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Mouse models

Prostaglandin E2 and Transforming Growth Factor-β Play a Critical Role in Suppression of Allergic Airway Inflammation by Adipose-Derived Stem Cells

Kyu-Sup Cho, Jung-Hoon Lee, Mi-Kyung Park, Hye-Kyung Park, Hak-Sun Yu, Hwan-Jung Roh

published 15 Jul 2015

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Impaired Itching Perception in Murine Models of Cholestasis Is Supported by Dysregulation of GPBAR1 Signaling

Sabrina Cipriani, Barbara Renga, Claudio D’Amore, Michele Simonetti, Antonio Angelo De Tursi, Adriana Carino, Maria Chiara Monti, Valentina Sepe, Angela Zampella, Stefano Fiorucci

published 15 Jul 2015

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IGF1R- and ROR1-Specific CAR T Cells as a Potential Therapy for High Risk Sarcomas

Xin Huang, Haein Park, Joseph Greene, James Pao, Erin Mulvey, Sophia X. Zhou, Catherine M. Albert, Fred Moy, Deepali Sachdev, Douglas Yee, Christoph Rader, Carl V. Hamby, David M. Loeb, Mitchell S. Cairo, Xianzheng Zhou

published 14 Jul 2015

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TGF-β Blockade Reduces Mortality and Metabolic Changes in a Validated Murine Model of Pancreatic Cancer Cachexia

Stephanie H. Greco, Lena Tomkötter, Anne-Kristin Vahle, Rae Rokosh, Antonina Avanzi, Syed Kashif Mahmood, Michael Deutsch, Sara Alothman, Dalia Alqunaibit, Atsuo Ochi, Constantinos Zambirinis, Tasnima Mohaimin, Mauricio Rendon, Elliot Levie, Mridul Pansari, Alejandro Torres-Hernandez, Donnele Daley, Rocky Barilla, H. Leon Pachter, Daniel Tippens, Hassan Malik, Allal Boutajangout, Thomas Wisniewski, George Miller

published 14 Jul 2015

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Altered CSMD1 Expression Alters Cocaine-Conditioned Place Preference: Mutual Support for a Complex Locus from Human and Mouse Models

Jana Drgonova, Donna Walther, Sulabh Singhal, Kennedy Johnson, Brice Kessler, Juan Troncoso, George R. Uhl

published 14 Jul 2015

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Tissue Inhibitor Of Matrix Metalloproteinase-1 Is Required for High-Fat Diet-Induced Glucose Intolerance and Hepatic Steatosis in Mice

Even Fjære, Charlotte Andersen, Lene Secher Myrmel, Rasmus Koefoed Petersen, Jakob Bondo Hansen, Hanne Sørup Tastesen, Thomas Mandrup-Poulsen, Nils Brünner, Karsten Kristiansen, Lise Madsen, Maria Unni Rømer

published 13 Jul 2015

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Tacrolimus Protects Podocytes from Injury in Lupus Nephritis Partly by Stabilizing the Cytoskeleton and Inhibiting Podocyte Apoptosis

Ruyi Liao, Qinghua Liu, Zhihua Zheng, Jinjin Fan, Wenxing Peng, Qingyu Kong, Huijuan He, Shicong Yang, Wenfang Chen, Xueqing Tang, Xueqing Yu

published 10 Jul 2015

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Cyclin Y Is Involved in the Regulation of Adipogenesis and Lipid Production

Weiwei An, Zhuzhen Zhang, Liyong Zeng, Ying Yang, Xueliang Zhu, Jiarui Wu

published 10 Jul 2015

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Optimization of an Image-Guided Laser-Induced Choroidal Neovascularization Model in Mice

Yan Gong, Jie Li, Ye Sun, Zhongjie Fu, Chi-Hsiu Liu, Lucy Evans, Katherine Tian, Nicholas Saba, Thomas Fredrick, Peyton Morss, Jing Chen, Lois E. H. Smith

published 10 Jul 2015

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Characterization of Novel Src Family Kinase Inhibitors to Attenuate Microgliosis

Gunjan D. Manocha, Kendra L. Puig, Susan A. Austin, Kathleen Seyb, Marcie A. Glicksman, Colin K. Combs

published 10 Jul 2015

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Non-Lethal Ionizing Radiation Promotes Aging-Like Phenotypic Changes of Human Hematopoietic Stem and Progenitor Cells in Humanized Mice

Changshan Wang, Motohiko Oshima, Goro Sashida, Takahisa Tomioka, Nagisa Hasegawa, Makiko Mochizuki-Kashio, Yaeko Nakajima-Takagi, Yoichiro Kusunoki, Seishi Kyoizumi, Kazue Imai, Kei Nakachi, Atsushi Iwama

published 10 Jul 2015

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The Goblet Cell Protein Clca1 (Alias mClca3 or Gob-5) Is Not Required for Intestinal Mucus Synthesis, Structure and Barrier Function in Naive or DSS-Challenged Mice

Nancy A. Erickson, Elisabeth E. L. Nyström, Lars Mundhenk, Liisa Arike, Rainer Glauben, Markus M. Heimesaat, André Fischer, Stefan Bereswill, George M. H. Birchenough, Achim D. Gruber, Malin E. V. Johansson

published 10 Jul 2015

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Alterations in Hippocampal Oxidative Stress, Expression of AMPA Receptor GluR2 Subunit and Associated Spatial Memory Loss by Bacopa monnieri Extract (CDRI-08) in Streptozotocin-Induced Diabetes Mellitus Type 2 Mice

Surya P. Pandey, Hemant K. Singh, S. Prasad

published 10 Jul 2015

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