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Mouse models

Podocyte specific knockout of the natriuretic peptide clearance receptor is podocyte protective in focal segmental glomerulosclerosis

Liming Wang, Yuping Tang, Anne F. Buckley, Robert F. Spurney

published 10 Mar 2025

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Kaempferia parviflora extract and its methoxyflavones as potential anti-Alzheimer assessing in vitro, integrated computational approach, and in vivo impact on behaviour in scopolamine-induced amnesic mice

Pitchayakarn Takomthong, Pornthip Waiwut, Chavi Yenjai, Jinda Wangboonskul, Kusawadee Plekratoke, Puguh Novi Arsito, Carlo Ballatore, Chantana Boonyarat

published 10 Mar 2025

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Mis-splicing drives loss of function of p53^E224D point mutation

Ian C. Lock, Nathan H. Leisenring, Warren Floyd, Eric S. Xu, Lixia Luo, Yan Ma, Erin C. Mansell, Diana M. Cardona, Chang-Lung Lee, David G. Kirsch

published 05 Mar 2025

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Retinal and thalamic alterations in the 5xFAD mouse model of Alzheimer’s disease

Shaylah McCool, Jennie C. Smith, Asia Sladek, Shan Fan, Matthew J. Van Hook

published 03 Mar 2025

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Implications of tissue specific STING protein flux and abundance on inflammation and the development of targeted therapeutics

Thomas E. Angel, Zhuo Chen, Ahmed Moghieb, Sze-Ling Ng, Allison M. Beal, Carol Capriotti, Leonard Azzarano, Debra Comroe, Michael Adam, Patrick Moore, Bao Hoang, Kelly Blough, Joanne Kuziw, Joshi M. Ramanjulu, G. Scott Pesiridis

published 25 Feb 2025

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Identification of suitable qPCR reference genes for the normalization of gene expression in the BL10-mdx and D2-mdx mouse models of Duchenne muscular dystrophy

Kayleigh Putker, Anne-Fleur Schneider, Davy Van De Vijver, John Hildyard, Annemieke Aartsma-Rus, Maaike van Putten

published 25 Feb 2025

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Differential expression and modulation of EBI2 and 7α,25-OHC synthesizing (CH25H, CYP7B1) and degrading (HSD3B7) enzymes in mouse and human brain vascular cells

Fionä Caratis, Bartosz Karaszewski, Ilona Klejbor, Tomomi Furihata, Aleksandra Rutkowska

published 25 Feb 2025

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Soluble RAGE enhances muscle regeneration after cryoinjury in aged and diseased mice

Naftali Horwitz, Michael Florea, K. C. Medha, Tina Liu, Vivian Garcia, Rebekah Kim, Amy Lam, Kathleen Messemer, Christopher Rios, Albert E. Almada, Amy J. Wagers

published 25 Feb 2025

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Delayed hepatic response and impaired cytokine dynamics in aged mice following burn injury: Implications for elderly patient care

Israel Muro, Andrea C. Qualman, Kenneth Meza Monge, Akshay Pratap, Elizabeth J. Kovacs, Juan-Pablo Idrovo

published 24 Feb 2025

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Sodium propionate decreases implant-induced foreign body response in mice

Deivenita Juliana Alves Carvalho do Carmo, Marcela Guimarães Takahashi Lazari, Letícia Cristine Cardoso dos Santos, Pedro Augusto Carvalho Costa, Itamar Couto Guedes Jesus, Silvia Guatimosim, Pedro Pires Goulart Guimaraes, Silvia Passos Andrade, Paula Peixoto Campos

published 19 Feb 2025

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Use of a mouse model for the isolation of Borrelia puertoricensis from soft ticks

Edwin Vázquez-Guerrero, Alexander R. Kneubehl, Guadalupe C. Reyes-Solís, Carlos Machain-Williams, Aparna Krishnavajhala, Paulina Estrada-de los Santos, Job E. Lopez, José Antonio Ibarra

published 18 Feb 2025

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The bone phenotype associated with cherubism is independent of Caspase-1-dependent inflammasome activation in the mouse

Badre-Victor Rabhi, Sylvie Thomasseau, Xavier Decrouy, Martine Cohen-Solal, Marcel Deckert, Amélie E. Coudert, François Brial

published 14 Feb 2025

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Loss of ING4 enhances hematopoietic regeneration in multipotent progenitor cells

Georgina A. Anderson, Marco Hernandez, Carlos Alfaro Quinde, Zanshé Thompson, Vera Binder-Blaser, Alison M. Taylor, Katie L. Kathrein

published 14 Feb 2025

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