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Mouse models

Zinc-finger protein 418 overexpression protects against cardiac hypertrophy and fibrosis

Liming Pan, Mengting Sheng, Zirui Huang, Zhilin Zhu, Chunli Xu, Lin Teng, Ling He, Chen Gu, Cai Yi, Junming Li

published 24 Oct 2017

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Discovery and pharmacological characterization of a new class of prolyl-tRNA synthetase inhibitor for anti-fibrosis therapy

Akira Shibata, Masako Kuno, Ryutaro Adachi, Yosuke Sato, Harumi Hattori, Atsushi Matsuda, Yuumi Okuzono, Keiko Igaki, Yusuke Tominari, Terufumi Takagi, Masato Yabuki, Masanori Okaniwa

published 24 Oct 2017

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Endothelial CaMKII as a regulator of eNOS activity and NO-mediated vasoreactivity

Shubha Murthy, Olha M. Koval, Juan M. Ramiro Diaz, Santosh Kumar, Daniel Nuno, Jason A. Scott, Chantal Allamargot, Linda J. Zhu, Kim Broadhurst, Velarchana Santhana, William J. Kutschke, Kaikobad Irani, Kathryn G. Lamping, Isabella M. Grumbach

published 23 Oct 2017

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Inhibition of miR-142-5P ameliorates disease in mouse models of experimental colitis

Nicolette W. Duijvis, Perry D. Moerland, Cindy Kunne, Monique M. W. Slaman, Faas H. van Dooren, Esther W. Vogels, Wouter J. de Jonge, Sybren L. Meijer, Kees Fluiter, Anje A. te Velde

published 23 Oct 2017

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In vitro modeling of experimental succinic semialdehyde dehydrogenase deficiency (SSADHD) using brain-derived neural stem cells

Kara R. Vogel, Garrett R. Ainslie, Erwin E. Jansen, Gajja S. Salomons, Jean-Baptiste Roullet, K. Michael Gibson

published 20 Oct 2017

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Treatment with the NR4A1 agonist cytosporone B controls influenza virus infection and improves pulmonary function in infected mice

Benoit Egarnes, Marie-Renée Blanchet, Jean Gosselin

published 20 Oct 2017

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XRCC5 cooperates with p300 to promote cyclooxygenase-2 expression and tumor growth in colon cancers

Zhifeng Zhang, Fufu Zheng, Zhenlong Yu, Jiajiao Hao, Miao Chen, Wendan Yu, Wei Guo, Yiming Chen, Wenlin Huang, Zhijun Duan, Wuguo Deng

published 19 Oct 2017

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An inducible mouse model of podocin-mutation-related nephrotic syndrome

Mansoureh Tabatabaeifar, Tanja Wlodkowski, Ivana Simic, Helga Denc, Geraldine Mollet, Stefanie Weber, John Julius Moyers, Barbara Brühl, Michael Joseph Randles, Rachel Lennon, Corinne Antignac, Franz Schaefer

published 19 Oct 2017

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Functional connectivity structure of cortical calcium dynamics in anesthetized and awake mice

Patrick W. Wright, Lindsey M. Brier, Adam Q. Bauer, Grant A. Baxter, Andrew W. Kraft, Matthew D. Reisman, Annie R. Bice, Abraham Z. Snyder, Jin-Moo Lee, Joseph P. Culver

published 19 Oct 2017

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Association between RNA-binding protein Ptbp2 and germ cell injury in an experimentally-induced unilateral cryptorchidism murine model

Xianming Dou, Jingjing Gao, Pan Gao, Dongdong Tang, Dangwei Peng, Jun Mao, Zhenyu Huang, Peng Chen, He Chen, Shengwei Ke, Chaozhao Liang, Xiansheng Zhang

published 18 Oct 2017

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Tubastatin ameliorates pulmonary fibrosis by targeting the TGFβ-PI3K-Akt pathway

Shigeki Saito, Yan Zhuang, Bin Shan, Svitlana Danchuk, Fayong Luo, Martina Korfei, Andreas Guenther, Joseph A. Lasky

published 18 Oct 2017

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Dietary vitamin D3 deficiency exacerbates sinonasal inflammation and alters local 25(OH)D₃ metabolism

Jennifer K. Mulligan, Whitney N. Pasquini, William W. Carroll, Tucker Williamson, Nicholas Reaves, Kunal J. Patel, Elliott Mappus, Rodney J. Schlosser, Carl Atkinson

published 18 Oct 2017

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Conjugated nanoliposome with the HER2/neu-derived peptide GP2 as an effective vaccine against breast cancer in mice xenograft model

Atefeh Razazan, Javad Behravan, Atefeh Arab, Nastaran Barati, Leila Arabi, Zahra Gholizadeh, Mahdi Hatamipour, Amin Reza Nikpoor, Amir Abbas Momtazi-Borojeni, Fatemeh Mosaffa, Mohamad Hosein Ghahremani, Mahmoud Reza Jaafari

published 18 Oct 2017

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