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Mouse models

Interferon-γ treatment in vitro elicits some of the changes in cathepsin S and antigen presentation characteristic of lacrimal glands and corneas from the NOD mouse model of Sjögren’s Syndrome

Zhen Meng, Wannita Klinngam, Maria C. Edman, Sarah F. Hamm-Alvarez

published 13 Sep 2017

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The cytoprotective protein clusterin is overexpressed in hypergastrinemic rodent models of oxyntic preneoplasia and promotes gastric cancer cell survival

Pål Vange, Torunn Bruland, Berit Doseth, Reidar Fossmark, Mirta M. L. Sousa, Vidar Beisvag, Øystein Sørdal, Gunnar Qvigstad, Helge L. Waldum, Arne K. Sandvik, Ingunn Bakke

published 13 Sep 2017

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Testing the effects of sensory stimulation as a collateral-based therapeutic for ischemic stroke in C57BL/6J and CD1 mouse strains

Aneeka M. Hancock, Ron D. Frostig

published 13 Sep 2017

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Carbidopa, a drug in use for management of Parkinson disease inhibits T cell activation and autoimmunity

Huabin Zhu, Henrique Lemos, Brinda Bhatt, Bianca N. Islam, Abhijit Singh, Ashish Gurav, Lei Huang, Darren D. Browning, Andrew Mellor, Sadanand Fulzele, Nagendra Singh

published 12 Sep 2017

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Inflammatory and non-inflammatory monocytes as novel prognostic biomarkers of survival in SOD1G93A mouse model of Amyotrophic Lateral Sclerosis

Samanta Gasco, Pilar Zaragoza, Alberto García-Redondo, Ana C. Calvo, Rosario Osta

published 08 Sep 2017

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Loss of SPRR3 in ApoE^-/- mice leads to atheroma vulnerability through Akt dependent and independent effects in VSMCs

Caressa D. Lietman, Amanda K. Segedy, Bin Li, Sergio Fazio, James B. Atkinson, MacRae F. Linton, Pampee P. Young

published 08 Sep 2017

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Activation of endoplasmic reticulum stress response by enhanced polyamine catabolism is important in the mediation of cisplatin-induced acute kidney injury

Kamyar Zahedi, Sharon Barone, Christina Destefano-Shields, Marybeth Brooks, Tracy Murray-Stewart, Matthew Dunworth, Weimin Li, Joanne R. Doherty, Mark A. Hall, Roger D. Smith, John L. Cleveland, Robert A. Casero Jr., Manoocher Soleimani

published 08 Sep 2017

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Modulation of the endogenous omega-3 fatty acid and oxylipin profile in vivo—A comparison of the fat-1 transgenic mouse with C57BL/6 wildtype mice on an omega-3 fatty acid enriched diet

Annika I. Ostermann, Patrick Waindok, Moritz J. Schmidt, Cheng-Ying Chiu, Christopher Smyl, Nadine Rohwer, Karsten-H. Weylandt, Nils Helge Schebb

published 08 Sep 2017

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Differential regulation of innate immune cytokine production through pharmacological activation of Nuclear Factor-Erythroid-2-Related Factor 2 (NRF2) in burn patient immune cells and monocytes

Timothy K. Eitas, Wesley Stepp, Lucas Sjeklocha, Clayton Long, Caitlin Riley, James Callahan, Yolanda Sanchez, Peter Gough, Laquanda Knowlin, David van Duin, Shiara Ortiz-Pujols, Samuel Jones, Robert Maile, Zhi Hong, Scott Berger, Bruce Cairns

published 08 Sep 2017

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Hepatitis C virus mediated chronic inflammation and tumorigenesis in the humanised immune system and liver mouse model

Zhiqiang Zheng, Ching Wooen Sze, Choong Tat Keng, Muthafar Al-Haddawi, Min Liu, Sue Yee Tan, Hwee Ling Kwek, Zhisheng Her, Xue Ying Chan, Bhaskar Barnwal, Eva Loh, Kenneth Tou En Chang, Thiam Chye Tan, Yee-Joo Tan, Qingfeng Chen

published 08 Sep 2017

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Reduced Slc1a1 expression is associated with neuroinflammation and impaired sensorimotor gating and cognitive performance in mice: Implications for schizophrenia

Parisa Afshari, Wei-Dong Yao, Frank A. Middleton

published 08 Sep 2017

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Downregulation of autophagy is associated with severe ischemia-reperfusion-induced acute kidney injury in overexpressing C-reactive protein mice

Ao Bian, Mingjun Shi, Brianna Flores, Nancy Gillings, Peng Li, Shirley Xiao Yan, Beth Levine, Changying Xing, Ming Chang Hu

published 08 Sep 2017

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ARF6 mediates nephrin tyrosine phosphorylation-induced podocyte cellular dynamics

Jamie S. Lin, Jin Seok Jeon, Qingfeng Fan, Hetty N. Wong, Matthew B. Palmer, Lawrence B. Holzman

published 07 Sep 2017

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