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Mouse models

The uterine secretome initiates growth of gynecologic tissues in ectopic locations

Jan Sunde, Morgan Wasickanin, Tiffany A. Katz, Laurel Gillette, Sanam Bidadi, Derek O’Neil, Ramya Masand, Richard O. Burney, Kathleen A. Pennington

published 10 May 2024

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NF-κB1 deficiency promotes macrophage-derived adrenal tumors but decreases neurofibromas in HTLV-I LTR-Tax transgenic mice

Xinxin Song, Zhaoxia Qu

published 09 May 2024

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Creation and characterization of novel rat model for recessive dystrophic epidermolysis bullosa: Frameshift mutation of the Col7a1 gene leads to severe blistered phenotype

William Stone, Chloe Strege, William Miller, Aron M. Geurts, Michael Grzybowski, Megan Riddle, Christopher Lees, Cindy Eide, Douglas R. Keene, Sara F. Tufa, Davis Seelig, John McGrath, Jakub Tolar

published 09 May 2024

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Exportin 4 DNA promoter methylation in liver fibrosis

Ziyan Pan, Ali Bayoumi, Mayada Metwally, Jacob George, Mohammed Eslam

published 09 May 2024

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Mexenone protects mice from LPS-induced sepsis by EC barrier stabilization

Yoon Ji Choi, Jimin An, Ji Hye Kim, Sa Bin Lee, Bo Seok Lee, Chae Young Eom, Hyohi Lee, Nayeong Kwon, Il Shin Kim, Kyoung-Su Park, Sooah Park, Jung-Woog Shin, Sanguk Yun

published 09 May 2024

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Evaluating possible maternal effect lethality and genetic background effects in Naa10 knockout mice

Gholson J. Lyon, Joseph Longo, Andrew Garcia, Fatima Inusa, Elaine Marchi, Daniel Shi, Max Dörfel, Thomas Arnesen, Rafael Aldabe, Scott Lyons, Melissa A. Nashat, David Bolton

published 07 May 2024

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Control of acute myeloid leukemia and generation of immune memory in vivo using AMV564, a bivalent bispecific CD33 x CD3 T cell engager

Linda G. Eissenberg, Julie K. Ritchey, Michael P. Rettig, Dilan A. Patel, Kiran Vij, Feng Gao, Victoria Smith, Tae H. Han, John F. DiPersio

published 02 May 2024

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Zhilong Huoxue Tongyu capsule improves myocardial ischemia/reperfusion injury via the PI3K/AKT/Nrf2 axis

Xiaoping Zhao, Fang Yang, Hao Wu, Zhongcai Fan, Gang Wei, Yuan Zou, Jinyi Xue, Mengnan Liu, Gong Chen

published 30 Apr 2024

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pH-responsive targeted nanoparticles release ERK-inhibitor in the hypoxic zone and sensitize free gemcitabine in mutant K-Ras-addicted pancreatic cancer cells and mouse model

Debasmita Dutta, Priyanka Ray, Archana De, Arnab Ghosh, Raj Shankar Hazra, Pratyusha Ghosh, Snigdha Banerjee, Francisco J. Diaz, Sunil P. Upadhyay, Mohiuddin Quadir, Sushanta K. Banerjee

published 30 Apr 2024

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Inhibition of SRC-3 as a potential therapeutic strategy for aggressive mantle cell lymphoma

Imani Bijou, Yang Liu, Dong Lu, Jianwei Chen, Shelby Sloan, Lapo Alinari, David M. Lonard, Bert W. O’Malley, Michael Wang, Jin Wang

published 29 Apr 2024

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Effect of SARS-CoV-2 S protein on the proteolytic cleavage of the epithelial Na⁺ channel ENaC

Germán Ricardo Magaña-Ávila, Erika Moreno, Consuelo Plata, Héctor Carbajal-Contreras, Adrian Rafael Murillo-de-Ozores, Kevin García-Ávila, Norma Vázquez, Maria Syed, Jan Wysocki, Daniel Batlle, Gerardo Gamba, María Castañeda-Bueno

published 25 Apr 2024

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Increased hepatoprotective effects of the novel farnesoid X receptor agonist INT-787 versus obeticholic acid in a mouse model of nonalcoholic steatohepatitis

Luciano Adorini, Kristoffer Rigbolt, Michael Feigh, Jonathan Roth, Mary Erickson

published 25 Apr 2024

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DFMG decreases angiogenesis to uphold plaque stability by inhibiting the TLR4/VEGF pathway in mice

Pingjuan Bai, Xueping Xiang, Jiawen Kang, Xiaoqing Xiang, Jingwen Jiang, Xiaohua Fu, Yong Zhang, Lesai Li

published 18 Apr 2024

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