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Mouse models

Identification of curaxin as a potential new therapeutic for JAK2 V617F mutant patients

Stella Pearson, Rognvald Blance, Fei Yan, Ya-Ching Hsieh, Bethany Geary, Fabio M. R. Amaral, Tim C. P. Somervaille, Kristina Kirschner, Anthony D. Whetton, Andrew Pierce

published 30 May 2023

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Beta1-receptor blockade attenuates atherosclerosis progression following traumatic brain injury in apolipoprotein E deficient mice

Jintao Wang, Jessica Venugopal, Paul Silaghi, Enming J. Su, Chiao Guo, Daniel A. Lawrence, Daniel T. Eitzman

published 26 May 2023

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A new NASH model in aged mice with rapid progression of steatohepatitis and fibrosis

Xuecheng Li, Yi Lu, Xiaoshuang Liang, Xiaofei Zhou, Dirui Li, Zan Zhang, Yunchao Niu, Shuaishuai Liu, Ling Ye, Rufeng Zhang

published 25 May 2023

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Investigation of artificial intelligence integrated fluorescence endoscopy image analysis with indocyanine green for interpretation of precancerous lesions in colon cancer

Jinhyeon Kim, Hajung Kim, Yong Sik Yoon, Chan Wook Kim, Seung-Mo Hong, Sungjee Kim, Doowon Choi, Jihyun Chun, Seung Wook Hong, Sung Wook Hwang, Sang Hyoung Park, Dong-Hoon Yang, Byong Duk Ye, Jeong-Sik Byeon, Suk-Kyun Yang, Sun Young Kim, Seung-Jae Myung

published 25 May 2023

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In vitro myelination using explant culture of dorsal root ganglia: An efficient tool for analyzing peripheral nerve differentiation and disease modeling

Yurika Numata-Uematasu, Shuji Wakatsuki, Yuka Kobayashi-Ujiie, Kazuhisa Sakai, Noritaka Ichinohe, Toshiyuki Araki

published 24 May 2023

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Mice lacking Ptprd exhibit deficits in goal-directed behavior and female-specific impairments in sensorimotor gating

Emily V. Ho, Amanda Welch, Summer L. Thompson, James A. Knowles, Stephanie C. Dulawa

published 19 May 2023

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Unsaturated or saturated dietary fat-mediated steatosis impairs hepatic regeneration following partial hepatectomy in mice

S. M. Touhidul Islam, Arun P. Palanisamy, Gabriel R. Chedister, Michael G. Schmidt, David N. B. Lewin, Kenneth D. Chavin

published 11 May 2023

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Heterozygosity for ADP-ribosylation factor 6 suppresses the burden and severity of atherosclerosis

Venkateswara R. Gogulamudi, Md Torikul Islam, Jessica R. Durrant, Adelola O. Adeyemo, Daniel W. Trott, Mi Ho Hyuhn, Weiquan Zhu, Anthony J. Donato, Ashley E. Walker, Lisa A. Lesniewski

published 10 May 2023

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3D doppler ultrasound imaging of cerebral blood flow for assessment of neonatal hypoxic-ischemic brain injury in mice

Guofang Shen, Kayla Sanchez, Shirley Hu, Zhen Zhao, Lubo Zhang, Qingyi Ma

published 09 May 2023

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Machine learning for spatial stratification of progressive cardiovascular dysfunction in a murine model of type 2 diabetes mellitus

Andrya J. Durr, Anna S. Korol, Quincy A. Hathaway, Amina Kunovac, Andrew D. Taylor, Saira Rizwan, Mark V. Pinti, John M. Hollander

published 08 May 2023

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Identification of stably expressed Internal Control Genes (ICGs) for normalization of expression data in liver of C57BL/6 mice injected with beta casomorphins

Anurag Kumar, Monika Sodhi, Manishi Mukesh, Amandeep Kaur, Gaurav Bhakri, Vipul Chaudhary, Preeti Swami, Vishal Sharma, Ashok Kumar Mohanty, Ranjit S. Kataria

published 05 May 2023

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Mitotic CDK1 and 4E-BP1 I: Loss of 4E-BP1 serine 82 phosphorylation promotes proliferative polycystic disease and lymphoma in aged or sublethally irradiated mice

Rui Sun, Siying Guo, Yoko Shuda, Anish B. Chakka, Lora H. Rigatti, Guangyi Zhao, Mohammed A. E. Ali, Christopher Y. Park, Uma Chandran, Jian Yu, Christopher J. Bakkenist, Masahiro Shuda, Patrick S. Moore, Yuan Chang

published 05 May 2023

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Increased serum extracellular vesicle miR-144-3p and miR-486a-3p in a mouse model of adipose tissue regeneration promote hepatocyte proliferation by targeting Txnip

Yoshihiro Niitsu, Chikara Komiya, Akira Takeuchi, Kazunari Hara, Masato Horino, Jun Aoki, Rei Okazaki, Masanori Murakami, Kazutaka Tsujimoto, Kenji Ikeda, Tetsuya Yamada

published 04 May 2023

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