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Mouse models

Presymptomatic microRNA-based biomarker signatures for the prognosis of localized radiation injury in mice

Lucie Ancel, Jules Gueguen, Guillaume Thoër, Jules Marçais, Aïda Chemloul, Bernard Le Guen, Marc Benderitter, Radia Tamarat, Maâmar Souidi, Mohamed Amine Benadjaoud, Stéphane Flamant

published 08 Aug 2025

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Homocysteine induces ferroptosis in cardiomyocytes by disrupting β-catenin/GPX4 pathway

Yanping Lei, Rui Liu, Lewu Xu, Yue Zhao

published 06 Aug 2025

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Hyperuricemia in ob/ob mice relates to hepatocellular pyruvate metabolism/ xanthine oxidase axis

Shan Zhang, Shasha Hu, Haibo Tan, Ertao Jia

published 06 Aug 2025

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Role of G-protein-coupled receptor kinase 4 on the dysfunction of renal Mas receptor in hypertension

Lin Chen, Jiayao Chen, Jindong Wan, Muqing Shao, Caiyu Chen, Shuo Zheng, Fuwei Zhang, Jian Yang

published 05 Aug 2025

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Partial FAM19A5 deficiency in mice leads to disrupted spine maturation, hyperactivity, and an altered fear response

Anu Shahapal, Sumi Park, Sangjin Yoo, Shi-Xun Ma, Jongha Lee, Hoyun Kwak, Jong-Ik Hwang, Jae Young Seong

published 05 Aug 2025

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Loss of Ufsp1 does not cause major changes at the neuromuscular junction

Cristofer Calvo, Coalesco Smith, Taejeong Song, Fabian Montecino-Morales, Sakthivel Sadayappan, Douglas P. Millay, Minchul Kim

published 01 Aug 2025

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Identification of differentially expressed genes associated with ferroptosis in ulcerative colitis

Fang Zhang, Xin Jiang, Xuyu Chen, Zheng Wang, Jianlei Xia, Bingcheng Wang, Mei Wang, Yanbing Ding

published 29 Jul 2025

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Recombinant human alpha-N-acetylglucosamine-6-sulfatase delivered to Sanfilippo D mice with repeated intracerebroventricular injections corrects CNS pathology

Grant L. Austin, Feng Wang, Steven Q. Le, Alexander Sorensen, Shan Li, Lai C. Foong, Srikanth Singamsetty, Jill Wood, Tsui-Fen Chou, Patricia I. Dickson

published 25 Jul 2025

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Lard intake results in better hypothalamic leptin responsiveness than beef tallow intake during overnutrition

Mutsumi Ikeda, Tamae Shiino, Kai Naruke, Nozomi Takahashi, Hanako Kanzaki, Ran Xu, Toshimi Shirozu, Misato Nakano, Miharu Murae, Yui Funatsu, Kentaro Kaneko

published 21 Jul 2025

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Cellular repressor of E1A-stimulated genes 1 enhances skeletal muscle performance through the stimulation of muscle differentiation and Akt-mTOR signaling pathway activation

Ayumi Goto, Michihiro Hashimoto, Sho Yokogawa, Yuzu Naruse, Hitoshi Yamashita

published 17 Jul 2025

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Peripheral administration of blood from tau transgenic animals exacerbates brain tau-associated pathology

Laura Vegas-Gomez, Matias Pizarro, Jesus Garcia-Martin, Maria Angeles Arredondo-Alcala, Bianca Bustamante, Carolina Gonzalez-Silva, Soledad Matus, Rodrigo Diaz-Espinoza, Antonia Gutierrez, Rodrigo Morales, Claudia Duran-Aniotz, Ines Moreno-Gonzalez

published 15 Jul 2025

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Dissecting cell-free DNA fragmentation variation in tumors using cell line-derived xenograft mouse

Ruiqing Fu, He Amy Su, Yi Zhao, Yafei Tian, Hongyan Chen, Daru Lu

published 15 Jul 2025

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A novel yeast-derived aldehyde-reducing compound MF001 protects against alcohol-induced liver damage

Eun-Ho Lee, Min-Hee Seo, Soo-Young Park, Sulagna Mukherjee, Jae-Ho Lee, Sora Kang, Ji-Yu Lee, Namgyu Lee, Hung Taeck Kwon, Seung-Soon Im

published 10 Jul 2025

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