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Mouse models

Role of the Streptococcus suis serotype 2 capsular polysaccharide in the interactions with dendritic cells is strain-dependent but remains critical for virulence

Jean-Philippe Auger, Dominic Dolbec, David Roy, Mariela Segura, Marcelo Gottschalk

published 12 Jul 2018

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SAP97 regulates behavior and expression of schizophrenia risk enriched gene sets in mouse hippocampus

Preetika Gupta, Ogul E. Uner, Soumyashant Nayak, Gregory R. Grant, Robert G. Kalb

published 11 Jul 2018

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Flavonoid compound icariin enhances BMP-2 induced differentiation and signalling by targeting to connective tissue growth factor (CTGF) in SAMP6 osteoblasts

Bing Xu, Xueqiang Wang, Chengliang Wu, Lihe Zhu, Ou Chen, Xiaofeng Wang

published 10 Jul 2018

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An amyloidogenic hexapeptide derived from amylin attenuates inflammation and acute lung injury in murine sepsis

Sidharth Mahapatra, Lihua Ying, Peggy Pui-Kay Ho, Michael Kurnellas, Jonathan Rothbard, Lawrence Steinman, David N. Cornfield

published 10 Jul 2018

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Salivary creatinine and urea are higher in an experimental model of acute but not chronic renal disease

Alexandra Kovalčíková, Katarína Janšáková, Marianna Gyurászová, Ľudmila Podracká, Katarína Šebeková, Peter Celec, Ľubomíra Tóthová

published 06 Jul 2018

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BACE1-cleavage of Sez6 and Sez6L is elevated in Niemann-Pick type C disease mouse brains

Mirsada Causevic, Kristina Dominko, Martina Malnar, Lea Vidatic, Stjepko Cermak, Martina Pigoni, Peer-Hendrik Kuhn, Alessio Colombo, Daniel Havas, Stefanie Flunkert, Jessica McDonald, Jenny M. Gunnersen, Birgit Hutter-Paier, Sabina Tahirovic, Manfred Windisch, Dimitri Krainc, Stefan F. Lichtenthaler, Silva Hecimovic

published 06 Jul 2018

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Linagliptin unmasks specific antioxidant pathways protective against albuminuria and kidney hypertrophy in a mouse model of diabetes

Netanya Y. Spencer, Zhihong Yang, Jensyn Cone Sullivan, Thomas Klein, Robert C. Stanton

published 06 Jul 2018

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Tonsil-derived mesenchymal stem cell-embedded in situ crosslinkable gelatin hydrogel therapy recovers postmenopausal osteoporosis through bone regeneration

Gyungah Kim, Yoon Shin Park, Yunki Lee, Yoon Mi Jin, Da Hyeon Choi, Kyung-Ha Ryu, Yoon Jeong Park, Ki Dong Park, Inho Jo

published 05 Jul 2018

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Inhibition of NF-κB signaling in IKKβF/F;LysM Cre mice causes motor deficits but does not alter pathogenesis of Spinocerebellar ataxia type 1

Austin Ferro, Wenhui Qu, Abigail Lukowicz, Daniel Svedberg, Andrea Johnson, Marija Cvetanovic

published 05 Jul 2018

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Detection of PrP^res in peripheral tissue in pigs with clinical disease induced by intracerebral challenge with sheep-passaged bovine spongiform encephalopathy agent

Carlos Hedman, Alicia Otero, Jean-Yves Douet, Caroline Lacroux, Séverine Lugan, Hicham Filali, Fabien Corbière, Naima Aron, Juan José Badiola, Olivier Andréoletti, Rosa Bolea

published 05 Jul 2018

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Quercetin prevents rhinovirus-induced progression of lung disease in mice with COPD phenotype

Mohammad Farazuddin, Rahul Mishra, Yaxun Jing, Vikram Srivastava, Adam T. Comstock, Umadevi S. Sajjan

published 05 Jul 2018

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The duration of hypothermia affects short-term neuroprotection in a mouse model of neonatal hypoxic ischaemic injury

Eridan Rocha-Ferreira, Amy Vincent, Sarah Bright, Donald M. Peebles, Mariya Hristova

published 03 Jul 2018

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Retinal degeneration mutation in Sftpa1^tm1Kor/J and Sftpd ^-/- targeted mice

Faizah Bhatti, Johannes W. Kung, Frederico Vieira

published 03 Jul 2018

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