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Mouse models

A novel approach to studying infective endocarditis: Ultrasound-guided wire injury and bacterial challenge in mice

Benedikt Bartsch, Ansgar Ackerschott, Muntadher Al Zaidi, Raul Nicolas Jamin, Mariam Louis Fathy Nazir, Moritz Altrogge, Lars Fester, Jessica Lambertz, Mark Coburn, Georg Nickenig, Marijo Parcina, Sebastian Zimmer, Christina Katharina Weisheit

published 07 Apr 2025

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The impact of environmental enrichment on energy metabolism in ovariectomized mice

Chaoran Ju, Ayano Ogura, Yoshikazu Hayashi, Yuko Kawabata, Fulvio D’Acquisto, Tomoyo Kawakubo-Yasukochi, Eijiro Jimi

published 02 Apr 2025

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Targeting NLRP3 and AIM2 signaling pathways by Viscosol alleviates metabolic dysregulations induced inflammatory responses in diabetic neuro- and nephropathy: An in silico and in vivo study

Summan Thahiem, Muhammad Ihsan, Hamza Muneer, Aamir Sohail, Mehmand Khan, Iram Murtaza, Zia Uddin, Muhammad Shafique, Khalid J. Alzahrani, Hamid Ali, Imran Ullah

published 02 Apr 2025

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Voluntarily wheel running protects doxorubicin-induced kidney injury by inhibiting oxidative stress through mitochondrial function

Xin Jiang, Zeyu Wang, Longyun Wang, Yuqi Wang, Lijing Zhao, Hongyu Jiang

published 01 Apr 2025

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Inhibition of PHB1/PHB2 suppresses atherosclerotic plaque formation by interrupting PI3K/AKT/mTOR signaling

Mei Li, Xiaoyan Hu, Xinxin Hu, Fuhua Gao, Ying Cui, Xiaoqing Wei, Yuanhua Qin, Xiaohua An, Ying Zhao, Ying Gao

published 01 Apr 2025

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SMND-309 activates Nrf2 signaling to alleviate acetaminophen-induced hepatotoxicity and oxidative stress

Yao Dong, Ru Jia, Yujie Jiang, Qing Li, Lei Wang, Wensi Ding, Rui Yan, Yujie Qiu, Zhengjie Shi, Wenying Liu, Jing Wang, Sen Xu, Na Li

published 31 Mar 2025

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Detection of central and obstructive sleep apneas in mice: A new surgical and recording protocol

Gabriele Matteoli, Sara Alvente, Chiara Berteotti, Dario Coraci, Viviana Lo Martire, Martina Lops, Elena Miglioranza, Alessandro Silvani, Emilia Volino, Giovanna Zoccoli, Stefano Bastianini

published 28 Mar 2025

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Immunosuppressive drugs and diet interact to modify the gut microbiota and cardiovascular risk factors, and to trigger diabetes

Paul Gabarre, Roberto Palacios, Kevin Perez, Philippe Seksik, Benjamin Bonnard, Christopher Loens, Clara Lefranc, Jean-Paul Pais de Barros, Louis Anjou, Yanis Tamzali, Noël Zahr, Frédéric Jaisser, Jérôme Tourret

published 28 Mar 2025

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Effect of pyrroloquinoline quinone on skin aging in Bmi-1 KO mice and underlying mechanisms

Bin Li, Xiao Meng Yang, Xiong Ming Zhou, Yuan Qing Huang

published 28 Mar 2025

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A simple validation and screening method for CRISPR/Cas9-mediated gene editing in mouse embryos to facilitate genetically modified mice production

Dawid Winiarczyk, Hossein Khodadadi, Paweł Leszczyński, Hiroaki Taniguchi

published 27 Mar 2025

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Bromocriptine improves glucose tolerance in obese mice via central dopamine D2 receptor-independent mechanism

Hiroshi Tsuneki, Takahiro Maeda, Mayumi Takatsuki, Takahiro Sekine, Satsuki Masui, Kengo Onishi, Ryuta Takeda, Masanori Sugiyama, Takeshi Sakurai, Masashi Yanagisawa, Tsutomu Wada, Toshiyasu Sasaoka

published 26 Mar 2025

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Enrichment of Porphyromonas gingivalis in colonic mucosa-associated microbiota and its enhanced adhesion to epithelium in colorectal carcinogenesis: Insights from in vivo and clinical studies

Shunya Motosugi, Naoki Takahashi, Shuhei Mineo, Keisuke Sato, Takahiro Tsuzuno, Yukari Aoki-Nonaka, Nao Nakajima, Kazuya Takahashi, Hiroki Sato, Haruna Miyazawa, Koji Taniguchi, Shuji Terai, Koichi Tabeta

published 25 Mar 2025

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Weighted–VAE: A deep learning approach for multimodal data generation applied to experimental T. cruzi infection

Blanca Vazquez, Nidiyare Hevia-Montiel, Jorge Perez-Gonzalez, Paulina Haro

published 24 Mar 2025

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