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Mouse models

The E3 ubiquitin ligase MARCH1 regulates glucose-tolerance and lipid storage in a sex-specific manner

Candida Bhagwandin, Erin L. Ashbeck, Michael Whalen, Joanna Bandola-Simon, Paul A. Roche, Adam Szajman, Sarah Mai Truong, Betsy C. Wertheim, Yann C. Klimentidis, Satoshi Ishido, Benjamin J. Renquist, Lonnie Lybarger

published 24 Oct 2018

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Imaging breast cancer using a dual-ligand nanochain particle

Gil Covarrubias, Anthony Cha, Abdelrahman Rahmy, Morgan Lorkowski, Vindya Perera, Bernadette O. Erokwu, Chris Flask, Pubudu M. Peiris, William P. Schiemann, Efstathios Karathanasis

published 18 Oct 2018

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Genetics and sex influence peripheral and central innate immune responses and blood-brain barrier integrity

Michelle A. Erickson, W. Sandy Liang, Elizabeth G. Fernandez, Kristin M. Bullock, Jarl A. Thysell, William A. Banks

published 16 Oct 2018

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Maternal fenvalerate exposure during pregnancy impairs growth and neurobehavioral development in mouse offspring

Ji-Jie Liu, Ce Guo, Bo Wang, Meng-Xing Shi, Yang Yang, Zhen Yu, Xiu-Hong Meng, De-Xiang Xu

published 15 Oct 2018

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Cardiac leptin overexpression in the context of acute MI and reperfusion potentiates myocardial remodeling and left ventricular dysfunction

David Kain, Amos J. Simon, Avraham Greenberg, Danny Ben Zvi, Boris Gilburd, Jacob Schneiderman

published 12 Oct 2018

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Thy1 transgenic mice expressing the red fluorescent calcium indicator jRGECO1a for neuronal population imaging in vivo

Hod Dana, Ondrej Novak, Michael Guardado-Montesino, James W. Fransen, Amy Hu, Bart G. Borghuis, Caiying Guo, Douglas S. Kim, Karel Svoboda

published 11 Oct 2018

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Oral carbon monoxide therapy in murine sickle cell disease: Beneficial effects on vaso-occlusion, inflammation and anemia

John D. Belcher, Edward Gomperts, Julia Nguyen, Chunsheng Chen, Fuad Abdulla, Zachary M. Kiser, David Gallo, Howard Levy, Leo E. Otterbein, Gregory M. Vercellotti

published 11 Oct 2018

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Distinct virulence ranges for infection of mice by Bordetella pertussis revealed by engineering of the sensor-kinase BvgS

Elodie Lesne, Loic Coutte, Luis Solans, Stephanie Slupek, Anne-Sophie Debrie, Véronique Dhennin, Philippe Froguel, David Hot, Camille Locht, Rudy Antoine, Françoise Jacob-Dubuisson

published 11 Oct 2018

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The BH3 only Bcl-2 family member BNIP3 regulates cellular proliferation

Amandeep Singh, Meghan Azad, Miriam D. Shymko, Elizabeth S. Henson, Sachin Katyal, David D. Eisenstat, Spencer B. Gibson

published 11 Oct 2018

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Therapeutic potential of tranilast for the treatment of chronic graft-versus-host disease in mice

Shin Mukai, Yoko Ogawa, Hideyuki Saya, Yutaka Kawakami, Kazuo Tsubota

published 11 Oct 2018

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Oral iron exacerbates colitis and influences the intestinal microbiome

Awad Mahalhal, Jonathan M. Williams, Sophie Johnson, Nicholas Ellaby, Carrie A. Duckworth, Michael D. Burkitt, Xuan Liu, Georgina L. Hold, Barry J. Campbell, D. Mark Pritchard, Chris S. Probert

published 11 Oct 2018

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Muscle regeneration is disrupted by cancer cachexia without loss of muscle stem cell potential

Shoya Inaba, Atsushi Hinohara, Masashi Tachibana, Kazutake Tsujikawa, So-ichiro Fukada

published 09 Oct 2018

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Protection induced by a Francisella tularensis subunit vaccine delivered by glucan particles

Adam O. Whelan, Helen C. Flick-Smith, Jane Homan, Zu T. Shen, Zoe Carpenter, Payam Khoshkenar, Ambily Abraham, Nicola J. Walker, Stuart M. Levitz, Gary R. Ostroff, Petra C. F. Oyston

published 08 Oct 2018

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