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Mouse models

Adipocyte-specific deletion of Dbc1 does not recapitulate healthy obesity phenotype but suggests regulation of inflammation signaling

Leonardo Santos, Rafael Sebastián Fort, Geraldine Schlapp, Karina Cal, Valentina Perez-Torrado, Maria Noel Meikle, Ana Paula Mulet, Camila Espasandín, Camila Chiesa, José R. Sotelo-Silveira, Jose M. Verdes, Paola Contreras, Aldo J. Calliari, Martina Crispo, Jose L. Badano, Carlos Escande

published 02 May 2025

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Comparison of accumulation and distribution of PEGylated and CD-47-functionalized magnetic nanoporous silica nanoparticles in an in vivo mouse model of implant infection

Heidi Harting, Timo Herrmann, Nina Ehlert, Jessica Meißner, Nina Angrisani, Janin Reifenrath

published 02 May 2025

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CD38-targeted attenuated interferon alpha immunocytokine activates both innate and adaptive immune cells to drive anti-tumor activity

James F. Sampson, Hong Zhang, Dongmei Zhang, Mingying Bi, Adam Hinthorne, Sakeena Syed, Yuhong Zhang, Nibedita Chattopadhyay, Sabrina Collins, Sarah Pogue, Pia Björck, Michael Curley

published 02 May 2025

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Curcumin ameliorates aging-induced blood-testis barrier disruption by regulating AMPK/mTOR mediated autophagy

Chen Xue, Zhenxing Yan, Wenjing Cheng, Dong Zhang, Rong Zhang, Hongwei Duan, Lihong Zhang, Xiaofei Ma, Junjie Hu, Jian Kang, Xiaojun Ma

published 24 Apr 2025

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The impact of Connexin 43 deficiency on the cell shape and cytoskeleton of murine Sertoli cells: A house with ramshackle walls?

Mareike Ueffing, Marion Langeheine, Sarah Gniesmer, Kristina Rode, Sarah Staggenborg, Gudrun Wirth, Kerstin Rohn, Rüdiger Koch, Ines Blume, Christiane Pfarrer, Christoph Wrede, Ralph Brehm

published 24 Apr 2025

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Mitochondria-targeted ROS scavenger JP4-039 improves cardiac function in a post-myocardial infarction animal model and induces angiogenesis in vitro

Rayane Brinck Teixeira, Jane H. Albro, Mohamed Sabra, Taslova Abedin, Aja N. Tucker, Raj Sidharth, Frank W. Sellke, Peter Wipf, M. Ruhul Abid

published 24 Apr 2025

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Enhancement of YTHDF2 plays a protective role in acute IRI models through downregulation of TUG1 expression

Hong-Fei He, Shuang Hou, Xiao-Ya Ma, Song-song Huang, Bo Yang, Jun-Kang Wang, Yuan Xu, Lei Tan, Hai-Yang Li

published 24 Apr 2025

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Multisensory gamma stimulation enhances adult neurogenesis and improves cognitive function in male mice with Down Syndrome

Md Rezaul Islam, Brennan Jackson, Maeesha Tasnim Naomi, Brooke Schatz, Noah Tan, Mitchell Murdock, Dong Shin Park, Daniela Rodrigues Amorim, Xueqiao Jiang, S. Sebastian Pineda, Chinnakkaruppan Adaikkan, Vanesa Fernandez Avalos, Ute Geigenmuller, Rosalind Mott Firenze, Manolis Kellis, Edward S. Boyden, Li-Huei Tsai

published 24 Apr 2025

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Evaluation of intake of aged garlic extract and organosulfur compounds on progressive hearing loss in DBA/2J mice

Hideaki Oike, Kyoko Yamasaki, Kenji Hashiguchi, Honoka Uehira

published 23 Apr 2025

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Photobiomodulation therapy increases neural stem cell pool in aged 3xTg-AD mice

Kevin J. Johnson, Kathia Johnson, Auston Grant, Giulio Taglialatela, Maria-Adelaide Micci

published 22 Apr 2025

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CCR2 dependent recruited pro-inflammatory monocytes contribute to the development of left ventricular hypertrophy in mice upon transverse aortic constriction

Lars Eichhorn, Jan Lukas Kleiner, Benedikt Bartsch, Mariam Louis Fathy Nazir, Yunyang Zhang, Mark Coburn, Stilla Frede, Christina Katharina Weisheit

published 21 Apr 2025

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Efficacy of Quality and Quantity media-cultured mononuclear cells for promoting peripheral nerve regeneration in mouse model

Nutthawut Akaranuchat, Nuttapol Chruewkamlow, Chutipon Sathan-ard, Phakawan Phutthakunphithak, Sompol Tapechum, Chanean Ruangsetakit, Nuttawut Sermsathanasawadi

published 16 Apr 2025

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Host responses to S. pneumoniae in wild type and Mertk mutant mice

Matthew K. McPeek, Jessica R. Martin, John C. Gomez, Yitong Li, Hong Dang, H. Shelton Earp, Claire M. Doerschuk

published 16 Apr 2025

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