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Mouse models

Discovery and Characterization of a Potent Interleukin-6 Binding Peptide with Neutralizing Activity In Vivo

Sheila Ranganath, Ashok Bhandari, Nicole Avitahl-Curtis, Jaimee McMahon, Derek Wachtel, Jenny Zhang, Christopher Leitheiser, Sylvie G. Bernier, Guang Liu, Tran T. Tran, Herodion Celino, Jenny Tobin, Joon Jung, Hong Zhao, Katie E. Glen, Chris Graul, Aliesha Griffin, Wayne C. Schairer, Carolyn Higgins, Tammi L. Reza, Eva Mowe, Sam Rivers, Sonya Scott, Alex Monreal, Courtney Shea, Greg Bourne, Casey Coons, Adaline Smith, Kim Tang, Ramya A. Mandyam, Jaime Masferrer, David Liu, Dinesh V. Patel, Angelika Fretzen, Craig A. Murphy, G. Todd Milne, Mark L. Smythe, Kenneth E. Carlson

published 10 Nov 2015

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Progression of Alport Kidney Disease in Col4a3 Knock Out Mice Is Independent of Sex or Macrophage Depletion by Clodronate Treatment

Munkyung Kim, Alessandro Piaia, Neeta Shenoy, David Kagan, Berangere Gapp, Benjamin Kueng, Delphine Weber, William Dietrich, Iwona Ksiazek

published 10 Nov 2015

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Missense Mutations in LRP5 Associated with High Bone Mass Protect the Mouse Skeleton from Disuse- and Ovariectomy-Induced Osteopenia

Paul J. Niziolek, Whitney Bullock, Matthew L. Warman, Alexander G. Robling

published 10 Nov 2015

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Merkel Cell Polyomavirus Small T Antigen Induces Cancer and Embryonic Merkel Cell Proliferation in a Transgenic Mouse Model

Masahiro Shuda, Anna Guastafierro, Xuehui Geng, Yoko Shuda, Stephen M. Ostrowski, Stefan Lukianov, Frank J. Jenkins, Kord Honda, Stephen M. Maricich, Patrick S. Moore, Yuan Chang

published 06 Nov 2015

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Differential Effects of C1qa Ablation on Glaucomatous Damage in Two Sexes in DBA/2NNia Mice

Ruma Kumari, Konstantin Astafurov, Alina Genis, John Danias

published 06 Nov 2015

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IRF4-Dependent and IRF4-Independent Pathways Contribute to DC Dysfunction in Lupus

Michela Manni, Sanjay Gupta, Briana G. Nixon, Casey T. Weaver, Rolf Jessberger, Alessandra B. Pernis

published 06 Nov 2015

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The Anti-Tumor Activity of Succinyl Macrolactin A Is Mediated through the β-Catenin Destruction Complex via the Suppression of Tankyrase and PI3K/Akt

Sushil C. Regmi, Su Young Park, Seung Joo Kim, Suhrid Banskota, Sajita Shah, Dong-Hee Kim, Jung-Ae Kim

published 06 Nov 2015

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Lysine Methylation of the Valosin-Containing Protein (VCP) Is Dispensable for Development and Survival of Mice

Markus Fusser, Stefan Kernstock, Vinay Kumar Aileni, Wolfgang Egge-Jacobsen, Pål Ø. Falnes, Arne Klungland

published 06 Nov 2015

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Sonic Hedgehog Signaling: Evidence for Its Protective Role in Endotoxin Induced Acute Lung Injury in Mouse Model

Xing Chen, Yuting Jin, Xiaoming Hou, Fengqin Liu, Yulin Wang

published 06 Nov 2015

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Anthocyanin Extracted from Black Soybean Seed Coats Prevents Autoimmune Arthritis by Suppressing the Development of Th17 Cells and Synthesis of Proinflammatory Cytokines by Such Cells, via Inhibition of NF-κB

Hong Ki Min, Sung-Min Kim, Seung-Ye Baek, Jung-Won Woo, Jin-Sil Park, Mi-La Cho, Jennifer Lee, Seung-Ki Kwok, Sae Woong Kim, Sung-Hwan Park

published 06 Nov 2015

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Tumor Volume Estimation and Quasi-Continuous Administration for Most Effective Bevacizumab Therapy

Johanna Sápi, Levente Kovács, Dániel András Drexler, Pál Kocsis, Dávid Gajári, Zoltán Sápi

published 05 Nov 2015

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Antagonistic Regulation of Parvalbumin Expression and Mitochondrial Calcium Handling Capacity in Renal Epithelial Cells

Thomas Henzi, Beat Schwaller

published 05 Nov 2015

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Development of a Novel PET Tracer [¹⁸F]AlF-NOTA-C6 Targeting MMP2 for Tumor Imaging

Qinghua Liu, Donghui Pan, Chao Cheng, Dazhi Zhang, Anyu Zhang, Lizhen Wang, Hongdie Jiang, Tao Wang, Hongrui Liu, Yuping Xu, Runlin Yang, Fei Chen, Min Yang, Changjing Zuo

published 05 Nov 2015

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