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Mouse models

Neuregulin 1 Expression and Electrophysiological Abnormalities in the Neuregulin 1 Transmembrane Domain Heterozygous Mutant Mouse

Leonora E. Long, Paul Anderson, Elisabeth Frank, Alex Shaw, Shijie Liu, Xu-Feng Huang, Didier Pinault, Tim Karl, Terence J. O’Brien, Cynthia Shannon Weickert, Nigel C. Jones

published 19 May 2015

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Repositioning of Memantine as a Potential Novel Therapeutic Agent against Meningitic E. coli–Induced Pathogenicities through Disease-Associated Alpha7 Cholinergic Pathway and RNA Sequencing-Based Transcriptome Analysis of Host Inflammatory Responses

Jing-Yi Yu, Bao Zhang, Liang Peng, Chun-Hua Wu, Hong Cao, John F. Zhong, Jill Hoffman, Sheng-He Huang

published 19 May 2015

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Vascular and Hepatic Impact of Short-Term Intermittent Hypoxia in a Mouse Model of Metabolic Syndrome

Wojciech Trzepizur, Abderahim Gaceb, Claire Arnaud, Christophe Ribuot, Patrick Levy, M. Carmen Martinez, Frédéric Gagnadoux, Ramaroson Andriantsitohaina

published 18 May 2015

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Premature Expression of Foxp3 in Double-Negative Thymocytes

Melanie M. Barra, David M. Richards, Ann-Cathrin Hofer, Michael Delacher, Markus Feuerer

published 15 May 2015

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Corosolic Acid Inhibits Hepatocellular Carcinoma Cell Migration by Targeting the VEGFR2/Src/FAK Pathway

Chung-Yu Ku, Ying-Ren Wang, Hsuan-Yuan Lin, Shao-Chun Lu, Jung-Yaw Lin

published 15 May 2015

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Loss of Serglycin Promotes Primary Tumor Growth and Vessel Functionality in the RIP1-Tag2 Mouse Model for Spontaneous Insulinoma Formation

Andrew Hamilton, Vladimir Basic, Sandra Andersson, Magnus Abrink, Maria Ringvall

published 15 May 2015

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Health Effects of Long-Term Rapamycin Treatment: The Impact on Mouse Health of Enteric Rapamycin Treatment from Four Months of Age throughout Life

Kathleen E. Fischer, Jonathan A. L. Gelfond, Vanessa Y. Soto, Chul Han, Shinichi Someya, Arlan Richardson, Steven N. Austad

published 15 May 2015

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Lactobacillus fermentum ZYL0401 Attenuates Lipopolysaccharide-Induced Hepatic TNF-α Expression and Liver Injury via an IL-10- and PGE₂-EP4-Dependent Mechanism

Pengfeng Jin, Yunbo Chen, Longxian Lv, Jianzhuan Yang, Haifeng Lu, Lanjuan Li

published 15 May 2015

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Wild Type Mesenchymal Cells Contribute to the Lung Pathology of Lymphangioleiomyomatosis

Debbie Clements, Arundhati Dongre, Vera P. Krymskaya, Simon R. Johnson

published 15 May 2015

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Silica Triggers Inflammation and Ectopic Lymphoid Neogenesis in the Lungs in Parallel with Accelerated Onset of Systemic Autoimmunity and Glomerulonephritis in the Lupus-Prone NZBWF1 Mouse

Melissa A. Bates, Christina Brandenberger, Ingeborg Langohr, Kazuyoshi Kumagai, Jack R. Harkema, Andrij Holian, James J. Pestka

published 15 May 2015

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The HSP90 Inhibitor Ganetespib Alleviates Disease Progression and Augments Intermittent Cyclophosphamide Therapy in the MRL/lpr Mouse Model of Systemic Lupus Erythematosus

Yuan Liu, Josephine Ye, Luisa Shin Ogawa, Takayo Inoue, Qin Huang, John Chu, Richard C. Bates, Weiwen Ying, Andrew J. Sonderfan, Patricia E. Rao, Dan Zhou

published 14 May 2015

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Francisella tularensis Vaccines Elicit Concurrent Protective T- and B-Cell Immune Responses in BALB/cByJ Mice

Roberto De Pascalis, Lara Mittereder, Alicia Y. Chou, Nikki J. Kennett, Karen L. Elkins

published 14 May 2015

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Diacylglycerol O-Acyltransferase Type-1 Synthesizes Retinyl Esters in the Retina and Retinal Pigment Epithelium

Joanna J. Kaylor, Roxana A. Radu, Nicholas Bischoff, Jacob Makshanoff, Jane Hu, Marcia Lloyd, Shannan Eddington, Tran Bianconi, Dean Bok, Gabriel H. Travis

published 14 May 2015

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