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Mouse models

Computational modeling-directed combination treatment with etanercept and mifepristone mitigates neuroinflammation in a mouse model of Gulf War Illness

Kimberly A. Kelly, Christopher M. Felton, Brenda K. Billig, Ali A. Yilmaz, James P. O’Callaghan, Travis J. A. Craddock, Gordon Broderick, Nancy Klimas, Lindsay T. Michalovicz

published 17 Mar 2026

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Prenatal cannabis smoke exposure alters placental development in a murine model of pregnancy

Tina Podinic, Maria Sunil, Andie MacAndrew, Cristina Monaco, Grace Lee, Cielle Lockington, Jim Petrik, Amica-Maria Lucas, Thane Tomy, Gregg Tomy, Joanna Kasinska, Laiba Jamshed, Alison C. Holloway, Elyanne M. Ratcliffe, Sandeep Raha

published 16 Mar 2026

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A new mouse mutant with a discrete mutation in Pcdhgc5 reveals that the Protocadherin γC5 isoform is not essential for dendrite arborization in the cerebral cortex

Camille M. Hanes, David M. Steffen, George C. Murray, Robert W. Burgess, Joshua A. Weiner, Andrew M. Garrett

published 12 Mar 2026

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Exendin-4 enhances GLP-1 signaling and reduces anxiety-like behaviors in male heroin withdrawal mice

Yang Xiang, Xiaowei Yan, Rongrong Li, Chunlu Li, Dan Yin, Cancan Luo, Yingqi Xiong, Yan Hong, Yixin Li, Baijuan Xia

published 12 Mar 2026

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An Fc-silent OspA monoclonal antibody passively protects mice from tick and intradermal Borrelia burgdorferi challenge

Daniel Palmer, Atieh Shemshadian, Katherine Berman, Ariana Nobles, Graham G. Willsey, Carol Lyn Piazza, Grace Freeman-Gallant, Michael J. Rudolph, Jeff Bourgeois, Linden Hu, David J. Vance, Nicholas J. Mantis

published 12 Mar 2026

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RETRACTED: NFIC suppressed the development of Glioma via modulating the balance of SHP2/PI3K and NF-κB/PTEN Signaling

Hongen Bao, Kai Liu, Naikang Gao, Youle Su, Huiru Bai, Changwu Dou, Fenjun Jiang, Fei Wang

published 11 Mar 2026

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Comparison of neonatal systemic and intracerebroventricular AAV9 gene therapy delivery demonstrating improved behavioral and phenotypic outcomes in a mouse model of Niemann-Pick disease, type C1

Benjamin E. Epstein, Gabrielle M. Soden, Arturo A. Incao, Avani Mylvara, Jonathan Flynn, Fatih Ozsolak, William J. Pavan

published 11 Mar 2026

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Reduced levels of mitochondrial ribosomal protein MRPL54 does not alter Apc related adenoma formation

Claudia N. Spaan, Eileen Daniels, Wouter L. Smit, Ruben J. de Boer, Joana Silva, Jacqueline L. M. Vermeulen, S. Meisner, Vanesa Muncan, Riekelt H. Houtkooper, Jarom Heijmans

published 09 Mar 2026

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Minigenes for heterologous expression of human and mouse cationic trypsinogen

Gergő Berke, Miklós Sahin-Tóth

published 09 Mar 2026

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TLR9/MyD88/NF-κB signaling mediates mental stress-induced exacerbation of psoriasis through immune dysregulation in a mouse model

Qiuhe Song, Dongyang Li, Zhihao Yuan, Chaowen Zhang, Jianqiao Wang, Fangfang Liao, Pengfei Xu, Qipeng Xiao

published 06 Mar 2026

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Unbiased quantification of persistent postural and motor deficits following spinal cord injury in mice

Sarah S. Jobbins, Vihaan Pande, Chih-Wei Zeng, Helen Poldsam, Allan-Hermann Pool, Chun-Li Zhang, Helen C. Lai

published 06 Mar 2026

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Therapeutic effect and mechanism of different doses of aspirin on preterm delivery in pregnant mice

Xinlan Qu, Xuechun Wu, Xiaomeng Pang, Yuan Fang

published 05 Mar 2026

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Characterization of a spontaneous microphthalmia-like mutant mouse with isolated ocular defects

Jianying Wang, Fei Gao, Yuqiang Zheng, Mingqi Zhang, Yuzhu Zhou, Zhuoshi Wang, Jun Li

published 02 Mar 2026

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