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Mouse models

Transgenic mice overexpressing Pitx2 in the atria develop tachycardia-bradycardia syndrome

Shunsuke Baba, Satoko Shinjo, Daiki Seya, Hiroki Bochimoto, Toru Akaike, Atsushi Nakano, Susumu Minamisawa

published 04 Sep 2025

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Identification of immune-related biomarkers associated with allergic rhinitis and development of a sample diagnostic model

MaoMeng Wang, Shuang Wang, XinHua Lin, XiaoJing Lv, XueXia Liu, Hua Zhang

published 03 Sep 2025

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A cytotoxic peptide-drug conjugate for tumor-specific delivery of co-injected molecules

Norio Miyamura, Chisato M. Yamazaki, Yasuaki Anami, Kyoji Tsuchikama, Kazuki N. Sugahara

published 02 Sep 2025

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Anti-aging effect of low molecular weight recombinant humanized collagen on photo-aging by activating adherence junction signaling pathways

Kan Tao, Huilin Zhu, Jing Wei

published 29 Aug 2025

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TGFBR1 gene silencing attenuates cardiomyopathy in the HFpEF mouse model

Xuanyang Shen, Weidong Li, Xiaolu Jiang, Hongfu Wen, Yuan Shen, Wen Zhang, Yongjian Peng, Guoping Kang

published 29 Aug 2025

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β-aminopropionitrile-induced thoracic aortopathy is refractory to cilostazol and sildenafil in mice

Samuel C. Tyagi, Sohei Ito, Jacob C. Hubbuch, Michael K. Franklin, Deborah A. Howatt, Hong S. Lu, Alan Daugherty, Hisashi Sawada

published 29 Aug 2025

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Hidden Markov models reveal behavioral state dynamics in depth-related locomotion in mice

Hironobu Shuto, Toshiki Maeda, Chieko Koike, Masayo Takahashi, Michiko Mandai, Take Matsuyama

published 26 Aug 2025

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MSC and HUVEC co-cultured fillers overcome intractable fistula in a new mouse model

Soichiro Hirasawa, Kentaro Murakami, Masayuki Kano, Satoshi Endo, Takeshi Toyozumi, Yasunori Matsumoto, Ryota Otsuka, Nobufumi Sekino, Tadashi Shiraishi, Takahiro Ryuzaki, Kazuya Kinoshita, Takuma Sasaki, Hisahiro Matsubara

published 21 Aug 2025

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Preliminary analysis of the metabolic and physical activity profiles of mice lacking the slc43a3-encoded equilibrative nucleobase transporter 1

Aaron L. Sayler, James R. Hammond

published 21 Aug 2025

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Detection of Fusarium solani using cutinase antibody and its application in diagnosing fungal keratitis in an animal model

Hye-Jeong Jo, Min-Jeong Kim, Hae-Ahm Lee, Fu-Shi Quan, Hyun-Hee Kong, Eun-Kyung Moon

published 20 Aug 2025

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The relationship between obstructive sleep apnea and atrial remodeling, fibrosis and inflammation

Dasheng Lu, Kai Wang

published 20 Aug 2025

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Ribitol treatment rescues dystroglycanopathy mice with common L276I mutation

Bo Wu, Pei Juan Lu, Morgan Drains, Sapana Shah, Anthony Blaeser, Victoria Leroy, Jessalyn Killilee, Molly Holbrook, Qi Long Lu

published 20 Aug 2025

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Cysteine dioxygenase knockout and taurine deficiency impair mouse uterine adenogenesis by inhibiting epithelial cell proliferation and enhancing apoptosis

Hui Liu, Yuneng Gong, Xiaoyan Qu, Sheng Cui, Di Zhang

published 18 Aug 2025

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