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Molecular development

Towards a Rigorous Assessment of Systems Biology Models: The DREAM3 Challenges

Robert J. Prill, Daniel Marbach, Julio Saez-Rodriguez, Peter K. Sorger, Leonidas G. Alexopoulos, Xiaowei Xue, Neil D. Clarke, Gregoire Altan-Bonnet, Gustavo Stolovitzky

published 23 Feb 2010

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FcγRIIb Inhibits Allergic Lung Inflammation in a Murine Model of Allergic Asthma

Nilesh Dharajiya, Swapnil V. Vaidya, Hiroki Murai, Victor Cardenas, Alexander Kurosky, Istvan Boldogh, Sanjiv A. Sur

published 22 Feb 2010

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Fibroblasts Express Immune Relevant Genes and Are Important Sentinel Cells during Tissue Damage in Rainbow Trout (Oncorhynchus mykiss)

Hans-Christian Ingerslev, Carlo Gunnar Ossum, Thomas Lindenstrøm, Michael Engelbrecht Nielsen

published 18 Feb 2010

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CD8⁺ DC, but Not CD8⁻DC, Isolated from BCG-Infected Mice Reduces Pathological Reactions Induced by Mycobacterial Challenge Infection

Xiaoling Gao, Shuhe Wang, Yijun Fan, Hong Bai, Jie Yang, Xi Yang

published 18 Feb 2010

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Atopic Dermatitis-Like Disease and Associated Lethal Myeloproliferative Disorder Arise from Loss of Notch Signaling in the Murine Skin

Alexis Dumortier, André-Dante Durham, Matteo Di Piazza, Sophie Vauclair, Ute Koch, Gisèle Ferrand, Isabel Ferrero, Shadmehr Demehri, Lynda Li Song, Andrew G. Farr, Warren J. Leonard, Raphael Kopan, Lucio Miele, Daniel Hohl, Daniela Finke, Freddy Radtke

published 18 Feb 2010

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Agent-Based Modeling of Endotoxin-Induced Acute Inflammatory Response in Human Blood Leukocytes

Xu Dong, Panagiota T. Foteinou, Steven E. Calvano, Stephen F. Lowry, Ioannis P. Androulakis

published 18 Feb 2010

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The Virion Host Shut-Off (vhs) Protein Blocks a TLR-Independent Pathway of Herpes Simplex Virus Type 1 Recognition in Human and Mouse Dendritic Cells

Christopher R. Cotter, Marie L. Nguyen, Jacob S. Yount, Carolina B. López, John A. Blaho, Thomas M. Moran

published 18 Feb 2010

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Atlas of Signaling for Interpretation of Microarray Experiments

Ekaterina Kotelnikova, Natalia Ivanikova, Andrey Kalinin, Anton Yuryev, Nikolai Daraselia

published 17 Feb 2010

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Increased Sensitivity of CD4+ T-Effector Cells to CD4+CD25+ Treg Suppression Compensates for Reduced Treg Number in Asymptomatic HIV-1 Infection

Georgina Thorborn, Laura Pomeroy, Heidi Isohanni, Melissa Perry, Barry Peters, Annapurna Vyakarnam

published 17 Feb 2010

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Mouse Bone Marrow-Derived Mesenchymal Stromal Cells Turn Activated Macrophages into a Regulatory-Like Profile

Julian Maggini, Gerardo Mirkin, Ianina Bognanni, Josefina Holmberg, Isabel M. Piazzón, Irene Nepomnaschy, Héctor Costa, Cristian Cañones, Silvina Raiden, Mónica Vermeulen, Jorge R. Geffner

published 16 Feb 2010

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Soluble Erythropoietin Receptor Contributes to Erythropoietin Resistance in End-Stage Renal Disease

Eliyahu V. Khankin, Walter P. Mutter, Hector Tamez, Hai-Tao Yuan, S. Ananth Karumanchi, Ravi Thadhani

published 16 Feb 2010

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Prolonged Graft Survival in Older Recipient Mice Is Determined by Impaired Effector T-Cell but Intact Regulatory T-Cell Responses

Christian Denecke, Damanpreet Singh Bedi, Xupeng Ge, Irene Kyung-eun Kim, Anke Jurisch, Anne Weiland, Antje Habicht, Xian C. Li, Stefan G. Tullius

published 16 Feb 2010

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High Log-Scale Expansion of Functional Human Natural Killer Cells from Umbilical Cord Blood CD34-Positive Cells for Adoptive Cancer Immunotherapy

Jan Spanholtz, Marleen Tordoir, Diana Eissens, Frank Preijers, Arnold van der Meer, Irma Joosten, Nicolaas Schaap, Theo M. de Witte, Harry Dolstra

published 15 Feb 2010

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