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Mouse models

Ribitol dose-dependently enhances matriglycan expression and improves muscle function with prolonged life span in limb girdle muscular dystrophy 2I mouse model

Bo Wu, Morgan Drains, [ ... ], Qi Long Lu

Maternal immune activation induces methylation changes in schizophrenia genes

Thomas Johnson, Defne Saatci, Lahiru Handunnetthi

Pax6 mutant cerebral organoids partially recapitulate phenotypes of Pax6 mutant mouse strains

Nurfarhana Ferdaos, Sally Lowell, John O. Mason

Monoallelic variants resulting in substitutions of MAB21L1 Arg51 Cause Aniridia and microphthalmia

Hildegard Nikki Hall, Hemant Bengani, [ ... ], David R. FitzPatrick

Cysteinyl leukotriene receptor 1 is dispensable for osteoclast differentiation and bone resorption

Hirofumi Fujita, Aoi Ando, [ ... ], Hideyo Ohuchi

Genetic ablation of metabotropic glutamate receptor 5 in rats results in an autism-like behavioral phenotype

Adrien A. Eshraghi, Idil Memis, [ ... ], Rahul Mittal

Induced inactivation of Wnt16 in young adult mice has no impact on osteoarthritis development

Anna E. Törnqvist, Karin H. Nilsson, [ ... ], Sofia Movérare-Skrtic

Circulatory C-type natriuretic peptide reduces mucopolysaccharidosis-associated craniofacial hypoplasia in vivo

Marina Kashiwagi, Kazumasa Nakao, [ ... ], Kazuhisa Bessho

Loss of GPR40 in LDL receptor-deficient mice exacerbates high-fat diet-induced hyperlipidemia and nonalcoholic steatohepatitis

Zhongyang Lu, Yanchun Li, [ ... ], Yan Huang

All-trans retinoic acid (ATRA) regulates key genes in the RARG-TOP2B pathway and reduces anthracycline-induced cardiotoxicity

Jafar S. Hasbullah, Erika N. Scott, [ ... ], Colin J. D. Ross

Bin1 targeted immunotherapy alters the status of the enteric neurons and the microbiome during ulcerative colitis treatment

Sunil Thomas, Giancarlo Mercogliano, George C. Prendergast

Microglia have limited influence on early prion pathogenesis, clearance, or replication

Brent Race, Katie Williams, [ ... ], James A. Carroll

The lymphocyte-specific protein tyrosine kinase-specific inhibitor A-770041 attenuates lung fibrosis via the suppression of TGF-β production in regulatory T-cells

Kozo Kagawa, Seidai Sato, [ ... ], Yasuhiko Nishioka

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