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Mouse models

Rat and mouse cardiomyocytes show subtle differences in creatine kinase expression and compartmentalization

Jelena Branovets, Kärol Soodla, Marko Vendelin, Rikke Birkedal

published 27 Nov 2023

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Type of anesthesia for cancer resection surgery: No differential impact on cancer recurrence in mouse models of breast cancer

Julia Dubowitz, Alexandra I. Ziegler, Richard Beare, Fabian Jost-Brinkmann, Adam K. Walker, Ryan D. Gillis, Aeson Chang, Ni-Chun Chung, Olga A. Martin, Frédéric Hollande, Bernhard Riedel, Erica K. Sloan

published 27 Nov 2023

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Route of administration significantly affects particle deposition and cellular recruitment

Keziyah Yisrael, Ryan W. Drover, Malia L. Shapiro, Martha Anguiano, Nala Kachour, Qi Li, Emily Tran, David R. Cocker III, David D. Lo

published 27 Nov 2023

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Two mouse models of Alzheimer’s disease accumulate amyloid at different rates and have distinct Aβ oligomer profiles unaltered by ablation of cellular prion protein

Silvia A. Purro, Michael Farmer, Elizabeth Noble, Claire J. Sarell, Megan Powell, Daniel Yip, Lauren Giggins, Leila Zakka, David X. Thomas, Mark Farrow, Andrew J. Nicoll, Dominic Walsh, John Collinge

published 17 Nov 2023

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Determination of progressive stages of type 2 diabetes in a 45% high-fat diet-fed C57BL/6J mouse model is achieved by utilizing both fasting blood glucose levels and a 2-hour oral glucose tolerance test

Thuy Nguyen-Phuong, Sol Seo, Beum-Keun Cho, Jung-Ho Lee, Jiyun Jang, Chung-Gyu Park

published 14 Nov 2023

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An intravenous pancreatic cancer therapeutic: Characterization of CRISPR/Cas9n-modified Clostridium novyi-Non Toxic

Kaitlin M. Dailey, James M. Small, Jessica E. Pullan, Seth Winfree, Krysten E. Vance, Megan Orr, Sanku Mallik, Kenneth W. Bayles, Michael A. Hollingsworth, Amanda E. Brooks

published 14 Nov 2023

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HSP70 via HIF-1 α SUMOylation inhibits ferroptosis inducing lung cancer recurrence after insufficient radiofrequency ablation

Bin Peng, Xiean Ling, Tonghai Huang, Jun Wan

published 10 Nov 2023

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The placental vasculature is affected by changes in gene expression and glycogen-rich cells in a diet-induced obesity mouse model

Hui Zhao, Ronald J. Wong, David K. Stevenson

published 10 Nov 2023

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Functionally similar genes exhibit comparable/similar time-course expression kinetics in the UV-induced photoaged mouse model

Seon-Pil Jin, Joong Heon Suh, Chang-Eop Kim, Inn Gyung Oh, Eun Young Seo, Min-Kyoung Kim, Kyeong-No Yoon, Jin Ho Chung

published 09 Nov 2023

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TGF-β inhibitor treatment of H₂O₂-induced cystitis models provides biochemical mechanism for elucidating interstitial cystitis/painful bladder syndrome patients

Hideto Taga, Tsunao Kishida, Yuta Inoue, Kenta Yamamoto, Shin-ichiro Kotani, Tsujimoto Masashi, Osamu Ukimura, Osam Mazda

published 06 Nov 2023

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Development of a sensitive real-time quaking-induced conversion (RT-QuIC) assay for application in prion-infected blood

Charlotte M. Thomas, M. Khalid F. Salamat, Christopher de Wolf, Sandra McCutcheon, A. Richard Alejo Blanco, Jean C. Manson, Nora Hunter, E. Fiona Houston

published 02 Nov 2023

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Exercise performance is not improved in mice with skeletal muscle deletion of natriuretic peptide clearance receptor

Brigitte Jia, Alexander Hasse, Fubiao Shi, Sheila Collins

published 02 Nov 2023

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Intranasal challenge with B. pertussis leads to more severe disease manifestations in mice than aerosol challenge

Kelly L. Weaver, Graham J. Bitzer, M. Allison Wolf, Gage M. Pyles, Megan A. DeJong, Spencer R. Dublin, Annalisa B. Huckaby, Maria de la Paz Gutierrez, Jesse M. Hall, Ting Y. Wong, Matthew Warden, Jonathan E. Petty, William T. Witt, Casey Cunningham, Emel Sen-Kilic, F. Heath Damron, Mariette Barbier

published 02 Nov 2023

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