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Molecular development

Targeting the Exon2 splice cis-element in PD-1 and its effects on lymphocyte function

Yuto Tan, Naoko Kumagai-Takei, Yurika Shimizu, Akira Yamasaki, Mari Hara-Yamamoto, Shigeru Mitani, Tatsuo Ito

published 08 Sep 2025

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Modulation of cellular adhesion, contractility, and migration by MiuA: A comprehensive analysis of its biomechanical impact

Carsten Alexander Baltes, Friederike Nolle, Kathi Michèle Kaiser, Erbara Gjana, Kristin Sander, Karin Jacobs, Rhoda Joy Hawkins, Franziska Lautenschläger

published 05 Sep 2025

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Activation and proliferation profiles of M.tuberculosis specific dual functional CD4+T cells from smear negative pulmonary TB patients

Ahmed Esmael, Adane Mihret, Tamrat Abebe, Daniel Mussa, Sebsib Neway, Joel Ernst, Jyothi Rengarajan, Liya Wassie, Rawleigh Howe

published 03 Sep 2025

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Effect of repeated intratracheal instillation of incense smoke condensate in mice

In-Hyeon Kim, Je-Hein Kim, Se-Woong Park, Han Na Suh, Su-Jin Lim, Min-Sung Kang, Hyeon-Young Kim, Dong Im Kim, Moonjung Hyun, Sung-Hwan Kim

published 02 Sep 2025

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Phytochemical and pharmacoinformatics analysis of a traditional antipsoriatic oil formulation for its potential against proinflammatory cytokines TNF-α and IL-17A

Nayak Deeksha Dayanand, Vasudha Devi, Shama Prasada Kabbekodu, Arul Amuthan, Sathish Pai B, Rajasekhar Chinta

published 02 Sep 2025

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Interaction of coexposure to inorganic arsenic and manganese: Tight junction injury of the blood–brain barrier and the relationship between oxidative stress and inflammatory cytokines in glial cells

Toshiaki Hitomi, Hiroko Okuda, Ayako Takata, Hiroshi Yamauchi

published 25 Aug 2025

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Downhill running regulates cardiac immune response through GCN2

Xinyue Bai, Wanting Zhang, Yingyue Zhang, Xin Xu

published 22 Aug 2025

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A reduction in serum IFN-γ, IL-1β, IL-6, and GM-CSF serves as potential markers for a positive outcome to lumbar epidural steroid injections

Pornpan Chalermkitpanit, Weerasak Singhatanadgige, Wicharn Yingsakmongkol, Teerachat Tanasansomboon, Manassanan Jitjumnong, Sittisak Honsawek

published 22 Aug 2025

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Agent-based modeling of macrophage-fibroblast interactions in the immune response to biomaterials

Jennifer Riccio, Luca Presotto, Shir Bahiri, Liad Doniza, Donato Inverso, Laura Sironi, Uri Nevo, Giuseppe Chirico

published 19 Aug 2025

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Immune cells play a critical role in cytokine- and endotoxin-mediated endothelial permeability

Patricia Gogesch, Samira Ortega Iannazzo, Nicole Rupp, Joachim Rom, Markus Kreuz, Kristin Reiche, Martina Anzaghe, Zoe Waibler, on behalf of the imSAVAR Consortium

published 14 Aug 2025

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Cytokines interferon−γ− inducible protein 10 and granulocyte−macrophage colony−stimulating factor are associated with psychiatric symptoms in opioid−dependent patients: A cross− sectional study

Kristin Nygård−Odeh, Hedda Soløy−Nilsen, Magnhild Gangsøy−Kristiansen, Ole Lars Brekke, Tom Eirik Mollnes, Michael Berk

published 07 Aug 2025

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LBH589 reduces oxidized mitochondrial DNA and suppresses NLRP3 inflammasome activation to relieve pulmonary inflammation

Changwen Ning, Fenghua Gao, Zhe Wang, Huaying An, Pengyu Liu, Yanan Sun, Ru Li, Zhuyang Song, Yuanyuan Yuan, Jinlong Li, Jun Ma, Xingwei Jiang, Qun Yu

published 04 Aug 2025

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Trypanosoma vivax elicits both Th1 and Th2 immunological responses in experimentally infected cattle

Cristina Cholota-Iza, Marbel Torres-Arias, María Augusta Chávez-Larrea, Fausto Bedoya-Paez, Mishell Cisneros-Ruiz, Georgina Morales-Moreno, Jorge Ron-Román, Claude Saegerman, Armando Reyna-Bello

published 31 Jul 2025

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