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Mouse models

Integrated multi-omics approach revealed TTNtv c.13254T>G causing dilated cardiomyopathy in mice

Dan Yu, Liang Tao, Laichun Song, Kaisheng Lai, Hui Jiang, Zhe Liu, Hongyan Xiao

published 04 Oct 2024

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Functional comparison of human and murine equilibrative nucleobase transporter 1

Chan S. Kim, Aaron L. Sayler, Hannah Dean, Nicholas M. Ruel, James R. Hammond

published 03 Oct 2024

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Therapeutic potential of archaeal unfoldase PAN^et and the gateless T20S proteasome in P23H rhodopsin retinitis pigmentosa mice

Celine Brooks, Douglas Kolson, Emily Sechrest, Janelle Chuah, Jane Schupp, Neil Billington, Wen-Tao Deng, David Smith, Maxim Sokolov

published 03 Oct 2024

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PD1CD28 chimeric molecule enhances EGFRvⅢ specific CAR-T cells in xenograft experiments in mouse models

Wanqiong Chen, Na Xian, Ningning Zhao, Qiong Zhang, Yunlu Xu

published 01 Oct 2024

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Vaginal Tritrichomonas foetus infection in mice as an in vivo model for drug development against Trichomonas vaginalis

Noelle M. Nieskens, Yukiko Miyamoto, Brianna M. Hurysz, Anthony J. O’Donoghue, Lars Eckmann

published 01 Oct 2024

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Efficacy of mefloquine and its enantiomers in a murine model of Mycobacterium avium infection

Antoine Froment, Julia Delomez, Sophie Da Nascimento, Alexandra Dassonville-Klimpt, Claire Andréjak, François Peltier, Cédric Joseph, Pascal Sonnet, Jean-Philippe Lanoix

published 30 Sep 2024

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Proteomic analysis of dorsal root ganglia in a mouse model of paclitaxel-induced neuropathic pain

Rania Hanna, Alexandru Graur, Patricia Sinclair, Bryan D. Mckiver, Paula D. Bos, M. Imad Damaj, Nadine Kabbani

published 27 Sep 2024

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Aerobic exercise up-regulates Klotho to improve renal fibrosis associated with aging and its mechanism

Jinfeng Zhao, Yue Guan, Yingxiu Jia, Yinghua Chen, Yue Cai

published 26 Sep 2024

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The heat shock protein 90 inhibitor RGRN-305 attenuates SARS-CoV-2 spike protein-induced inflammation in vitro but lacks effectiveness as COVID-19 treatment in mice

Hakim Ben Abdallah, Giorgia Marino, Manja Idorn, Line S. Reinert, Anne Bregnhøj, Søren Riis Paludan, Claus Johansen

published 26 Sep 2024

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Pharmacological intervention of behavioural traits and brain histopathology of prenatal valproic acid-induced mouse model of autism

Sharmind Neelotpol, Rifat Rezwan, Timothy Singh, Iffat Islam Mayesha, Sayedatus Saba, Mohd Raeed Jamiruddin

published 24 Sep 2024

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Matrix metalloproteinases mediate influenza A-associated shedding of the alveolar epithelial glycocalyx

Kaitlyn R. Schaaf, Stuart R. Landstreet, Nathan D. Putz, Samantha K. Gonski, Jason Lin, Charity J. Buggs, Dustin Gibson, Christophe J. Langouët-Astrié, Christopher S. Jetter, Nicolas M. Negretti, Jennifer M. S. Sucre, Eric P. Schmidt, Lorraine B. Ware, Julie A. Bastarache, Ciara M. Shaver

published 23 Sep 2024

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Water extract of ginseng alleviates parkinsonism in MPTP–induced Parkinson’s disease mice

Ning Xu, Shuyang Xing, Jie Li, Bo Pang, Meichen Liu, Meiling Fan, Yu Zhao

published 20 Sep 2024

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Distribution of MRI-derived T2 values as a biomarker for in vivo rapid screening of phenotype severity in mdx mice

Emily A. Waters, Chad R. Haney, Lauren A Vaught, Elizabeth M. McNally, Alexis R. Demonbreun

published 19 Sep 2024

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