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Mouse models

Co-crystallisation and humanisation of an anti-HER2 single-domain antibody as a theranostic tool

Kovilen Sawmynaden, Nicholas Wong, [ ... ], Gareth Hall

A novel co-culture model for investigation of the effects of LPS-induced macrophage-derived cytokines on brain endothelial cells

Junling Yang, Yinchuan Li, [ ... ], Ken-ichiro Fukuchi

Delayed treatment with ceftriaxone reverses the enhanced sensitivity of TBI mice to chemically-induced seizures

Simone A. A. Romariz, Bevan S. Main, [ ... ], Mark P. Burns

Deficient AMPK activity contributes to hyperexcitability in peripheral nociceptive sensory neurons and thermal hyperalgesia in lupus mice

Viacheslav Viatchenko-Karpinski, Lingwei Kong, Han-Rong Weng

Seven naturally variant loci serve as genetic modifiers of Lamc2^jeb induced non-Herlitz junctional Epidermolysis Bullosa in mice

Thomas J. Sproule, Vivek M. Philip, [ ... ], John P. Sundberg

Variability of clinical chemical and hematological parameters, immunological parameters, and behavioral tests in data sets of the Mouse Phenome Database

Bernhard Aigner, Christian Heumann

MicroRNA-29b-3p promotes intestinal permeability in IBS-D via targeting TRAF3 to regulate the NF-κB-MLCK signaling pathway

Yongfu Wang, Wei Ke, [ ... ], Hongmei Tang

Phase 1b study on the repurposing of meclizine hydrochloride for children with achondroplasia

Masaki Matsushita, Hiroshi Kitoh, [ ... ], Shiro Imagama

Effects of heterozygous deletion of autism-related gene Cullin-3 in mice

Qiang-qiang Xia, Angela K. Walker, [ ... ], Craig M. Powell

Increased tissue modulus and hardness in the TallyHO mouse model of early onset type 2 diabetes mellitus

Daksh Arora, Erik A. Taylor, Karen B. King, Eve Donnelly

Gene knock-outs in human CD34+ hematopoietic stem and progenitor cells and in the human immune system of mice

Daniel A. Kuppers, Jonathan Linton, [ ... ], Patrick J. Paddison

Effects of elastase-induced emphysema on muscle and bone in mice

Daichi Matsumura, Naoyuki Kawao, [ ... ], Hiroshi Kaji

The pro-resolving lipid mediator Maresin 1 ameliorates pain responses and neuroinflammation in the spared nerve injury-induced neuropathic pain: A study in male and female mice

Luísa Teixeira-Santos, Sandra Martins, [ ... ], Dora Pinho

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