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Mouse models

Sortase Enzyme-Mediated Generation of Site-Specifically Conjugated Antibody Drug Conjugates with High In Vitro and In Vivo Potency

Roger R. Beerli, Tamara Hell, Anna S. Merkel, Ulf Grawunder

published 01 Jul 2015

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Nisin ZP, a Bacteriocin and Food Preservative, Inhibits Head and Neck Cancer Tumorigenesis and Prolongs Survival

Pachiyappan Kamarajan, Takayuki Hayami, Bibiana Matte, Yang Liu, Theodora Danciu, Ayyalusamy Ramamoorthy, Francis Worden, Sunil Kapila, Yvonne Kapila

published 01 Jul 2015

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PET/CT Based In Vivo Evaluation of ⁶⁴Cu Labelled Nanodiscs in Tumor Bearing Mice

Pie Huda, Tina Binderup, Martin Cramer Pedersen, Søren Roi Midtgaard, Dennis Ringkjøbing Elema, Andreas Kjær, Mikael Jensen, Lise Arleth

published 01 Jul 2015

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Conditional Deletion of TAK1 in T Cells Reveals a Pivotal Role of TCRαβ⁺ Intraepithelial Lymphocytes in Preventing Lymphopenia-Associated Colitis

Hideki Sanjo, Shigeo Tokumaru, Shizuo Akira, Shinsuke Taki

published 01 Jul 2015

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Proliferation-Independent Initiation of Biliary Cysts in Polycystic Liver Diseases

Jean-Bernard Beaudry, Sabine Cordi, Céline Demarez, Sébastien Lepreux, Christophe E. Pierreux, Frédéric P. Lemaigre

published 30 Jun 2015

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The Sbi Protein Contributes to Staphylococcus aureus Inflammatory Response during Systemic Infection

Cintia Daniela Gonzalez, Camila Ledo, Constanza Giai, Ailin Garófalo, Marisa I. Gómez

published 30 Jun 2015

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Galectin-8 Ameliorates Murine Autoimmune Ocular Pathology and Promotes a Regulatory T Cell Response

James F. Sampson, Eiichi Hasegawa, Lama Mulki, Amol Suryawanshi, Shuhong Jiang, Wei-Sheng Chen, Gabriel A. Rabinovich, Kip M. Connor, Noorjahan Panjwani

published 30 Jun 2015

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miR-155 Controls Lymphoproliferation in LAT Mutant Mice by Restraining T-Cell Apoptosis via SHIP-1/mTOR and PAK1/FOXO3/BIM Pathways

Alexandre K. Rouquette-Jazdanian, Robert L. Kortum, Wenmei Li, Robert K. Merrill, Phan H. Nguyen, Lawrence E. Samelson, Connie L. Sommers

published 29 Jun 2015

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Immunization with an ApoB-100 Related Peptide Vaccine Attenuates Angiotensin-II Induced Hypertension and Renal Fibrosis in Mice

Tomoyuki Honjo, Kuang-Yuh Chyu, Paul C. Dimayuga, Wai Man Lio, Juliana Yano, Portia Trinidad, Xiaoning Zhao, Jianchang Zhou, Bojan Cercek, Prediman K. Shah

published 29 Jun 2015

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Decoy Receptor 3 Improves Survival in Experimental Sepsis by Suppressing the Inflammatory Response and Lymphocyte Apoptosis

DongYu Liang, YanQiang Hou, XiaoLi Lou, HongWei Chen

published 29 Jun 2015

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Truncating Homozygous Mutation of Carboxypeptidase E (CPE) in a Morbidly Obese Female with Type 2 Diabetes Mellitus, Intellectual Disability and Hypogonadotrophic Hypogonadism

Suzanne I. M. Alsters, Anthony P. Goldstone, Jessica L. Buxton, Anna Zekavati, Alona Sosinsky, Andrianos M. Yiorkas, Susan Holder, Robert E. Klaber, Nicola Bridges, Mieke M. van Haelst, Carel W. le Roux, Andrew J. Walley, Robin G. Walters, Michael Mueller, Alexandra I. F. Blakemore

published 29 Jun 2015

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Channel Activity of Cardiac Ryanodine Receptors (RyR2) Determines Potency and Efficacy of Flecainide and R-Propafenone against Arrhythmogenic Calcium Waves in Ventricular Cardiomyocytes

Eleonora Savio-Galimberti, Björn C. Knollmann

published 29 Jun 2015

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Altered Interactions between the Gut Microbiome and Colonic Mucosa Precede Polyposis in APC^Min/+ Mice

Joshua S. Son, Shanawaj Khair, Donald W. Pettet III, Nengtai Ouyang, Xinyu Tian, Yuanhao Zhang, Wei Zhu, Gerardo G. Mackenzie, Charles E. Robertson, Diana Ir, Daniel N. Frank, Basil Rigas, Ellen Li

published 29 Jun 2015

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