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Mouse models

Exploring the feasibility of using mice as a substitute model for investigating microglia in aging and Alzheimer’s disease though single cell analysis

Rong He, Qiang Zhang, [ ... ], Xue Cao

Pine pollen reverses the function of hepatocellular carcinoma by inhibiting α-Enolase mediated PI3K/AKT signaling pathway

Yanhong Luo, Chun Guo, [ ... ], Weixin Xu

Single-cell sequencing reveals transcriptional dynamics regulated by ERα in mouse ovaries

Qicai Hu, Yiqian Gui, [ ... ], Huiru Tang

The probiotic Lacticaseibacillus rhamnosus SD11 alleviates the progression of liver and colon damage through modulation of inflammation and tight junction proteins in streptozotocin-induced diabetic mice

Waraporn Ruathong, Pissared Khuituan, [ ... ], Jongdee Nopparat

Negative effects of lifespan extending intervention on resilience in mice

Katelynn M. Corder, Jessica M. Hoffman, [ ... ], Steven N. Austad

Immune complex deposition promotes NK cell accumulation in the kidney

Abigail De la Cruz, Marco Garcés, [ ... ], Florencia Rosetti

Compound 4f, a novel brain-penetrant reversible monoacylglycerol inhibitor, ameliorates neuroinflammation, neuronal cell loss, and cognitive impairment in mice with kainic acid-induced neurodegeneration

Naoto Arimura, Chie Maeda, [ ... ], Maiko Tanaka

Development of a novel complex inflammatory bowel disease mouse model: Reproducing human inflammatory bowel disease etiologies in mice

Sun-Min Seo, Na-Won Kim, [ ... ], Yang-Kyu Choi

Gentiopicroside-Induced gastric cancer necroptosis via the HIF-1 signaling pathway: A study involving molecular docking and experimental validation

Bo Xiong, Mingjie Fan, [ ... ], Beibei Fan

Cardiac effects of OPA1 protein promotion in a transgenic animal model

Kitti Bruszt, Orsolya Horvath, [ ... ], Laszlo Deres

Inhibition of CCl₄-induced liver inflammation and fibrosis by a NEU3 inhibitor

Darrell Pilling, Trevor C. Martinez, Richard H. Gomer

Cyclophosphamide- and doxorubicin-induced impairment of high affinity choline uptake and spatial memory can be prevented by dietary choline supplementation in breast tumor bearing mice

Robert Botelho, Cheryl L. Kirstein, Rex M. Philpot

Prrx1-driven LINC complex disruption in vivo reduces osteoid deposition but not bone quality after voluntary wheel running

Scott Birks, Sean Howard, [ ... ], Gunes Uzer

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