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Mouse models

Notch signaling and progenitor/ductular reaction in steatohepatitis

Carola M. Morell, Romina Fiorotto, Marica Meroni, Aileen Raizner, Barbara Torsello, Massimiliano Cadamuro, Gaia Spagnuolo, Eleanna Kaffe, Salvatore Sutti, Emanuele Albano, Mario Strazzabosco

published 15 Nov 2017

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Expression of Toll-like receptors (TLRs) in the lungs of an experimental sepsis mouse model

Anargyros Bakopoulos, Alkistis Kapelouzou, Diamantis I. Tsilimigras, Michalis Katsimpoulas, Dimitrios Schizas, Chrysostomos Aravanis, Evaggelos Balafas, Manolis Mavroidis, Kitty Pavlakis, Anastasios Machairas, Theodore Liakakos

published 14 Nov 2017

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STING expression and response to treatment with STING ligands in premalignant and malignant disease

Jason R. Baird, Zipeng Feng, Hong D. Xiao, David Friedman, Ben Cottam, Bernard A. Fox, Gwen Kramer, Rom S. Leidner, R. Bryan Bell, Kristina H. Young, Marka R. Crittenden, Michael J. Gough

published 14 Nov 2017

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Long-term retinal cone rescue using a capsid mutant AAV8 vector in a mouse model of CNGA3-achromatopsia

Xufeng Dai, Ying He, Hua Zhang, Yangyang Zhang, Yan Liu, Muran Wang, Hao Chen, Ji-jing Pang

published 13 Nov 2017

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Delivery of epirubicin via slow infusion as a strategy to mitigate chemotherapy-induced cardiotoxicity

Fang Yang, Qiao Lei, Lu Li, Jian Chang He, Jiajia Zeng, Chunxiang Luo, Sai-Ching Jim Yeung, Runxiang Yang

published 13 Nov 2017

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Improved segmented modified Look-Locker inversion recovery T₁ mapping sequence in mice

Maryam Nezafat, Isabel T. Ramos, Markus Henningsson, Andrea Protti, Tamer Basha, René M. Botnar

published 09 Nov 2017

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The Mouse Model of Pancreatic Cancer Atlas (MMPCA) for classification of pancreatic cancer lesions: A large histological investigation of the Ptf1a^Cre/+;LSL-Kras^G12D/+ transgenic mouse model of pancreatic cancer

Michelle J. Veite-Schmahl, Adam C. Rivers, Daniel P. Regan, Michael A. Kennedy

published 09 Nov 2017

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Effects of CD49d-targeted antisense-oligonucleotide on α4 integrin expression and function of acute lymphoblastic leukemia cells: Results of in vitro and in vivo studies

Yann Duchartre, Stefanie Bachl, Hye Na Kim, Eun Ji Gang, Solah Lee, Hsiao-chuan Liu, Kirk Shung, Ruth Xu, Aaron Kruse, George Tachas, Halvard Bonig, Yong-Mi Kim

published 08 Nov 2017

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Genomic sequencing identifies a few mutations driving the independent origin of primary liver tumors in a chronic hepatitis murine model

Zuyu Yang, Mingming Jia, Guojing Liu, Huaining Hao, Li Chen, Guanghao Li, Sixue Liu, Yawei Li, Chung-I Wu, Xuemei Lu, Shengdian Wang

published 08 Nov 2017

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IFNGR1 signaling is associated with adverse pregnancy outcomes during infection with malaria parasites

Mamoru Niikura, Shin–Ichi Inoue, Shoichiro Mineo, Hiroko Asahi, Fumie Kobayashi

published 08 Nov 2017

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Targeting of cadherin-11 decreases skin fibrosis in the tight skin-1 mouse model

Mesias Pedroza, Robert L. Welschhans, Sandeep K. Agarwal

published 07 Nov 2017

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Febuxostat ameliorates secondary progressive experimental autoimmune encephalomyelitis by restoring mitochondrial energy production in a GOT2-dependent manner

Josephe A. Honorat, Yuji Nakatsuji, Mikito Shimizu, Makoto Kinoshita, Hisae Sumi-Akamaru, Tsutomu Sasaki, Kazushiro Takata, Toru Koda, Akiko Namba, Kazuya Yamashita, Eri Sanda, Manabu Sakaguchi, Atsushi Kumanogoh, Takashi Shirakura, Mizuho Tamura, Saburo Sakoda, Hideki Mochizuki, Tatsusada Okuno

published 06 Nov 2017

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Assessing Zika virus replication and the development of Zika-specific antibodies after a mid-gestation viral challenge in guinea pigs

Craig J. Bierle, Claudia Fernández-Alarcón, Nelmary Hernandez-Alvarado, Jason C. Zabeli, Bradley C. Janus, Dira S. Putri, Mark R. Schleiss

published 03 Nov 2017

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