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Mouse models

Heparan Sulfate Biosynthesis Enzyme, Ext1, Contributes to Outflow Tract Development of Mouse Heart via Modulation of FGF Signaling

Rui Zhang, Peijuan Cao, Zhongzhou Yang, Zhenzhen Wang, Jiu-Lin Wu, Yan Chen, Yi Pan

published 21 Aug 2015

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Potential Therapeutic Effect of Natural Killer Cells on Doxorubicin-Resistant Breast Cancer Cells In Vitro

Mi-Hye Hwang, Xiu Juan Li, Jung Eun Kim, Shin Young Jeong, Sang-Woo Lee, Jaetae Lee, Byeong-Cheol Ahn

published 21 Aug 2015

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Comparative Analysis of Two Gene-Targeting Approaches Challenges the Tumor-Suppressive Role of the Protein Kinase MK5/PRAK

Natalia Ronkina, Claus Johansen, Lisa Bohlmann, Juri Lafera, Manoj B. Menon, Christopher Tiedje, Kathrin Laaß, Benjamin E. Turk, Lars Iversen, Alexey Kotlyarov, Matthias Gaestel

published 21 Aug 2015

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Creation of Mice Bearing a Partial Duplication of HPRT Gene Marked with a GFP Gene and Detection of Revertant Cells In Situ as GFP-Positive Somatic Cells

Asao Noda, Hirofumi Suemori, Yuko Hirai, Kanya Hamasaki, Yoshiaki Kodama, Hiroshi Mitani, Reid D. Landes, Nori Nakamura

published 21 Aug 2015

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Genetic and Informatic Analyses Implicate Kif12 as a Candidate Gene within the Mpkd2 Locus That Modulates Renal Cystic Disease Severity in the Cys1cpk Mouse

Michal Mrug, Juling Zhou, Chaozhe Yang, Bruce J. Aronow, Xiangqin Cui, Trenton R. Schoeb, Gene P. Siegal, Bradley K Yoder, Lisa M. Guay-Woodford

published 21 Aug 2015

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Hdh^Q111 Mice Exhibit Tissue Specific Metabolite Profiles that Include Striatal Lipid Accumulation

Jeffrey B. Carroll, Amy Deik, Elisa Fossale, Rory M. Weston, Jolene R. Guide, Jamshid Arjomand, Seung Kwak, Clary B. Clish, Marcy E. MacDonald

published 21 Aug 2015

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Generation of a Tph2 Conditional Knockout Mouse Line for Time- and Tissue-Specific Depletion of Brain Serotonin

Barbara Pelosi, Marta Pratelli, Sara Migliarini, Giulia Pacini, Massimo Pasqualetti

published 20 Aug 2015

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An Efficient and Versatile System for Visualization and Genetic Modification of Dopaminergic Neurons in Transgenic Mice

Karsten Tillack, Helia Aboutalebi, Edgar R. Kramer

published 20 Aug 2015

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Chromosome Condensation 1-Like (Chc1L) Is a Novel Tumor Suppressor Involved in Development of Histiocyte-Rich Neoplasms

David R. Spillane, Ding Yan Wang, Susan Newbigging, Youdong Wang, Chang-Xin Shi, Hae-Ra Cho, Hiroki Shimizu, Anthony Gramolini, Mingyao Liu, Xiao-Yan Wen

published 20 Aug 2015

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Molecular Design of Bisphosphonate-Modified Proteins for Efficient Bone Targeting In Vivo

Hidemasa Katsumi, Jun-ichi Sano, Makiya Nishikawa, Keiko Hanzawa, Toshiyasu Sakane, Akira Yamamoto

published 19 Aug 2015

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Guanabenz Treatment Accelerates Disease in a Mutant SOD1 Mouse Model of ALS

Fernando G. Vieira, Qinggong Ping, Andy J. Moreno, Joshua D. Kidd, Kenneth Thompson, Bingbing Jiang, John M. Lincecum, Monica Z. Wang, Gerard S. De Zutter, Valerie R. Tassinari, Beth Levine, Theo Hatzipetros, Alan Gill, Steven Perrin

published 19 Aug 2015

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Genetic Ablation of CD38 Protects against Western Diet-Induced Exercise Intolerance and Metabolic Inflexibility

Shian-Huey Chiang, W. Wallace Harrington, Guizhen Luo, Naphtali O. Milliken, John C. Ulrich, Jing Chen, Deepak K. Rajpal, Ying Qian, Tiffany Carpenter, Rusty Murray, Robert S. Geske, Stephen A. Stimpson, Henning F. Kramer, Curt D. Haffner, J. David Becherer, Frank Preugschat, Andrew N. Billin

published 19 Aug 2015

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Monoacylglycerol Lipase Regulates Fever Response

Manuel Sanchez-Alavez, William Nguyen, Simone Mori, Gianluca Moroncini, Andreu Viader, Daniel K. Nomura, Benjamin F. Cravatt, Bruno Conti

published 19 Aug 2015

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