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Mouse models

Significance of RGS13 expression in lupus B cells

Tomoya Nakajima, Koji Kitagori, Sohei Funakoshi, Mirei Shirakashi, Ryosuke Hiwa, Hideaki Tsuji, Shuji Akizuki, Ran Nakashima, Akio Morinobu, Hajime Yoshifuji

published 08 May 2026

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The ketogenic diet alleviates autoimmune thyroiditis caused by Th17/Treg imbalance by inhibiting the HMGB1/NLRP3 signaling pathway

Yue Luo, Hao Gao, Mengzhen Wang, Zhimin Wang, Zhe Jin, Nan Song, Ziyu Liu, Xiao Yang

published 08 May 2026

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A novel application tunnel in combination with medical training reduces stress induced by frequent intraperitoneal injections and blood draws in mice

Anne Schlutt, Katarina Riesner, Merle Kochan, Ann-Kathrin Meß, Denise Jahn, Isabella Lurje, Wiebke Werner, Felix Heymann, Olivia Kershaw, Frank Tacke, Bernhard Hiebl, Linda Hammerich

published 07 May 2026

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Polyphenol extract of Syzygium brachythyrsum mitigates atherosclerosis in high-fat diet induced ApoE^-/- mice by regulating ROS/Keap1/Nrf2 pathway

He-Ping Liu, Pei-Wen He, Kai-Jing Yu, Qiang Shang, Wen Xu, Xin-Fu Cai

published 05 May 2026

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Trp53 loss drives the neoplastic transformation of Pik3ca^H1047R-induced vascular malformation in a mouse model

Miaolu Tang, Jessica Sallavanti, Matthew Lanza, Danielle Covington, Wei Li

published 04 May 2026

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A digestive cartridge reduces intestinal injury in a murine model of necrotizing enterocolitis

Sarah Z. Wang, Djanira Fernandes, Savas T. Tsikis, Thomas I. Hirsch, Amy Pan, Mikayla Quigley, Valeria Ruiz, Scott C. Fligor, Carter R. Petty, Greta Loring, Stephen Davia, Juhye Kang, Mark Puder

published 30 Apr 2026

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Artemether ameliorates type 1 diabetic liver injury alongside the associated defects in mitochondrial ultrastructure and central carbon metabolism

Qike Fu, Jiaxin Li, Xiufen Gu, Yating Zhang, Pengxun Han, Xuewen Yu, Mumin Shao, Huili Sun, Yuchun Cai

published 29 Apr 2026

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Poldip2 deficiency attenuates lung disease severity in a mouse model of COVID-19

Ruinan Hu, Alejandra Valdivia, Taylor White, Willy Ju, Maegan L. Brockman, Zhan Zhang, Hongyan Qu, Georgette Gafford, Giji Joseph, Samantha Burton, Leda Bassit, Tysheena P. Charles, Raymond F. Schinazi, Rebecca D. Levit, Cynthia A. Derdeyn, Kathy K. Griendling, Bernard Lassègue, Marina S. Hernandes

published 29 Apr 2026

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ATRX function beyond hippocampal CA1 is required for cognitive deficits in mouse models of intellectual disability

Julia T. Brott, Nathalie G. Bérubé

published 28 Apr 2026

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Targeting pancreatic cancer with combined inhibition of EGFR and RAF

Jakob Brandstetter, Lea Goldstein, Tim Schreiber, Rupert Palme, Tobias Lindner, Markus Joksch, Bernd Krause, Brigitte Vollmar, Simone Kumstel

published 24 Apr 2026

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Reappraisal of profibrotic phenotype and cell-cycle state of renal tubular epithelium after ischemia–reperfusion injury

Daichi Fukaya, Wakako Kosakai, Tetsuya Sato, Tsutomu Inoue, Hiroaki Amano, Takeru Kusano, Hirokazu Okada

published 24 Apr 2026

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Targeted transferosomal delivery of cetirizine: A new approach to alopecia management

Noha Talal Zelai

published 24 Apr 2026

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In vivo mouse model of calcific myonecrosis induced by injury

Mai Kuratani, Sho Tsukamoto, Ryo Hamai, Kaori Tsuchiya, Osamu Suzuki, Taketo Yamada, Takenobu Katagiri

published 22 Apr 2026

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