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Molecular development

Cyclosporine A eyedrops with self-nanoemulsifying drug delivery systems have improved physicochemical properties and efficacy against dry eye disease in a murine dry eye model

Seung Pil Bang, Chang Yeor Yeon, Nirpesh Adhikari, Sanjiv Neupane, Harim Kim, Dong Cheol Lee, Myeong Jin Son, Hyun Gyo Lee, Jae-Young Kim, Jong Hwa Jun

published 18 Nov 2019

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Mechanisms of African swine fever virus pathogenesis and immune evasion inferred from gene expression changes in infected swine macrophages

James J. Zhu, Palaniappan Ramanathan, Elizabeth A. Bishop, Vivian O’Donnell, Douglas P. Gladue, Manuel V. Borca

published 14 Nov 2019

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Effects of tetracycline on myocardial infarct size in obese rats with chemically-induced colitis

Yury Yu Borshchev, Sarkis M. Minasian, Inessa Yu Burovenko, Victor Yu Borshchev, Egor S. Protsak, Natalia Yu Semenova, Olga V. Borshcheva, Michael M. Galagudza

published 12 Nov 2019

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Autophagy deficiency exacerbates colitis through excessive oxidative stress and MAPK signaling pathway activation

Minori Kubota, Kazuki Kakimoto, Takatoshi Nakagawa, Eiko Koubayashi, Kei Nakazawa, Hideki Tawa, Yuki Hirata, Toshihiko Okada, Ken Kawakami, Akira Asai, Shuhei Hosomi, Toshihisa Takeuchi, Shinya Fukunishi, Takuya Inoue, Michio Asahi, Kazuhide Higuchi

published 08 Nov 2019

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Association of serum leptin and adiponectin concentrations with echocardiographic parameters and pathophysiological states in patients with cardiovascular disease receiving cardiovascular surgery

Tatsuya Sawaguchi, Toshiaki Nakajima, Akiko Haruyama, Takaaki Hasegawa, Ikuko Shibasaki, Takafumi Nakajima, Hiroyuki Kaneda, Takuo Arikawa, Syotaro Obi, Masashi Sakuma, Hironaga Ogawa, Yuusuke Takei, Shigeru Toyoda, Fumitaka Nakamura, Shichiro Abe, Hirotsugu Fukuda, Teruo Inoue

published 08 Nov 2019

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UM171 induces a homeostatic inflammatory-detoxification response supporting human HSC self-renewal

Jalila Chagraoui, Bernhard Lehnertz, Simon Girard, Jean Francois Spinella, Iman Fares, Elisa Tomellini, Nadine Mayotte, Sophie Corneau, Tara MacRae, Laura Simon, Guy Sauvageau

published 08 Nov 2019

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Synergistic immuno-modulatory activity in human macrophages of a medicinal mushroom formulation consisting of Reishi, Shiitake and Maitake

Brody Mallard, David N. Leach, Hans Wohlmuth, Joe Tiralongo

published 07 Nov 2019

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Tissue-type plasminogen activator selectively inhibits multiple toll-like receptors in CSF-1-differentiated macrophages

Lipsa Das, Pardis Azmoon, Michael A. Banki, Elisabetta Mantuano, Steven L. Gonias

published 07 Nov 2019

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Elevated interleukin-25 and its association to Th2 cytokines in systemic lupus erythematosus with lupus nephritis

Malarvili Selvaraja, Maha Abdullah, Masita Arip, Voon Kin Chin, Anim Shah, Syafinaz Amin Nordin

published 07 Nov 2019

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Bacillus Calmette-Guérin (BCG) therapy lowers the incidence of Alzheimer’s disease in bladder cancer patients

Ofer N. Gofrit, Benjamin Y. Klein, Irun R. Cohen, Tamir Ben-Hur, Charles L. Greenblatt, Hervé Bercovier

published 07 Nov 2019

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Understanding allergic multimorbidity within the non-eosinophilic interactome

Daniel Aguilar, Nathanael Lemonnier, Gerard H. Koppelman, Erik Melén, Baldo Oliva, Mariona Pinart, Stefano Guerra, Jean Bousquet, Josep M. Anto

published 06 Nov 2019

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Efficacy of interleukin 10 gene hydrofection in pig liver vascular isolated ‘in vivo’ by surgical procedure with interest in liver transplantation

Luis Sendra, María José Herrero, Eva María Montalvá, Inmaculada Noguera, Francisco Orbis, Ana Díaz, Rafael Fernández-Delgado, Rafael López-Andújar, Salvador F. Aliño

published 05 Nov 2019

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Average and time-specific maternal prenatal inflammatory biomarkers and the risk of labor epidural associated fever

Dominique Y. Arce, Andrea Bellavia, David E. Cantonwine, Olivia J. Napoli, John D. Meeker, Tamarra James-Todd, Thomas F. McElrath, Lawrence C. Tsen

published 05 Nov 2019

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