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Molecular development

mTORC1-S6K Activation by Endotoxin Contributes to Cytokine Up-Regulation and Early Lethality in Animals

Po-Shun Lee, Anna S. K. Wilhelmson, Anton P. Hubner, Samuel B. Reynolds, Dana A. Gallacchi, Terry T. Chiou, David J. Kwiatkowski

published 21 Dec 2010

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Characterization of Protective Human CD4⁺CD25⁺ FOXP3⁺ Regulatory T Cells Generated with IL-2, TGF-β and Retinoic Acid

Ling Lu, Xiaohui Zhou, Julie Wang, Song Guo Zheng, David A. Horwitz

published 17 Dec 2010

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α-Galactosylceramide Analogs with Weak Agonist Activity for Human iNKT Cells Define New Candidate Anti-Inflammatory Agents

Gabriel Bricard, Manjunatha M. Venkataswamy, Karl O. A. Yu, Jin S. Im, Rachel M. Ndonye, Amy R. Howell, Natacha Veerapen, Petr A. Illarionov, Gurdyal S. Besra, Qian Li, Young-Tae Chang, Steven A. Porcelli

published 17 Dec 2010

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Enumeration of Functional T-Cell Subsets by Fluorescence-Immunospot Defines Signatures of Pathogen Burden in Tuberculosis

Rosalyn Casey, Deena Blumenkrantz, Kerry Millington, Damien Montamat-Sicotte, Onn Min Kon, Melissa Wickremasinghe, Samuel Bremang, Murphy Magtoto, Saranya Sridhar, David Connell, Ajit Lalvani

published 14 Dec 2010

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Coxiella burnetii, the Agent of Q Fever, Replicates within Trophoblasts and Induces a Unique Transcriptional Response

Amira Ben Amara, Eric Ghigo, Yannick Le Priol, Catherine Lépolard, Suzana P. Salcedo, Emmanuel Lemichez, Florence Bretelle, Christian Capo, Jean-Louis Mege

published 14 Dec 2010

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Hijacking of the Pleiotropic Cytokine Interferon-γ by the Type III Secretion System of Yersinia pestis

Claire Gendrin, Stéphane Sarrazin, David Bonnaffé, Jean-Michel Jault, Hugues Lortat-Jacob, Andréa Dessen

published 13 Dec 2010

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Safety and T Cell Modulating Effects of High Dose Vitamin D₃ Supplementation in Multiple Sclerosis

Joost Smolders, Evelyn Peelen, Mariëlle Thewissen, Jan Willem Cohen Tervaert, Paul Menheere, Raymond Hupperts, Jan Damoiseaux

published 13 Dec 2010

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Effects of Inhibition of Interleukin-6 Signalling on Insulin Sensitivity and Lipoprotein (A) Levels in Human Subjects with Rheumatoid Diseases

Olaf Schultz, Frank Oberhauser, Jasemine Saech, Andrea Rubbert-Roth, Moritz Hahn, Wilhelm Krone, Matthias Laudes

published 13 Dec 2010

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Cytokine Profiles in Asthma Families Depend on Age and Phenotype

Katrin Pukelsheim, Tobias Stoeger, David Kutschke, Koustav Ganguly, Matthias Wjst

published 13 Dec 2010

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Comparative Analysis of the Lambda-Interferons IL-28A and IL-29 regarding Their Transcriptome and Their Antiviral Properties against Hepatitis C Virus

Julia Diegelmann, Florian Beigel, Kathrin Zitzmann, Artur Kaul, Burkhard Göke, Christoph J. Auernhammer, Ralf Bartenschlager, Helmut M. Diepolder, Stephan Brand

published 08 Dec 2010

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Alanine Aminotransferase Decreases with Age: The Rancho Bernardo Study

Mamie H. Dong, Ricki Bettencourt, Elizabeth Barrett-Connor, Rohit Loomba

published 08 Dec 2010

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A Host Defense Mechanism Involving CFTR-Mediated Bicarbonate Secretion in Bacterial Prostatitis

Chen Xie, Xiaoxiao Tang, Wenming Xu, Ruiying Diao, Zhiming Cai, Hsiao Chang Chan

published 07 Dec 2010

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The Type of Responder T-Cell Has a Significant Impact in a Human In Vitro Suppression Assay

Srikanta Jana, Hope Campbell, Jeffrey Woodliff, Jill Waukau, Parthav Jailwala, Jugal Ghorai, Soumitra Ghosh, Sanja Glisic

published 03 Dec 2010

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