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Mouse models

Mitochondrial oxidative stress promotes the accumulation of advanced glycation end products

Firoz Akhter, Sourav Samanta, Alexandre A. Sosunov, Huawei Wu, Ethan Kim Tieu, Shi Fang Yan, Shirley ShiDu Yan

published 23 Jun 2026

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Omipalisib reduces hyperphosphorylated tau protein by modulating mTOR-autophagy pathway

Haeun Hwang, Namkwon Kim, Subyn Jeon, Yoojin Lee, Jeongmin Son, Seung Ho Jeon, Yeongae Lee, Min Sung Gee, Kyung-Soo Inn, Jong Kil Lee

published 23 Jun 2026

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TNFR2 is expressed by a discrete subset of epidermal T cells with an IL-17 gene signature during psoriasis

Jasmine Ahmed, Carolyn Matthews, Patricia Tulloch, William Lawler, Albert Mendoza, Mikaela Rhoiney, Julie M. Jameson

published 23 Jun 2026

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Tumor-associated M2 macrophages promote prostate cancer invasion through the M-CSF-PCLAF pathway

Yitian Ou, Chunwei Ye, Haiyang Jiang, Yong Zhu, Chengxing Xia, Delin Yang

published 22 Jun 2026

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Optimized detection of caspase-6 activation in a murine inflammation model to inform neurodegenerative disease therapies

Irina Sagarbarria, Jamin Seo, Andrew J. Smith, Elena M. Vazey, Kimberly D. Tremblay, Jesse Mager, Jeanne A. Hardy

published 17 Jun 2026

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Modeling diffuse midline glioma through triple-electrode in utero electroporation of the developing mouse pons

Madisen S. Mason, Hosbaldo Morales Murillo, Madisyn G. Dudek, Samantha E. Maher, Santos J. Franco

published 17 Jun 2026

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Production of anti-inflammatory and antidiabetic oligosaccharides from okra mucilage through one-step microbial fermentation

Ayaz Ahmad, Imdad Ullah Khan, Yusra Jamil, Aymen Ajmal, Murad Ali, Muhammad Ihtesham, Douglas Law, Patricio R. De los Ríos-Escalante, Saeedah Almutairi, Wahidah H. Al-Qahtani, Ahmed Othman Alsabih, Mostafa A. Abdel-Maksoud, Waheed Ahmad

published 11 Jun 2026

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Gene therapy rescues cone function in an all-cone retina mouse model with the most common cone opsin C203R missense mutation

Marion E. Cahill, Kathryn Chmelik, Brooke A. Brothers, Madyson E. Ashcraft, Tongju Guan, Artjola Puja, Yinxiao Xiang, Lee M. Shaw, Jianhai Du, Wen-Tao Deng

published 11 Jun 2026

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Replicative and stress-induced premature senescence distinctively affect the endothelial anticoagulation capacity

Akiko Katayama, Koji Ikeda, Tomoya Kitani, Ekura Yamazaki, Daisuke Ueno, Fumiaki Ito, Satoaki Matoba

published 09 Jun 2026

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EP300 promotes bladder cancer cell migration through SNAI2

Qing Zhang, Chongjie He, Yingzhou Hong, Tao Huang, Shuangsheng Deng, Cheng Peng, Haifeng Wang, Chunming Guo

published 08 Jun 2026

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Neutrophil extracellular traps in the animal model of adenine-induced chronic kidney disease

Alexandra Gaál Kovalčíková, Gabriela Forraiová, Nelia Korotushak, Veronika Borbélyová, Diana Vavrincová-Yaghi, Peter Vavrinec, Ľudmila Podracká, Peter Celec

published 05 Jun 2026

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Establishment of a mouse intrauterine adhesion model via transvaginal mechanical injury guided by abdominal ultrasound

Xuan Liu, Panpan Yuan, Xindi Zhang, Xin Liu, Caixiang Li, Hui Zhao, Yinci Zhang, Fan Li, Ping Zhou

published 05 Jun 2026

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The role and targeting potential analysis of angiogenesis-related target THY1 in DSS-induced acute colitis in mice

Pengliang Zhang, Xianmin Liu, Shuang Chen, Yingjian Zhang

published 02 Jun 2026

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