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Mouse models

Effects of elastase-induced emphysema on muscle and bone in mice

Daichi Matsumura, Naoyuki Kawao, Katsumi Okumoto, Takashi Ohira, Yuya Mizukami, Masao Akagi, Hiroshi Kaji

published 23 Jun 2023

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The pro-resolving lipid mediator Maresin 1 ameliorates pain responses and neuroinflammation in the spared nerve injury-induced neuropathic pain: A study in male and female mice

Luísa Teixeira-Santos, Sandra Martins, Teresa Sousa, António Albino-Teixeira, Dora Pinho

published 22 Jun 2023

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Disease parameters following ocular herpes simplex virus type 1 infection are similar in male and female BALB/C mice

Aaron W. Kolb, Sarah A. Ferguson, Inna V. Larsen, Curtis R. Brandt

published 15 Jun 2023

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Endogenous interleukin-22 prevents cardiac rupture after myocardial infarction in mice

Mai Yamamoto, Hideo Yasukawa, Jinya Takahashi, Shoichiro Nohara, Tomoko Sasaki, Kodai Shibao, Daiki Akagaki, Kota Okabe, Toshiyuki Yanai, Tatsuhiro Shibata, Yoshihiro Fukumoto

published 15 Jun 2023

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Examination of two different proteasome inhibitors in reactivating mutant human cystathionine β-synthase in mice

Sapna Gupta, Hyung-Ok Lee, Liqun Wang, Warren D. Kruger

published 15 Jun 2023

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Development and anticancer properties of Up284, a spirocyclic candidate ADRM1/RPN13 inhibitor

Ravi K. Anchoori, Vidyasagar Anchoori, Brandon Lam, Ssu-Hsueh Tseng, Samarjit Das, Fernanda Carrizo Velasquez, Balasubramanyam Karanam, Deepika Poddatoori, Ramesh Patnam, Michelle A. Rudek, Yung-Nien Chang, Richard B. S. Roden

published 14 Jun 2023

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Effects of fenbendazole on fecal microbiome in BPH/5 mice, a model of hypertension and obesity, a brief report

Kalie F. Beckers, Christopher J. Schulz, Chin-Chi Liu, Elise D. Barras, Gary W. Childers, Rhett W. Stout, Jenny L. Sones

published 09 Jun 2023

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CCX559 is a potent, orally-administered small molecule PD-L1 inhibitor that induces anti-tumor immunity

Kathleen M. C. Sullivan, Marta Vilalta, Linda S. Ertl, Yu Wang, Carolyn Dunlap, Karen Ebsworth, Bin N. Zhao, Shijie Li, Yibin Zeng, Zhenhua Miao, Pingchen Fan, Venkat Mali, Christopher Lange, Darren McMurtrie, Ju Yang, Rebecca Lui, Ryan Scamp, Vicky Chhina, Alice Kumamoto, Simon Yau, Ton Dang, Ashton Easterday, Shirley Liu, Shichang Miao, Israel Charo, Thomas J. Schall, Penglie Zhang

published 07 Jun 2023

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MIC26 and MIC27 are bona fide subunits of the MICOS complex in mitochondria and do not exist as glycosylated apolipoproteins

Melissa Lubeck, Nick H. Derkum, Ritam Naha, Rebecca Strohm, Marc D. Driessen, Bengt-Frederik Belgardt, Michael Roden, Kai Stühler, Ruchika Anand, Andreas S. Reichert, Arun Kumar Kondadi

published 06 Jun 2023

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Effects of T cell leptin signaling on systemic glucose tolerance and T cell responses in obesity

Kaitlin Kiernan, Amanda G. Nichols, Yazan Alwarawrah, Nancie J. MacIver

published 05 Jun 2023

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Pterostilbene mediates glial and immune responses to alleviate chronic intermittent hypoxia-induced oxidative stress in nerve cells

Peijun Liu, Pan Zhou, Xinyue Zhang, Dong Zhao, Hao Chen, Ke Hu

published 02 Jun 2023

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Clostridium butyricum improves cognitive dysfunction in ICV-STZ-induced Alzheimer’s disease mice via suppressing TLR4 signaling pathway through the gut-brain axis

Yunfang Su, Dahui Wang, Ningning Liu, Jiajia Yang, Ruiqin Sun, Zhenqiang Zhang

published 02 Jun 2023

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Early chronic suppression of microglial p38α in a model of Alzheimer’s disease does not significantly alter amyloid-associated neuropathology

David J. Braun, Hilaree N. Frazier, Verda A. Davis, Meggie J. Coleman, Colin B. Rogers, Linda J. Van Eldik

published 31 May 2023

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