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Mouse models

Antibody-Mediated Inhibition of TNFR1 Attenuates Disease in a Mouse Model of Multiple Sclerosis

Sarah K. Williams, Olaf Maier, Roman Fischer, Richard Fairless, Sonja Hochmeister, Aleksandar Stojic, Lara Pick, Doreen Haar, Sylvia Musiol, Maria K. Storch, Klaus Pfizenmaier, Ricarda Diem

published 28 Feb 2014

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Abrogation of TNFα Production during Cancer Immunotherapy Is Crucial for Suppressing Side Effects Due to the Systemic Expression of IL-12

Bibiana Barrios, Natalia S. Baez, Della Reynolds, Pablo Iribarren, Hugo Cejas, Howard A. Young, Maria Cecilia Rodriguez-Galan

published 28 Feb 2014

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Neuroprotective Copper Bis(thiosemicarbazonato) Complexes Promote Neurite Elongation

Laura Bica, Jeffrey R. Liddell, Paul S. Donnelly, Clare Duncan, Aphrodite Caragounis, Irene Volitakis, Brett M. Paterson, Roberto Cappai, Alexandra Grubman, James Camakaris, Peter J. Crouch, Anthony R. White

published 28 Feb 2014

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Apolipoprotein E Plays a Key Role against Cryptosporidial Infection in Transgenic Undernourished Mice

Orleâncio G. R. Azevedo, David T. Bolick, James K. Roche, Relana F. Pinkerton, Aldo A. M. Lima, Michael P. Vitek, Cirle A. Warren, Reinaldo B. Oriá, Richard L. Guerrant

published 28 Feb 2014

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Interferon-Gamma (IFN-γ)-Mediated Retinal Ganglion Cell Death in Human Tyrosinase T Cell Receptor Transgenic Mouse

Shahid Husain, Yasir Abdul, Christine Webster, Shilpak Chatterjee, Pravin Kesarwani, Shikhar Mehrotra

published 28 Feb 2014

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Abrogation of Rbpj Attenuates Experimental Autoimmune Uveoretinitis by Inhibiting IL-22-Producing CD4⁺ T Cells

Zaied Ahmed Bhuyan, Michihito Asanoma, Akiko Iwata, Chieko Ishifune, Yoichi Maekawa, Mitsuo Shimada, Koji Yasutomo

published 28 Feb 2014

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Deletion of Prepl Causes Growth Impairment and Hypotonia in Mice

Anna Mari Lone, Mathias Leidl, Amanda K. McFedries, James W. Horner, John Creemers, Alan Saghatelian

published 28 Feb 2014

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Stenotrophomonas maltophilia Virulence and Specific Variations in Trace Elements during Acute Lung Infection: Implications in Cystic Fibrosis

Arianna Pompilio, Domenico Ciavardelli, Valentina Crocetta, Ada Consalvo, Roberta Zappacosta, Carmine Di Ilio, Giovanni Di Bonaventura

published 28 Feb 2014

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Darbepoetin Alpha Reduces Oxidative Stress and Chronic Inflammation in Atherosclerotic Lesions of Apo E Deficient Mice in Experimental Renal Failure

Nicole Arend, Karl F. Hilgers, Valentina Campean, Britta Karpe, Nada Cordasic, Bernd Klanke, Kerstin Amann

published 28 Feb 2014

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Silencing of miR-34a Attenuates Cardiac Dysfunction in a Setting of Moderate, but Not Severe, Hypertrophic Cardiomyopathy

Bianca C. Bernardo, Xiao-Ming Gao, Yow Keat Tham, Helen Kiriazis, Catherine E. Winbanks, Jenny Y. Y. Ooi, Esther J. H. Boey, Susanna Obad, Sakari Kauppinen, Paul Gregorevic, Xiao-Jun Du, Ruby C. Y. Lin, Julie R. McMullen

published 27 Feb 2014

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Mebendazole Reduces Vascular Smooth Muscle Cell Proliferation and Neointimal Formation Following Vascular Injury in Mice

Jintao Wang, Hui Wang, Chiao Guo, Wei Luo, Alyssa Lawler, Aswin Reddy, Julia Wang, Eddy B. Sun, Daniel T. Eitzman

published 27 Feb 2014

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Meglumine Exerts Protective Effects against Features of Metabolic Syndrome and Type II Diabetes

Arturo Bravo-Nuevo, Alice Marcy, Minzhou Huang, Frank Kappler, Jennifer Mulgrew, Lisa Laury-Kleintop, Melvin Reichman, Annette Tobia, George C. Prendergast

published 27 Feb 2014

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Therapeutic Administration of the Chemokine CXCL1/KC Abrogates Autoimmune Inflammatory Heart Disease

Kurt Bachmaier, Sophie Toya, Asrar B. Malik

published 27 Feb 2014

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