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Mouse models

Role of IL-23 signaling in the progression of premalignant oral lesions to cancer

Blaine Caughron, Yi Yang, M. Rita I. Young

Design and preclinical characterization of ALXN1210: A novel anti-C5 antibody with extended duration of action

Douglas Sheridan, Zhao-Xue Yu, [ ... ], Paul Tamburini

Deletion of pro-angiogenic factor vasohibin-2 ameliorates glomerular alterations in a mouse diabetic nephropathy model

Kana Masuda, Katsuyuki Tanabe, [ ... ], Jun Wada

DEC205-DC targeted DNA vaccine against CX3CR1 protects against atherogenesis in mice

Jimmy Jianheng Zhou, Yuan Min Wang, [ ... ], Anne M. Durkan

The flavonoid compound apigenin prevents colonic inflammation and motor dysfunctions associated with high fat diet-induced obesity

Daniela Gentile, Matteo Fornai, [ ... ], Luca Antonioli

XJB-5-131-mediated improvement in physiology and behaviour of the R6/2 mouse model of Huntington's disease is age- and sex- dependent

Aris A. Polyzos, Nigel I. Wood, [ ... ], Cynthia T. McMurray

Early intervention of tau pathology prevents behavioral changes in the rTg4510 mouse model of tauopathy

Xiaohai Wang, Karen Smith, [ ... ], Jason M. Uslaner

Toll-like receptor 3 (TLR3) promotes the resolution of Chlamydia muridarum genital tract infection in congenic C57BL/6N mice

Sebastian E. Carrasco, Sishun Hu, [ ... ], Wilbert A. Derbigny

Hypocomplementemia is associated with worse renal survival in ANCA-positive granulomatosis with polyangiitis and microscopic polyangiitis

Samuel Deshayes, Achille Aouba, [ ... ], Nicolas Martin Silva

Sildenafil ameliorates right ventricular early molecular derangement during left ventricular pressure overload

Yousuke Imai, Taro Kariya, [ ... ], Eiki Takimoto

Inositol 1,4,5-trisphosphate 3-kinase A overexpressed in mouse forebrain modulates synaptic transmission and mGluR-LTD of CA1 pyramidal neurons

Byungil Choi, Hyun Woo Lee, [ ... ], Hyun Kim

Sequestration of synaptic proteins by alpha-synuclein aggregates leading to neurotoxicity is inhibited by small peptide

Mal-Gi Choi, Mi Jin Kim, [ ... ], Won-Jong Oh

Novel monoclonal antibodies targeting the microtubule-binding domain of human tau

Cara L. Croft, Brenda D. Moore, [ ... ], Benoit I. Giasson

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