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Mouse models

PBRM1 regulates proliferation and the cell cycle in renal cell carcinoma through a chemokine/chemokine receptor interaction pathway

HongKai Wang, YuanYuan Qu, Bo Dai, Yao Zhu, GuoHai Shi, YiPing Zhu, YiJun Shen, HaiLiang Zhang, DingWei Ye

published 28 Aug 2017

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Inhibition of ROCK1 kinase modulates both tumor cells and stromal fibroblasts in pancreatic cancer

Clifford J. Whatcott, Serina Ng, Michael T. Barrett, Galen Hostetter, Daniel D. Von Hoff, Haiyong Han

published 25 Aug 2017

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A Trp53^fl/flPten^fl/fl mouse model of undifferentiated pleomorphic sarcoma mediated by adeno-Cre injection and in vivo bioluminescence imaging

Marisa R. Buchakjian, Nicole M. Merritt, Devon L. Moose, Adam J. Dupuy, Munir R. Tanas, Michael D. Henry

published 25 Aug 2017

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Trehalose improves traumatic brain injury-induced cognitive impairment

Stuart D. Portbury, Dominic J. Hare, David I. Finkelstein, Paul A. Adlard

published 24 Aug 2017

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Effects of subconjunctival administration of anti-high mobility group box 1 on dry eye in a mouse model of Sjӧgren’s syndrome

Kyeong Hwan Kim, Dong Hyun Kim, Hyun Jeong Jeong, Jin Suk Ryu, Yu Jeong Kim, Joo Youn Oh, Mee Kum Kim, Won Ryang Wee

published 24 Aug 2017

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Differences in pathogenicity of three animal isolates of Mycobacterium species in a mouse model

Haodi Dong, Yue Lv, Srinand Sreevatsan, Deming Zhao, Xiangmei Zhou

published 24 Aug 2017

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Mice deficient in the anti-haemophilic coagulation factor VIII show increased von Willebrand factor plasma levels

Klytaimnistra Kiouptsi, Alexandra Grill, Amrit Mann, Mareike Döhrmann, Maren Lillich, Sven Jäckel, Frano Malinarich, Henning Formes, Davit Manukyan, Saravanan Subramaniam, Avinash Khandagale, Cornelia Karwot, Serge C. Thal, Markus Bosmann, Inge Scharrer, Kerstin Jurk, Christoph Reinhardt

published 24 Aug 2017

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Progranulin gene delivery reduces plaque burden and synaptic atrophy in a mouse model of Alzheimer's disease

Jackalina M. Van Kampen, Denis G. Kay

published 24 Aug 2017

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DNA strand breaks and TDP-43 mislocation are absent in the murine hSOD1G93A model of amyotrophic lateral sclerosis in vivo and in vitro

Diane Penndorf, Vedrana Tadić, Otto W. Witte, Julian Grosskreutz, Alexandra Kretz

published 23 Aug 2017

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Restored nitric oxide bioavailability reduces the severity of acute-to-chronic transition in a mouse model of aristolochic acid nephropathy

Inès Jadot, Vanessa Colombaro, Blanche Martin, Isabelle Habsch, Olivia Botton, Joëlle Nortier, Anne-Emilie Declèves, Nathalie Caron

published 23 Aug 2017

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Fructose diet alleviates acetaminophen-induced hepatotoxicity in mice

Sungjoon Cho, Ashutosh Tripathi, George Chlipala, Stefan Green, Hyunwoo Lee, Eugene B. Chang, Hyunyoung Jeong

published 23 Aug 2017

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Time-course global proteome analyses reveal an inverse correlation between Aβ burden and immunoglobulin M levels in the APPNL-F mouse model of Alzheimer disease

Hansen Wang, Declan Williams, Jennifer Griffin, Takashi Saito, Takaomi C. Saido, Paul E. Fraser, Ekaterina Rogaeva, Gerold Schmitt-Ulms

published 23 Aug 2017

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Combinatorial regulation of a Blimp1 (Prdm1) enhancer in the mouse retina

Taylor S. Mills, Tatiana Eliseeva, Stephanie M. Bersie, Grace Randazzo, Jhenya Nahreini, Ko Uoon Park, Joseph A. Brzezinski IV

published 22 Aug 2017

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