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Mouse models

Therapeutic potential of archaeal unfoldase PAN^et and the gateless T20S proteasome in P23H rhodopsin retinitis pigmentosa mice

Celine Brooks, Douglas Kolson, [ ... ], Maxim Sokolov

PD1CD28 chimeric molecule enhances EGFRvⅢ specific CAR-T cells in xenograft experiments in mouse models

Wanqiong Chen, Na Xian, [ ... ], Yunlu Xu

Vaginal Tritrichomonas foetus infection in mice as an in vivo model for drug development against Trichomonas vaginalis

Noelle M. Nieskens, Yukiko Miyamoto, [ ... ], Lars Eckmann

Efficacy of mefloquine and its enantiomers in a murine model of Mycobacterium avium infection

Antoine Froment, Julia Delomez, [ ... ], Jean-Philippe Lanoix

Proteomic analysis of dorsal root ganglia in a mouse model of paclitaxel-induced neuropathic pain

Rania Hanna, Alexandru Graur, [ ... ], Nadine Kabbani

Aerobic exercise up-regulates Klotho to improve renal fibrosis associated with aging and its mechanism

Jinfeng Zhao, Yue Guan, [ ... ], Yue Cai

The heat shock protein 90 inhibitor RGRN-305 attenuates SARS-CoV-2 spike protein-induced inflammation in vitro but lacks effectiveness as COVID-19 treatment in mice

Hakim Ben Abdallah, Giorgia Marino, [ ... ], Claus Johansen

Pharmacological intervention of behavioural traits and brain histopathology of prenatal valproic acid-induced mouse model of autism

Sharmind Neelotpol, Rifat Rezwan, [ ... ], Mohd Raeed Jamiruddin

Matrix metalloproteinases mediate influenza A-associated shedding of the alveolar epithelial glycocalyx

Kaitlyn R. Schaaf, Stuart R. Landstreet, [ ... ], Ciara M. Shaver

Water extract of ginseng alleviates parkinsonism in MPTP–induced Parkinson’s disease mice

Ning Xu, Shuyang Xing, [ ... ], Yu Zhao

Distribution of MRI-derived T2 values as a biomarker for in vivo rapid screening of phenotype severity in mdx mice

Emily A. Waters, Chad R. Haney, [ ... ], Alexis R. Demonbreun

Berberine potentiates liver inflammation and fibrosis in the PI*Z hAAT transgenic murine model

Yuanqing Lu, Naweed S. Mohammad, [ ... ], Mark L. Brantly

Targeting ferroptosis with the lipoxygenase inhibitor PTC-041 as a therapeutic strategy for the treatment of Parkinson’s disease

Angela Minnella, Kevin P. McCusker, [ ... ], Jeffrey K. Trimmer

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