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Mouse models

Dysregulated lactate metabolism synergizes with ALS genetic risk factors to accelerate motor decline

Shweta Tendulkar, Tong Wu, [ ... ], Aaron DiAntonio

MMP-2 associated imbalance of VEGF/Endostatin is linked to suppression of the PI3K/AKT/HIF-1α pathway in steroid-induced osteonecrosis of femoral head

Guangyang Zhang, Zhaopu Jing, [ ... ], Qichun Song

PDGFRα-positive mesenchymal stem/stromal cells contribute to autonomous vascular formation through in-body tissue architecture

Satoru Morikawa, Masaki Yoda, [ ... ], Yasuhide Nakayama

Impaired dynein function preserves spinal interneuron survival and positioning in an ALS-like mouse model

Eleni Christoforidou, Jordan S. Rowe, [ ... ], Majid Hafezparast

Primary cilia in osteoblasts and osteocytes are required for skeletal development and mechano-adaptation

Mariana Moraes de Lima Perini, Alyssa F. Fayemi, [ ... ], Jiliang Li

A phosphorous-based dendrimer targets mitochondria and normalizes the keratinocyte proliferation/differentiation balance to improve psoriasis

Emily Clement, Ranime Jebbawi, [ ... ], Rémy Poupot

A novel genetic strategy to interrogate an unknown phenotypic modifier: Sdhc KO-Robertsonian mice develop frequent thyroid abnormalities with papillary thyroid carcinoma-like features

Jean-Pierre Bayley, Heggert G. Rebel, Peter Devilee

5-HT1B receptor agonists promote Schwann cell myelination

Yuka Kobayashi-Ujiie, Keiko Hiraki-Kamon, Shuji Wakatsuki, Toshiyuki Araki

STING pathway contributes to Steroid-Hyporesponsive Lung Inflammation in DSS-induced colitis mice model

Mariam Wed Eladham, Narjes Saheb Sharif-Askari, [ ... ], Rabih Halwani

APOE4 and doxorubicin impair inhibitory interneuron function and homeostatic regulation in the entorhinal cortex

Nancy Luo, Harshul Pandit, [ ... ], G. William Rebeck

Inhibition of transient receptor potential vanilloid 1 (TRPV1) by a novel selective antagonist for anti-nociceptive effect on inflammatory pain without hyperthermia

Jialiang Guan, Chenru Zhao, Qiqi Zhou, Chao Zhu

M₅ positive allosteric modulation alleviates parkinsonian motor deficits

Nicole E. Chambers, Dominic Hall, [ ... ], Mark S. Moehle

Impact of blast exposure on visual pathway: Mechanism exploration and novel diagnostic perspectives

Yue Wang, Nan Yang, [ ... ], Rongdi Yuan

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