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Mouse models

Inflammatory and non-inflammatory monocytes as novel prognostic biomarkers of survival in SOD1G93A mouse model of Amyotrophic Lateral Sclerosis

Samanta Gasco, Pilar Zaragoza, Alberto García-Redondo, Ana C. Calvo, Rosario Osta

published 08 Sep 2017

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Loss of SPRR3 in ApoE^-/- mice leads to atheroma vulnerability through Akt dependent and independent effects in VSMCs

Caressa D. Lietman, Amanda K. Segedy, Bin Li, Sergio Fazio, James B. Atkinson, MacRae F. Linton, Pampee P. Young

published 08 Sep 2017

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Activation of endoplasmic reticulum stress response by enhanced polyamine catabolism is important in the mediation of cisplatin-induced acute kidney injury

Kamyar Zahedi, Sharon Barone, Christina Destefano-Shields, Marybeth Brooks, Tracy Murray-Stewart, Matthew Dunworth, Weimin Li, Joanne R. Doherty, Mark A. Hall, Roger D. Smith, John L. Cleveland, Robert A. Casero Jr., Manoocher Soleimani

published 08 Sep 2017

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Modulation of the endogenous omega-3 fatty acid and oxylipin profile in vivo—A comparison of the fat-1 transgenic mouse with C57BL/6 wildtype mice on an omega-3 fatty acid enriched diet

Annika I. Ostermann, Patrick Waindok, Moritz J. Schmidt, Cheng-Ying Chiu, Christopher Smyl, Nadine Rohwer, Karsten-H. Weylandt, Nils Helge Schebb

published 08 Sep 2017

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Differential regulation of innate immune cytokine production through pharmacological activation of Nuclear Factor-Erythroid-2-Related Factor 2 (NRF2) in burn patient immune cells and monocytes

Timothy K. Eitas, Wesley Stepp, Lucas Sjeklocha, Clayton Long, Caitlin Riley, James Callahan, Yolanda Sanchez, Peter Gough, Laquanda Knowlin, David van Duin, Shiara Ortiz-Pujols, Samuel Jones, Robert Maile, Zhi Hong, Scott Berger, Bruce Cairns

published 08 Sep 2017

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Hepatitis C virus mediated chronic inflammation and tumorigenesis in the humanised immune system and liver mouse model

Zhiqiang Zheng, Ching Wooen Sze, Choong Tat Keng, Muthafar Al-Haddawi, Min Liu, Sue Yee Tan, Hwee Ling Kwek, Zhisheng Her, Xue Ying Chan, Bhaskar Barnwal, Eva Loh, Kenneth Tou En Chang, Thiam Chye Tan, Yee-Joo Tan, Qingfeng Chen

published 08 Sep 2017

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Reduced Slc1a1 expression is associated with neuroinflammation and impaired sensorimotor gating and cognitive performance in mice: Implications for schizophrenia

Parisa Afshari, Wei-Dong Yao, Frank A. Middleton

published 08 Sep 2017

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Downregulation of autophagy is associated with severe ischemia-reperfusion-induced acute kidney injury in overexpressing C-reactive protein mice

Ao Bian, Mingjun Shi, Brianna Flores, Nancy Gillings, Peng Li, Shirley Xiao Yan, Beth Levine, Changying Xing, Ming Chang Hu

published 08 Sep 2017

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ARF6 mediates nephrin tyrosine phosphorylation-induced podocyte cellular dynamics

Jamie S. Lin, Jin Seok Jeon, Qingfeng Fan, Hetty N. Wong, Matthew B. Palmer, Lawrence B. Holzman

published 07 Sep 2017

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The osteogenic cell surface marker BRIL/IFITM5 is dispensable for bone development and homeostasis in mice

Alexa Patoine, Abdallah Husseini, Bahar Kasaai, Marie-Hélène Gaumond, Pierre Moffatt

published 07 Sep 2017

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Prevention of vaginal and rectal HIV transmission by antiretroviral combinations in humanized mice

Philippe A. Gallay, Udayan Chatterji, Aaron Kirchhoff, Angel Gandarilla, Manjula Gunawardana, Richard B. Pyles, Mark A. Marzinke, John A. Moss, Marc M. Baum

published 07 Sep 2017

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Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingi

Silmara R. Sousa, Joshua S. Wingerd, Andreas Brust, Christopher Bladen, Lotten Ragnarsson, Volker Herzig, Jennifer R. Deuis, Sebastien Dutertre, Irina Vetter, Gerald W. Zamponi, Glenn F. King, Paul F. Alewood, Richard J. Lewis

published 07 Sep 2017

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Runx1 mediates the development of the granular convoluted tubules in the submandibular glands

Hitomi Ono Minagi, Safiye Esra Sarper, Hiroshi Kurosaka, Koh-ichi Kuremoto, Ichiro Taniuchi, Takayoshi Sakai, Takashi Yamashiro

published 06 Sep 2017

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