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Molecular development

IFN-β therapy rescues dysregulated IFN-stimulated proteins, serum cytokines, and neurotrophic factors in multiple sclerosis: Multiplex analysis of short-term and long-term IFN responses

Lei Li, Maya Olcer, Zhe Wang, Yaerin Song, Jeffrey Ke, Xuan Feng, Anthony T. Reder

published 19 Sep 2025

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Gene profiles of peripheral white blood cells as potential predictors of pregnancy in embryo-recipient heifers

Mariam Raliou, Marie Margarete Meyerholz-Wohllebe, Doulaye Dembélé, Kirsten Mense, Maike Heppelmann, Christophe Richard, Pascale Chavatte-Palmer, Isabelle Dieuzy-Labaye, David Smith, Peter Zieger, Hans-Joachim Schuberth, Marion Schmicke, Iain Martin Sheldon, Olivier Sandra

published 15 Sep 2025

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Study on the effect of modified Liu-an decoction on Th1/Th2 function in Guinea pigs with cough variant asthma through the Notch signal pathway

Fangwei Xu, Jian Deng, Ningning Zhang, Kimberly XinTing Leow, Panpan Li, Chen Lu, Yuhang Chen, Ye Zhang, Liqun Wu

published 15 Sep 2025

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Analytical approach of synchronous and asynchronous update schemes applied to solving biological Boolean networks

Antonio Bensussen, J. Arturo Arciniega-González, Elena R. Álvarez-Buylla, Juan Carlos Martínez-García

published 12 Sep 2025

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Induction of an early IFN-γ cellular response and high plasma levels of SDF-1α are inversely associated with COVID-19 severity and residence in rural areas in Kenyan patients

Perpetual Wanjiku, Benedict Orindi, John Kimotho, Shahin Sayed, Reena Shah, Mansoor Saleh, Jedidah Mwacharo, Christopher Maronga, Viviane Olouch, Ann Karanu, Jasmit Shah, Zaitun Nneka, Lynette Isabella Ochola-Oyier, Abdirahman I. Abdi, Susanna Dunachie, Philip Bejon, Eunice W. Nduati, Francis M. Ndungu

published 11 Sep 2025

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Identification of potential inflammation markers for outgrowth of cow’s milk allergy

Diana M. Hendrickx, Mengyichen Long, PRESTO study team , Harm Wopereis, Renate G. van der Molen, Clara Belzer

published 10 Sep 2025

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Interferon-gamma 1b-induced gene expression alters neutrophil function in patients with chronic granulomatous disease

Daniel R. Ambruso, Natalie J. Briones, Alexander D. Tran, Bridget Sanford, Christine Childs, Ben Z. Katz, Michael Ellison, Richard B. Johnston, Kenneth L. Jones

published 08 Sep 2025

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Targeting the Exon2 splice cis-element in PD-1 and its effects on lymphocyte function

Yuto Tan, Naoko Kumagai-Takei, Yurika Shimizu, Akira Yamasaki, Mari Hara-Yamamoto, Shigeru Mitani, Tatsuo Ito

published 08 Sep 2025

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Modulation of cellular adhesion, contractility, and migration by MiuA: A comprehensive analysis of its biomechanical impact

Carsten Alexander Baltes, Friederike Nolle, Kathi Michèle Kaiser, Erbara Gjana, Kristin Sander, Karin Jacobs, Rhoda Joy Hawkins, Franziska Lautenschläger

published 05 Sep 2025

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Activation and proliferation profiles of M.tuberculosis specific dual functional CD4+T cells from smear negative pulmonary TB patients

Ahmed Esmael, Adane Mihret, Tamrat Abebe, Daniel Mussa, Sebsib Neway, Joel Ernst, Jyothi Rengarajan, Liya Wassie, Rawleigh Howe

published 03 Sep 2025

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Effect of repeated intratracheal instillation of incense smoke condensate in mice

In-Hyeon Kim, Je-Hein Kim, Se-Woong Park, Han Na Suh, Su-Jin Lim, Min-Sung Kang, Hyeon-Young Kim, Dong Im Kim, Moonjung Hyun, Sung-Hwan Kim

published 02 Sep 2025

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Phytochemical and pharmacoinformatics analysis of a traditional antipsoriatic oil formulation for its potential against proinflammatory cytokines TNF-α and IL-17A

Nayak Deeksha Dayanand, Vasudha Devi, Shama Prasada Kabbekodu, Arul Amuthan, Sathish Pai B, Rajasekhar Chinta

published 02 Sep 2025

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Interaction of coexposure to inorganic arsenic and manganese: Tight junction injury of the blood–brain barrier and the relationship between oxidative stress and inflammatory cytokines in glial cells

Toshiaki Hitomi, Hiroko Okuda, Ayako Takata, Hiroshi Yamauchi

published 25 Aug 2025

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