Romy R. M. C. Keijsers, Peter C. M. van de Kerkhof, Marieke M. B. Seyger, Esther Fasse, Lars Svensson, Markus Latta, Hanne Norsgaard, Tord Labuda, Pieter Hupkens, Piet E. J. van Erp, Irma Joosten, Hans J. P. M. Koenen

published 19 Oct 2012

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Inorganic Phosphate Accelerates the Migration of Vascular Smooth Muscle Cells: Evidence for the Involvement of miR-223

Ashraf Yusuf Rangrez, Eléonore M'Baya-Moutoula, Valérie Metzinger-Le Meuth, Lucie Hénaut, Mohamed Seif el Islam Djelouat, Joyce Benchitrit, Ziad A. Massy, Laurent Metzinger

published 18 Oct 2012

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Quercetin Inhibits Angiogenesis Mediated Human Prostate Tumor Growth by Targeting VEGFR- 2 Regulated AKT/mTOR/P70S6K Signaling Pathways

Poyil Pratheeshkumar, Amit Budhraja, Young-Ok Son, Xin Wang, Zhuo Zhang, Songze Ding, Lei Wang, Andrew Hitron, Jeong-Chae Lee, Mei Xu, Gang Chen, Jia Luo, Xianglin Shi

published 18 Oct 2012

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Nicotinamide Mononucleotide Adenylyltransferase 2 (Nmnat2) Regulates Axon Integrity in the Mouse Embryo

Amy N. Hicks, Diego Lorenzetti, Jonathan Gilley, Baisong Lu, Karl-Erik Andersson, Carol Miligan, Paul A. Overbeek, Ronald Oppenheim, Colin E. Bishop

published 17 Oct 2012

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Phosphorylation of 4E-BP1 in the Mammalian Brain Is Not Altered by LRRK2 Expression or Pathogenic Mutations

Alzbeta Trancikova, Adamantios Mamais, Philip J. Webber, Klodjan Stafa, Elpida Tsika, Liliane Glauser, Andrew B. West, Rina Bandopadhyay, Darren J. Moore

published 17 Oct 2012

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Pseudomonas aeruginosa Keratitis in Mice: Effects of Topical Bacteriophage KPP12 Administration

Ken Fukuda, Waka Ishida, Jumpei Uchiyama, Mohammad Rashel, Shin-ichiro Kato, Tamae Morita, Asako Muraoka, Tamaki Sumi, Shigenobu Matsuzaki, Masanori Daibata, Atsuki Fukushima

published 17 Oct 2012

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Routine Habitat Change: A Source of Unrecognized Transient Alteration of Intestinal Microbiota in Laboratory Mice

Betty W. Ma, Nicholas A. Bokulich, Patricia A. Castillo, Anchasa Kananurak, Mark A. Underwood, David A. Mills, Charles L. Bevins

published 17 Oct 2012

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Monitoring Bacterial Burden, Inflammation and Bone Damage Longitudinally Using Optical and μCT Imaging in an Orthopaedic Implant Infection in Mice

Jared A. Niska, Jeffrey A. Meganck, Jonathan R. Pribaz, Jonathan H. Shahbazian, Ed Lim, Ning Zhang, Brad W. Rice, Ali Akin, Romela Irene Ramos, Nicholas M. Bernthal, Kevin P. Francis, Lloyd S. Miller

published 17 Oct 2012

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Altered Regulation of Akt Signaling with Murine Cerebral Malaria, Effects on Long-Term Neuro-Cognitive Function, Restoration with Lithium Treatment

Minxian Dai, Brandi Freeman, Henry J. Shikani, Fernando Pereira Bruno, J. Elias Collado, Rolando Macias, Sandra E. Reznik, Peter Davies, David Conover Spray, Herbert Bernard Tanowitz, Louis Martin Weiss, Mahalia Sabrina Desruisseaux

published 17 Oct 2012

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Genome Analysis of a Highly Virulent Serotype 1 Strain of Streptococcus pneumoniae from West Africa

Tiffany M. Williams, Nicholas J. Loman, Chinelo Ebruke, Daniel M. Musher, Richard A. Adegbola, Mark J. Pallen, George M. Weinstock, Martin Antonio

published 17 Oct 2012

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High-Throughput 13-Parameter Immunophenotyping Identifies Shifts in the Circulating T-Cell Compartment Following Reperfusion in Patients with Acute Myocardial Infarction

Jedrzej Hoffmann, Karel Fiser, Jolanta Weaver, Ian Dimmick, Monika Loeher, Hanspeter Pircher, Carmen Martin-Ruiz, Murugapathy Veerasamy, Bernard Keavney, Thomas von Zglinicki, Ioakim Spyridopoulos

published 16 Oct 2012

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Soluble IL-2Rα (sCD25) Exacerbates Autoimmunity and Enhances the Development of Th17 Responses in Mice

Shane E. Russell, Anne C. Moore, Padraic G. Fallon, Patrick T. Walsh

published 15 Oct 2012

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Conditional Astroglial Rictor Overexpression Induces Malignant Glioma in Mice

Tariq Bashir, Cheri Cloninger, Nicholas Artinian, Lauren Anderson, Andrew Bernath, Brent Holmes, Angelica Benavides-Serrato, Nesrin Sabha, Robert N. Nishimura, Abhijit Guha, Joseph Gera

published 15 Oct 2012

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