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Mouse models

Application of In vitro transcytosis models to brain targeted biologics

Kangwen Deng, Yifeng Lu, Sjoerd J. Finnema, Kostika Vangjeli, Junwei Huang, Lili Huang, Andrew Goodearl

published 23 Aug 2023

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Transcutaneous carbon dioxide application suppresses the expression of cancer-associated fibroblasts markers in oral squamous cell carcinoma xenograft mouse model

Yoshiaki Tadokoro, Daisuke Takeda, Aki Murakami, Nanae Yatagai, Izumi Saito, Satomi Arimoto, Yasumasa Kakei, Masaya Akashi, Takumi Hasegawa

published 18 Aug 2023

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Ferulic Acid reduces amyloid beta mediated neuroinflammation through modulation of Nurr1 expression in microglial cells

Ali Moghimi-Khorasgani, Farshad Homayouni Moghadam, Mohammad Hossein Nasr-Esfahani

published 17 Aug 2023

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Low-frequency whole-body vibration can enhance cartilage degradation with slight changes in subchondral bone in mice with knee osteoarthritis and does not have any morphologic effect on normal joints

Haiming Wang, Chi Zhang, Siyi Zhu, Chengfei Gao, Qiang Gao, Ridong Huang, Sijia Liu, Xiangyang Wei, Huakai Zhang, Quan Wei, Chengqi He

published 17 Aug 2023

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Reduced levels of A20 protein prompted RIPK1-dependent apoptosis and blood–brain barrier breakdown during cerebral ischemia reperfusion injury

Chaonan Yang, Yongjiao Wang, Xiaohui Wu, Min Gong, Ying Li

published 14 Aug 2023

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Small molecule inhibitor of tau self-association in a mouse model of tauopathy: A preventive study in P301L tau JNPL3 mice

Eliot J. Davidowitz, Patricia Lopez, Heidy Jimenez, Leslie Adrien, Peter Davies, James G. Moe

published 09 Aug 2023

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N-dihydrogalactochitosan reduces mortality in a lethal mouse model of SARS-CoV-2

Christopher M. Weiss, Hongwei Liu, Erin E. Ball, Ashley R. Hoover, Talia S. Wong, Chun Fung Wong, Samuel Lam, Tomas Hode, M. Kevin Keel, Richard M. Levenson, Wei R. Chen, Lark L. Coffey

published 08 Aug 2023

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Intestinal permeability and peripheral immune cell composition are altered by pregnancy and adiposity at mid- and late-gestation in the mouse

Tatiane A. Ribeiro, Jessica A. Breznik, Katherine M. Kennedy, Erica Yeo, Brianna K. E. Kennelly, Patrycja A. Jazwiec, Violet S. Patterson, Christian J. Bellissimo, Fernando F. Anhê, Jonathan D. Schertzer, Dawn M. E. Bowdish, Deborah M. Sloboda

published 07 Aug 2023

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In vivo Polycystin-1 interactome using a novel Pkd1 knock-in mouse model

Cheng-Chao Lin, Luis F. Menezes, Jiahe Qiu, Elisabeth Pearson, Fang Zhou, Yu Ishimoto, D. Eric Anderson, Gregory G. Germino

published 04 Aug 2023

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Nonalcoholic steatohepatitis-associated hepatocarcinogenesis in mice fed a modified choline-deficient, methionine-lowered, L-amino acid-defined diet and the role of signal changes

Noriko Suzuki-Kemuriyama, Akari Abe, Sae Nakane, Megumi Yuki, Katsuhiro Miyajima, Dai Nakae

published 03 Aug 2023

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Oocyte-specific Wee1-like protein kinase 2 is dispensable for fertility in mice

Kaori Nozawa, Zian Liao, Yuhkoh Satouh, Ting Geng, Masahito Ikawa, Diana Monsivais, Martin M. Matzuk

published 01 Aug 2023

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Indoor aeroallergens from American cockroaches and mites initiate atopic march via cutaneous contact in a murine model

Mey-Fann Lee, Yu-Wen Chu, Chi-Sheng Wu, Ming-Hao Lee, Yi-Hsing Chen, Nancy M. Wang

published 27 Jul 2023

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Wild mouse gut microbiota limits initial tuberculosis infection in BALB/c mice

Min Xie, Chen-Yu Tsai, Zachary L. McAdams, Myo Oo, Mark Hansen, Maureen Dougher, Alexander Sansano, Anderson Watson, Katherine LoMauro, Rosleine Antilus-Sainte, Aaron Ericsson, Véronique Dartois, Martin Gengenbacher

published 26 Jul 2023

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