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Mouse models

Internal gene segments from a mouse-adapted influenza B virus confer increased pathogenicity to mice

Arne Matthys, Laura Amelinck, Anouk Smet, Tine Ysenbaert, Thorsten U. Vogel, Xavier Saelens, João Paulo Portela Catani

published 23 Mar 2026

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GBP2 promotes podocyte pyroptosis and contributes to the pathogenesis of pediatric lupus nephritis

Yu Sun, Jiahui Wei, Yanjun Zhao, Xingbo Jiang, Chao He, Xianhui Huang, Fengying Lei, Yuanhan Qin

published 19 Mar 2026

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Evaluation of a commercial AI-assisted cell counting software for dopaminergic neurons across species

Ken Kunugitani, Masanori Sawamura, Tomoyuki Taguchi, Tetsuya Hirato, Norihito Uemura, Takashi Ayaki, Etsuro Nakanishi, Hodaka Yamakado, Tomoyuki Ishimoto, Hirotaka Onoe, Tadashi Isa, Riki Matsumoto, Ryosuke Takahashi

published 17 Mar 2026

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Computational modeling-directed combination treatment with etanercept and mifepristone mitigates neuroinflammation in a mouse model of Gulf War Illness

Kimberly A. Kelly, Christopher M. Felton, Brenda K. Billig, Ali A. Yilmaz, James P. O’Callaghan, Travis J. A. Craddock, Gordon Broderick, Nancy Klimas, Lindsay T. Michalovicz

published 17 Mar 2026

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Prenatal cannabis smoke exposure alters placental development in a murine model of pregnancy

Tina Podinic, Maria Sunil, Andie MacAndrew, Cristina Monaco, Grace Lee, Cielle Lockington, Jim Petrik, Amica-Maria Lucas, Thane Tomy, Gregg Tomy, Joanna Kasinska, Laiba Jamshed, Alison C. Holloway, Elyanne M. Ratcliffe, Sandeep Raha

published 16 Mar 2026

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A new mouse mutant with a discrete mutation in Pcdhgc5 reveals that the Protocadherin γC5 isoform is not essential for dendrite arborization in the cerebral cortex

Camille M. Hanes, David M. Steffen, George C. Murray, Robert W. Burgess, Joshua A. Weiner, Andrew M. Garrett

published 12 Mar 2026

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Exendin-4 enhances GLP-1 signaling and reduces anxiety-like behaviors in male heroin withdrawal mice

Yang Xiang, Xiaowei Yan, Rongrong Li, Chunlu Li, Dan Yin, Cancan Luo, Yingqi Xiong, Yan Hong, Yixin Li, Baijuan Xia

published 12 Mar 2026

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An Fc-silent OspA monoclonal antibody passively protects mice from tick and intradermal Borrelia burgdorferi challenge

Daniel Palmer, Atieh Shemshadian, Katherine Berman, Ariana Nobles, Graham G. Willsey, Carol Lyn Piazza, Grace Freeman-Gallant, Michael J. Rudolph, Jeff Bourgeois, Linden Hu, David J. Vance, Nicholas J. Mantis

published 12 Mar 2026

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NFIC suppressed the development of Glioma via modulating the balance of SHP2/PI3K and NF-κB/PTEN Signaling

Hongen Bao, Kai Liu, Naikang Gao, Youle Su, Huiru Bai, Changwu Dou, Fenjun Jiang, Fei Wang

published 11 Mar 2026

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Comparison of neonatal systemic and intracerebroventricular AAV9 gene therapy delivery demonstrating improved behavioral and phenotypic outcomes in a mouse model of Niemann-Pick disease, type C1

Benjamin E. Epstein, Gabrielle M. Soden, Arturo A. Incao, Avani Mylvara, Jonathan Flynn, Fatih Ozsolak, William J. Pavan

published 11 Mar 2026

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Reduced levels of mitochondrial ribosomal protein MRPL54 does not alter Apc related adenoma formation

Claudia N. Spaan, Eileen Daniels, Wouter L. Smit, Ruben J. de Boer, Joana Silva, Jacqueline L. M. Vermeulen, S. Meisner, Vanesa Muncan, Riekelt H. Houtkooper, Jarom Heijmans

published 09 Mar 2026

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Minigenes for heterologous expression of human and mouse cationic trypsinogen

Gergő Berke, Miklós Sahin-Tóth

published 09 Mar 2026

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TLR9/MyD88/NF-κB signaling mediates mental stress-induced exacerbation of psoriasis through immune dysregulation in a mouse model

Qiuhe Song, Dongyang Li, Zhihao Yuan, Chaowen Zhang, Jianqiao Wang, Fangfang Liao, Pengfei Xu, Qipeng Xiao

published 06 Mar 2026

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