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Mouse models

Generation and characterization of monoclonal antibodies against pathologically phosphorylated TDP-43

Paula Castellanos Otero, Tiffany W. Todd, Wei Shao, Caroline J. Jones, Kexin Huang, Lillian M. Daughrity, Mei Yue, Udit Sheth, Tania F. Gendron, Mercedes Prudencio, Björn Oskarsson, Dennis W. Dickson, Leonard Petrucelli, Yong-Jie Zhang

published 18 Apr 2024

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SOX4 exerts contrasting regulatory effects on labor-associated gene promoters in myometrial cells

Nawrah Khader, Virlana M. Shchuka, Anna Dorogin, Oksana Shynlova, Jennifer A. Mitchell

published 18 Apr 2024

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Protective role of protease-activated receptor-2 in anaphylaxis model mice

Maho Nakazawa, Ryota Tochinai, Wataru Fujii, Mao Komori, Tomohiro Yonezawa, Yasuyuki Momoi, Shingo Maeda

published 18 Apr 2024

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Transcutaneous carbon dioxide suppresses skeletal muscle atrophy in a mouse model of oral squamous cell carcinoma

Aki Sasaki, Daisuke Takeda, Hotaka Kawai, Yoshiaki Tadokoro, Aki Murakami, Nanae Yatagai, Satomi Arimoto, Hitoshi Nagatsuka, Masaya Akashi, Takumi Hasegawa

published 17 Apr 2024

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Neuroprotective potential of Mentha piperita extract prevents motor dysfunctions in mouse model of Parkinson’s disease through anti-oxidant capacities

Rabia Anjum, Chand Raza, Mehwish Faheem, Arif Ullah, Maham Chaudhry

published 16 Apr 2024

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Phenotypes of streptozotocin-induced gestational diabetes mellitus in mice

Narumi Takahashi, Osamu Ichii, Masaya Hiraishi, Takashi Namba, Yuki Otani, Teppei Nakamura, Yasuhiro Kon

published 16 Apr 2024

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Rauwolfia polysaccharide can inhibit the progress of ulcerative colitis through NOS2-mediated JAK2/STAT3 pathway

Haidong Wu, Fan Jiang, Wei Yuan, Ye Zhao, Ning Liu, Xinpu Miao

published 16 Apr 2024

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Peak transgene expression after intramuscular immunization of mice with adenovirus 26-based vector vaccines correlates with transgene-specific adaptive immune responses

Sonia Marquez-Martinez, Nadine Salisch, Jan Serroyen, Roland Zahn, Selina Khan

published 16 Apr 2024

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Mathematical modeling of transdermal delivery of topical drug formulations in a dynamic microfluidic diffusion chamber in health and disease

Gábor Szederkényi, Dorottya Kocsis, Mihály A. Vághy, Domonkos Czárán, Péter Sasvári, Miléna Lengyel, Márton Bese Naszlady, Fabiola Kreis, István Antal, Roland Csépányi-Kömi, Franciska Erdő

published 11 Apr 2024

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Low-dose biliatresone treatment of pregnant mice causes subclinical biliary disease in their offspring: Evidence for a spectrum of neonatal injury

Kapish Gupta, Jimmy P. Xu, Tamir Diamond, Iris E. M. de Jong, Andrew Glass, Jessica Llewellyn, Neil D. Theise, Orith Waisbourd-Zinman, Jeffrey D. Winkler, Edward M. Behrens, Clementina Mesaros, Rebecca G. Wells

published 05 Apr 2024

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Preclinical evaluation of Tc-99m p5+14 peptide for SPECT detection of cardiac amyloidosis

Stephen J. Kennel, Joseph W. Jackson, Alan Stuckey, Tina Richey, James S. Foster, Jonathan S. Wall

published 05 Apr 2024

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Disruption of the mast cell carboxypeptidase A3 gene does not attenuate airway inflammation and hyperresponsiveness in two mouse models of asthma

Ida Waern, Srinivas Akula, Venkata Sita Rama Raju Allam, Sowsan Taha, Thorsten B. Feyerabend, Magnus Åbrink, Sara Wernersson

published 05 Apr 2024

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Cyclophilin D knockout significantly prevents HCC development in a streptozotocin-induced mouse model of diabetes-linked NASH

Winston T. Stauffer, Michael Bobardt, Daren R. Ure, Robert T. Foster, Philippe Gallay

published 04 Apr 2024

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