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Mouse models

Hydroxyurea does not reverse functional alterations of the nitric oxide-cGMP pathway associated with priapism phenotype in corpus cavernosum from sickle cell mouse

Dalila Andrade Pereira, Danillo Andrade Pereira, Pamela da Silva Pereira, Tammyris Helena Rebecchi Silveira, Fabiano Beraldi Calmasini, Leonardo Oliveira Reis, Fernando Ferreira Costa, Fábio Henrique Silva

published 09 Oct 2023

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Establishment of anti-asialo-GM1 rabbit monoclonal antibodies capable of reducing natural killer cell activity in mice

Tatsuji Kimura, Satoshi Ohta, Hiroshi Murayama

published 09 Oct 2023

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Signature of cardiac alterations in early and late chronic infections with Trypanosoma cruzi in mice

Bárbara Carolina Arias-Argáez, Victor Manuel Dzul-Huchim, Ana Paulina Haro-Álvarez, Miguel Enrique Rosado-Vallado, Liliana Villanueva-Lizama, Julio Vladimir Cruz-Chan, Eric Dumonteil

published 05 Oct 2023

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Functional analysis of Collagen 17a1: A genetic modifier of junctional epidermolysis bullosa in mice

Thomas J. Sproule, Robert Y. Wilpan, Benjamin E. Low, Kathleen A. Silva, Deepak Reyon, J. Keith Joung, Michael V. Wiles, Derry C. Roopenian, John P. Sundberg

published 05 Oct 2023

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Advanced photon counting CT imaging pipeline for cardiac phenotyping of apolipoprotein E mouse models

Alex J. Allphin, Ali Mahzarnia, Darin P. Clark, Yi Qi, Zay Y. Han, Prajwal Bhandari, Ketan B. Ghaghada, Alexandra Badea, Cristian T. Badea

published 05 Oct 2023

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Long term survival and abnormal liver fat accumulation in mice with specific thymidine kinase 2 deficiency in liver tissue

Qian Zhao, Xiaoshan Zhou, Jingyi Yan, Raoul Kuiper, Sophie Curbo, Anna Karlsson

published 05 Oct 2023

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Negative regulation of angiogenesis and the MAPK pathway may be a shared biological pathway between IS and epilepsy

Longhui Fu, Beibei Yu, Boqiang Lv, Yunze Tian, Yongfeng Zhang, Huangtao Chen, Shijie Yang, Yutian Hu, Pengyu Ren, Jianzhong Li, Shouping Gong

published 04 Oct 2023

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Effects of Heparan sulfate acetyl-CoA: Alpha-glucosaminide N-acetyltransferase (HGSNAT) inactivation on the structure and function of epithelial and immune cells of the testis and epididymis and sperm parameters in adult mice

Lorena Carvelli, Louis Hermo, Cristian O’Flaherty, Richard Oko, Alexey V. Pshezhetsky, Carlos R. Morales

published 27 Sep 2023

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Modulation of cardiac cAMP signaling by AMPK and its adjustments in pressure overload-induced myocardial dysfunction in rat and mouse

Anne Garnier, Jérôme Leroy, Claudine Deloménie, Philippe Mateo, Benoit Viollet, Vladimir Veksler, Mathias Mericskay, Renée Ventura-Clapier, Jérôme Piquereau

published 21 Sep 2023

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Protective effect of paeoniflorin in diabetic nephropathy: A preclinical systematic review revealing the mechanism of action

Xue-Er Zhang, Yao-bin Pang, Qu Bo, Shuang-Yuan Hu, Ju-Yi Xiang, Zheng-Ru Yang, Xiao-Mei Zhang, An-Jing Chen, Jin-Hao Zeng, Xiao Ma, Jing Guo

published 21 Sep 2023

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Enhancement of in vivo targeting properties of ErbB2 aptamer by chemical modification

Jun Young Park, Ye Lim Cho, Ju Ri Chae, Jung Hwan Lee, Won Jun Kang

published 20 Sep 2023

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Administration of alendronate exacerbates ammonium chloride-induced acidosis in mice

Mikayla Moody, Tannin A. Schmidt, Ruchir Trivedi, Alix Deymier

published 15 Sep 2023

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Nicotinamide restores tissue NAD⁺ and improves survival in rodent models of cardiac arrest

Xiangdong Zhu, Jing Li, Huashan Wang, Filip M. Gasior, Chunpei Lee, Shaoxia Lin, Cody N. Justice, J. Michael O’Donnell, Terry L. Vanden Hoek

published 15 Sep 2023

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