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Mouse models

Single-cell RNA sequencing analysis of human Alzheimer’s disease brain samples reveals neuronal and glial specific cells differential expression

Lilach Soreq, Hannah Bird, Wael Mohamed, John Hardy

published 24 Feb 2023

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Salivary gland LAMP3 mRNA expression is a possible predictive marker in the response to hydroxychloroquine in Sjögren’s disease

Hiroyuki Nakamura, Tsutomu Tanaka, Youngmi Ji, Changyu Zheng, Sandra A. Afione, Blake M. Warner, Fabiola Reis Oliveira, Ana Carolina F. Motta, Eduardo M. Rocha, Masayuki Noguchi, Tatsuya Atsumi, John A. Chiorini

published 23 Feb 2023

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Rhodopsin-positive cell production by intravitreal injection of small molecule compounds in mouse models of retinal degeneration

Yuya Fujii, Mitsuru Arima, Yusuke Murakami, Koh-Hei Sonoda

published 23 Feb 2023

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Novel Bruton’s tyrosine kinase inhibitor TAS5315 suppresses the progression of inflammation and joint destruction in rodent collagen-induced arthritis

Daichi Akasaka, Satoru Iguchi, Ryusuke Kaneko, Yohei Yoshiga, Daisuke Kajiwara, Yoshinori Nakachi, Naruto Noma, Kenji Tanaka, Atsushi Shimizu, Fumihito Hosoi

published 23 Feb 2023

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A new strategy to prevent biofilm and clot formation in medical devices: The use of atmospheric non-thermal plasma assisted deposition of silver-based nanostructured coatings

Tommaso Gallingani, Elisa Resca, Massimo Dominici, Giuliana Gavioli, Romolo Laurita, Anna Liguori, Giorgio Mari, Luca Ortolani, Eva Pericolini, Arianna Sala, Giulia Laghi, Tiziana Petrachi, Gaëlle Francoise Arnauld, Luca Accorsi, Rita Rizzoli, Vittorio Colombo, Matteo Gherardi, Elena Veronesi

published 22 Feb 2023

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Intestinal edema induced by LPS-induced endotoxemia is associated with an inflammasome adaptor ASC

Toshihiro Yamamoto, Mie Kurata, Naoe Kaneko, Junya Masumoto

published 17 Feb 2023

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An older diabetes-induced mice model for studying skin wound healing

Carlos Poblete Jara, Guilherme Nogueira, Joseane Morari, Thaís Paulino do Prado, Renan de Medeiros Bezerra, Lício A. Velloso, William Velander, Eliana Pereira de Araújo

published 17 Feb 2023

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Imiquimod induces skin inflammation in humanized BRGSF mice with limited human immune cell activity

Pernille Kristine Fisker Christensen, Axel Kornerup Hansen, Søren Skov, Britta Cathrina Martel, Jesper Larsen, Maria Helena Høyer-Hansen, Janne Koch

published 17 Feb 2023

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Immunopathological mechanisms in the early stage of Mycobacterium avium subsp. paratuberculosis infection via different administration routes in a murine model

Jun Ho Lee, Hong-Tae Park, Soojin Shim, Suji Kim, Sang-Ho Woo, Dae-Yong Kim, Han Sang Yoo

published 16 Feb 2023

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Chondromodulin is necessary for cartilage callus distraction in mice

Kiminori Yukata, Chisa Shukunami, Yoshito Matsui, Aki Takimoto, Tomohiro Goto, Mitsuhiko Takahashi, Atsushi Mihara, Tetsuya Seto, Takashi Sakai, Yuji Hiraki, Natsuo Yasui

published 16 Feb 2023

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Visualizing increased uptake of [¹⁸F]FDG and [¹⁸F]FTHA in kidneys from obese high-fat diet fed C57BL/6J mice using PET/CT ex vivo

Rakel Nyrén, Henrik Scherman, Jan Axelsson, Chuchun L. Chang, Gunilla Olivecrona, Madelene Ericsson

published 14 Feb 2023

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Treatment of tubular damage in high-fat-diet-fed obese mice using sodium-glucose co-transporter inhibitors

Sei Saitoh, Takashi Takaki, Kazuki Nakajima, Bao Wo, Hiroshi Terashima, Satoshi Shimo, Huy Bang Nguyen, Truc Quynh Thai, Kanako Kumamoto, Kazuo Kunisawa, Shizuko Nagao, Akihiro Tojo, Nobuhiko Ohno, Kazuo Takahashi

published 13 Feb 2023

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Comparison of the efficacy of second and third generation lentiviral vector transduced CAR CD19 T cells for use in the treatment of acute lymphoblastic leukemia both in vitro and in vivo models

Piamsiri Sawaisorn, Korakot Atjanasuppat, Kitipong Uaesoontrachoon, Parin Rattananon, Worapapar Treesuppharat, Suradej Hongeng, Usanarat Anurathapan

published 13 Feb 2023

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