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Mouse models

Suppression of Locomotor Activity in Female C57Bl/6J Mice Treated with Interleukin-1β: Investigating a Method for the Study of Fatigue in Laboratory Animals

David R. Bonsall, Hyunji Kim, Catherine Tocci, Awa Ndiaye, Abbey Petronzio, Grace McKay-Corkum, Penny C. Molyneux, Thomas E. Scammell, Mary E. Harrington

published 15 Oct 2015

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Increased Cortical Inhibition in Autism-Linked Neuroligin-3R451C Mice Is Due in Part to Loss of Endocannabinoid Signaling

Haley E. Speed, Irene Masiulis, Jay R. Gibson, Craig M. Powell

published 15 Oct 2015

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Fractalkine Signaling Regulates the Inflammatory Response in an α-Synuclein Model of Parkinson Disease

Aaron D. Thome, David G. Standaert, Ashley S. Harms

published 15 Oct 2015

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The Effects of CFTR and Mucoid Phenotype on Susceptibility and Innate Immune Responses in a Mouse Model of Pneumococcal Lung Disease

Evida A. Dennis, Mamie T. Coats, Sarah E. Griffin, Joanetha Y. Hale, Lea Novak, David E. Briles, Marilyn J. Crain

published 15 Oct 2015

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Edaravone, a Free Radical Scavenger, Delayed Symptomatic and Pathological Progression of Motor Neuron Disease in the Wobbler Mouse

Ken Ikeda, Yasuo Iwasaki

published 15 Oct 2015

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Deletion of IL-18 Expression Ameliorates Spontaneous Kidney Failure in MRL^lpr Mice

Bastian Schirmer, Dirk Wedekind, Silke Glage, Detlef Neumann

published 14 Oct 2015

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Transmissibility of H-Type Bovine Spongiform Encephalopathy to Hamster PrP Transgenic Mice

Hiroyuki Okada, Kentaro Masujin, Kohtaro Miyazawa, Takashi Yokoyama

published 14 Oct 2015

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Natural Killer Cells Improve Hematopoietic Stem Cell Engraftment by Increasing Stem Cell Clonogenicity In Vitro and in a Humanized Mouse Model

Michelle Escobedo-Cousin, Nicola Jackson, Raquel Laza-Briviesca, Linda Ariza-McNaughton, Martha Luevano, Sophie Derniame, Sergio Querol, Michael Blundell, Adrian Thrasher, Bernat Soria, Nichola Cooper, Dominique Bonnet, Alejandro Madrigal, Aurore Saudemont

published 14 Oct 2015

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CNF1 Enhances Brain Energy Content and Counteracts Spontaneous Epileptiform Phenomena in Aged DBA/2J Mice

Sara Travaglione, Giulia Ballan, Andrea Fortuna, Alberto Ferri, Marco Guidotti, Gabriele Campana, Carla Fiorentini, Stefano Loizzo

published 12 Oct 2015

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Wild-Type Hras Suppresses the Earliest Stages of Tumorigenesis in a Genetically Engineered Mouse Model of Pancreatic Cancer

Jamie D. Weyandt, Benjamin L. Lampson, Sherry Tang, Matthew Mastrodomenico, Diana M. Cardona, Christopher M. Counter

published 09 Oct 2015

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Klotho Protects Dopaminergic Neuron Oxidant-Induced Degeneration by Modulating ASK1 and p38 MAPK Signaling Pathways

Reynolds K. Brobey, Dwight German, Patricia K. Sonsalla, Prem Gurnani, Johanne Pastor, C-C Hsieh, John Papaconstantinou, Philip P. Foster, Makoto Kuro-o, Kevin P. Rosenblatt

published 09 Oct 2015

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Smooth Muscle-Targeted Overexpression of Peroxisome Proliferator Activated Receptor-γ Disrupts Vascular Wall Structure and Function

Jennifer M. Kleinhenz, Tamara C. Murphy, Anastassia P. Pokutta-Paskaleva, Rudolph L. Gleason, Alicia N. Lyle, W. Robert Taylor, Mitsi A. Blount, Juan Cheng, Qinglin Yang, Roy L. Sutliff, C. Michael Hart

published 09 Oct 2015

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Lack of Cytosolic Carboxypeptidase 1 Leads to Subfertility due to the Reduced Number of Antral Follicles in pcd3J-/- Females

Ning Song, Nameun Kim, Rui Xiao, Hojun Choi, Hyo-Im Chun, Min-Hee Kang, Jin-Hoi Kim, Kunho Seo, Nagasundarapandian Soundrarajan, Jeong-Tae Do, Hyuk Song, Zhao-Jia Ge, Chankyu Park

published 09 Oct 2015

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