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Mouse models

Tracking inflammation resolution signatures in lungs after SARS-CoV-2 omicron BA.1 infection of K18-hACE2 mice

Agnes Carolin, Kexin Yan, Cameron R. Bishop, Bing Tang, Wilson Nguyen, Daniel J. Rawle, Andreas Suhrbier

published 12 Nov 2024

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RTA408 alleviates retinal ganglion cells damage in mouse glaucoma by inhibiting excessive autophagy

Hongmei Qian, Wei Chen, Guomei Yuan, Man Luo, Li Zhang, Biao Wu, Hanshi Huang, Jiahao Xu, Qiong Wang, Mengyun Li

published 11 Nov 2024

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Systemic analysis shows that cold exposure modulates triglyceride accumulation and phospholipid distribution in mice

Isabella James, Raghav Jain, Gina Wade, Philip C. Stevenson, Albert Koulman, Judith Simcox, Samuel Furse

published 07 Nov 2024

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n-Butylidenephthalide recovered calcium homeostasis to ameliorate neurodegeneration of motor neurons derived from amyotrophic lateral sclerosis iPSCs

Yu-Chen Deng, Jen-Wei Liu, Hsiao-Chien Ting, Tzu-Chen Kuo, Chia-Hung Chiang, En-Yi Lin, Horng-Jyh Harn, Shinn-Zong Lin, Chia-Yu Chang, Tzyy-Wen Chiou

published 07 Nov 2024

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Early expression of osteopontin glycoprotein on the ocular surface and in tear fluid contributes to ocular surface diseases in type 2 diabetic mice

Ananya Datta, Xin Yi Li, Manshul Nagpaul

published 31 Oct 2024

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(−)-Epicatechin regulates endoplasmic reticulum stress and promotes ferroptosis in lung cancer cells via the PERK/eIF2α/ATF4 signaling pathway

Zengbo Lv, Peiwan Liu, Yingyu Yang, Jianhua Ji, Anao Wu, Wensheng Huang, Liqiong Zhang, Zhijun Zhang, Yunkui Yang, Wenhui Li, Meifang Huang

published 31 Oct 2024

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Evaluation of variation in preclinical electroencephalographic (EEG) spectral power across multiple laboratories and experiments: An EQIPD study

Tim P. Ahuis, Magdalena K. Smyk, Clément Laloux, Katharina Aulehner, Jack Bray, Ann-Marie Waldron, Nina Miljanovic, Isabel Seiffert, Dekun Song, Bruno Boulanger, Mathias Jucker, Heidrun Potschka, Bettina Platt, Gernot Riedel, Patrizia Voehringer, Janet R. Nicholson, Wilhelmus H. I. M. Drinkenburg, Martien J. H. Kas, Steven C. Leiser

published 29 Oct 2024

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Fecal microbiota transplantation from protozoa-exposed donors downregulates immune response in a germ-free mouse model, its role in immune response and physiology of the intestine

Oswaldo Partida-Rodríguez, Eric M. Brown, Sarah E. Woodward, Mihai Cirstea, Lisa A. Reynolds, Charisse Petersen, Stefanie L. Vogt, Jorge Peña-Díaz, Lisa Thorson, Marie-Claire Arrieta, Eric G. Hernández, Liliana Rojas-Velázquez, Patricia Moran, Enrique González Rivas, Angélica Serrano-Vázquez, Horacio Pérez-Juárez, Javier Torres, Cecilia Ximénez, B. B. Finlay

published 28 Oct 2024

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Effects of Artemisia asiatica ex on Akkermansia muciniphila dominance for modulation of Alzheimer’s disease in mice

Mijung Lee, Kwang-Sung Ahn, Manho Kim

published 28 Oct 2024

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The protective effect and immunomodulatory ability of orally administrated Lacticaseibacillus rhamnosus GG against Mycoplasma pneumoniae infection in BALB/c mice

Huanbing Long, Guiting He, Jiarong He, Ting feng Du, Pengxiao Feng, Cuiming Zhu

published 25 Oct 2024

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Evaluation of general anesthesia protocols for a highly controlled cardiac ischemia-reperfusion model in mice

Christelle Leon, Alice Ruelle, Juliette Geoffray, Lionel Augeul, Catherine Vogt, Pascal Chiari, Ludovic Gomez, Michel Ovize, Gabriel Bidaux, Bruno Pillot

published 25 Oct 2024

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The SWI/SNF subunit ARID1B is important for regenerative ability of hematopoietic stem cells in normal hematopoiesis

Olivia Arnold, Theresa Bluemn, Cary Stelloh, Sridhar Rao, Nan Zhu

published 24 Oct 2024

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Clinical validation of the suppressive impact of letrozole on liver fibrosis in patients with breast cancer undergoing continuous letrozole administration: A retrospective study

Kazuyoshi Ohkawa, Tasuku Nakabori, Kaori Mukai, Kazuhiro Kozumi, Makiko Urabe, Yugo Kai, Ryoji Takada, Kenji Ikezawa, Yuko Yamaguchi, Takuya Nagao, Hatsune Enomoto, Hidehisa Tachiki, Ayako Higuchi, Noriyuki Watanabe, Takahiro Nakayama

published 24 Oct 2024

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