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Mouse models

ARQ-197, a small-molecule inhibitor of c-Met, reduces tumour burden and prevents myeloma-induced bone disease in vivo

Darren L. Lath, Clive H. Buckle, Holly R. Evans, Matthew Fisher, Jenny M. Down, Michelle A. Lawson, Andrew D. Chantry

published 20 Jun 2018

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TWEAK increases CD74 expression and sensitizes to DDT proinflammatory actions in tubular cells

Lara Valiño-Rivas, Leticia Cuarental, Osvaldo Grana, Richard Bucala, Lin Leng, Ana Sanz, Gonzalo Gomez, Alberto Ortiz, Maria Dolores Sanchez-Niño

published 20 Jun 2018

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Nephrin is necessary for podocyte recovery following injury in an adult mature glomerulus

Rakesh Verma, Madhusudan Venkatareddy, Anne Kalinowski, Theodore Li, Joanna Kukla, Ashomathi Mollin, Gabriel Cara-Fuentes, Sanjeevkumar R. Patel, Puneet Garg

published 20 Jun 2018

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Sociability and synapse subtype-specific defects in mice lacking SRPX2, a language-associated gene

Breeanne M. Soteros, Qifei Cong, Christian R. Palmer, Gek-Ming Sia

published 19 Jun 2018

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Peptide-conjugated phosphodiamidate oligomer-mediated exon skipping has benefits for cardiac function in mdx and Cmah-/-mdx mouse models of Duchenne muscular dystrophy

Alison M. Blain, Elizabeth Greally, Graham McClorey, Raquel Manzano, Corinne A. Betts, Caroline Godfrey, Liz O’Donovan, Thibault Coursindel, Mike J. Gait, Matthew J. Wood, Guy A. MacGowan, Volker W. Straub

published 18 Jun 2018

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Lat^Y136F knock-in mouse model for human IgG4-related disease

Kazunori Yamada, Masahiko Zuka, Kiyoaki Ito, Keishi Mizuguchi, Yasushi Kakuchi, Tamehito Onoe, Yasunori Suzuki, Masakazu Yamagishi, Shozo Izui, Marie Malissen, Bernard Malissen, Mitsuhiro Kawano

published 14 Jun 2018

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Ilheus and Saint Louis encephalitis viruses elicit cross-protection against a lethal Rocio virus challenge in mice

Alberto Anastacio Amarilla, Marcilio Jorge Fumagalli, Mario Luis Figueiredo, Djalma S. Lima-Junior, Nilton Nascimento Santos-Junior, Helda Liz Alfonso, Veronica Lippi, Amanda Cristina Trabuco, Flavio Lauretti, Vanessa Danielle Muller, David F. Colón, João P. M. Luiz, Andreas Suhrbier, Yin Xiang Setoh, Alexander A. Khromykh, Luiz Tadeu Moraes Figueiredo, Victor Hugo Aquino

published 13 Jun 2018

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Accounting for tumor heterogeneity when using CRISPR-Cas9 for cancer progression and drug sensitivity studies

Jessica F. Olive, Yuanbo Qin, Molly J. DeCristo, Tyler Laszewski, Frances Greathouse, Sandra S. McAllister

published 13 Jun 2018

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Loss of Fnip1 alters kidney developmental transcriptional program and synergizes with TSC1 loss to promote mTORC1 activation and renal cyst formation

Ryan Centini, Mark Tsang, Terri Iwata, Heon Park, Jeffrey Delrow, Daciana Margineantu, Brandon M. Iritani, Haiwei Gu, H. Denny Liggitt, Janella Kang, Lim Kang, David M. Hockenbery, Daniel Raftery, Brian M. Iritani

published 13 Jun 2018

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Tolerogenic β2-glycoprotein I DNA vaccine and FK506 as an adjuvant attenuates experimental obstetric antiphospholipid syndrome

Ya-Hsuan Chao, Der-Yuan Chen, Joung-Liang Lan, Kuo-Tung Tang, Chi-Chien Lin

published 12 Jun 2018

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Therapeutic potential of CPI-613 for targeting tumorous mitochondrial energy metabolism and inhibiting autophagy in clear cell sarcoma

Yuki Egawa, Chiemi Saigo, Yusuke Kito, Toshiaki Moriki, Tamotsu Takeuchi

published 07 Jun 2018

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Candidate gene biodosimetry markers of exposure to external ionizing radiation in human blood: A systematic review

Jerome Lacombe, Chao Sima, Sally A. Amundson, Frederic Zenhausern

published 07 Jun 2018

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Intraperitoneal infusion of mesenchymal stem cell attenuates severity of collagen antibody induced arthritis

Yoojun Nam, Seung Min Jung, Yeri Alice Rim, Hyerin Jung, Kijun Lee, Narae Park, Juryun Kim, Yeonsue Jang, Yong-Beom Park, Sung-Hwan Park, Ji Hyeon Ju

published 07 Jun 2018

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