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Mouse models

Augmenting the antinociceptive effects of nicotinic acetylcholine receptor activity through lynx1 modulation

Neel I. Nissen, Kristin R. Anderson, Huaixing Wang, Hui Sun Lee, Carly Garrison, Samantha A. Eichelberger, Kasarah Ackerman, Wonpil Im, Julie M. Miwa

published 03 Jul 2018

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Development of a novel immunoproteasome digestion assay for synthetic long peptide vaccine design

Hiroshi Wada, Atsushi Shimizu, Toshihiro Osada, Yuki Tanaka, Satoshi Fukaya, Eiji Sasaki

published 03 Jul 2018

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Nitric oxide alters hyaluronan deposition by airway smooth muscle cells

Alana K. Majors, Ritu Chakravarti, Lisa M. Ruple, Rachel Leahy, Dennis J. Stuehr, Mark Lauer, Serpil C. Erzurum, Allison Janocha, Mark A. Aronica

published 02 Jul 2018

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Long-term metabolic effects of malnutrition: Liver steatosis and insulin resistance following early-life protein restriction

Prasad S. Dalvi, Steven Yang, Nathan Swain, Junsoo Kim, Senjuti Saha, Celine Bourdon, Ling Zhang, Rose Chami, Robert H. J. Bandsma

published 02 Jul 2018

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Uncovering the fine print of the CreER^T2-LoxP system while generating a conditional knockout mouse model of Ssrp1 gene

Poorva Sandlesh, Thierry Juang, Alfiya Safina, Michael J. Higgins, Katerina V. Gurova

published 28 Jun 2018

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IDH1-mutated transgenic zebrafish lines: An in-vivo model for drug screening and functional analysis

Ya Gao, Maurice de Wit, Eduard A. Struys, Herma C. Z. van der Linde, Gajja S. Salomons, Martine L. M. Lamfers, Rob Willemsen, Peter A. E. Sillevis Smitt, Pim J. French

published 28 Jun 2018

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Repurposing ebselen for decolonization of vancomycin-resistant enterococci (VRE)

Ahmed AbdelKhalek, Nader S. Abutaleb, Haroon Mohammad, Mohamed N. Seleem

published 28 Jun 2018

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Loxl2 is dispensable for dermal development, homeostasis and tumour stroma formation

Katharina Isabelle Kober, Amparo Cano, Cyrill Géraud, Kalle Sipilä, Seyedeh Atefeh Mobasseri, Christina Philippeos, Angela Oliveira Pisco, Andrew Stannard, Alberto Martin, Fernando Salvador, Vanesa Santos, Michael Boutros, Emanuel Rognoni, Fiona M. Watt

published 28 Jun 2018

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Supervised learning reveals circulating biomarker levels diagnostic of hepatocellular carcinoma in a clinically relevant model of non-alcoholic steatohepatitis; An OAD to NASH

Anne Hwang, Christopher Shi, Edward Zhu, Farha Naaz, Ping Zhou, Zainab Rasheed, Michelle Liu, Lindsey S. Jung, Bin Duan, Jingsong Li, Kai Jiang, Latha Paka, Satishkumar V. Gadhiya, Dibyendu Dana, Quaisar Ali, Michael A. Yamin, Itzhak D. Goldberg, Prakash Narayan

published 26 Jun 2018

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Corticosteroid inhibits differentiation of palmar fibromatosis-derived stem cells (FSCs) through downregulation of transforming growth factor-β1 (TGF-β1)

Jung-Pan Wang, Hsiang-Hsuan Michael Yu, En-Rung Chiang, Jir-You Wang, Po- Hsin Chou, Shih-Chieh Hung

published 26 Jun 2018

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Tcf4 regulates dendritic spine density and morphology in the adult brain

Sophie Crux, Jochen Herms, Mario M. Dorostkar

published 22 Jun 2018

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The route of administration influences the therapeutic index of an anti-proNGF neutralizing mAb for experimental treatment of Diabetic Retinopathy

Pablo F. Barcelona, Alba Galan, Hinyu Nedev, Yifan Jian, Marinko V. Sarunic, H. Uri Saragovi

published 21 Jun 2018

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A G542X cystic fibrosis mouse model for examining nonsense mutation directed therapies

Daniel R. McHugh, Miarasa S. Steele, Dana M. Valerio, Alexander Miron, Rachel J. Mann, David F. LePage, Ronald A. Conlon, Calvin U. Cotton, Mitchell L. Drumm, Craig A. Hodges

published 20 Jun 2018

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